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Cafedrine

Product Name
Cafedrine
CAS No.
58166-83-9
Chemical Name
Cafedrine
Synonyms
Cafedrine;Cafedrina;Brn 0583473;l-Cafedrine;(-)-Cafedrine;Cafedrina [inn-spanish];7-(2-(2-Hydroxy-1-methylphenethylamino)ethyl)theophylline;7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline;7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione;3,7-Dihydro-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione
CBNumber
CB01178203
Molecular Formula
C18H23N5O3
Formula Weight
357.412
MOL File
58166-83-9.mol
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Cafedrine Property

Boiling point:
591.6±52.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
pka
13.90±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C799035
Product name
(-)-Cafedrine
Packaging
5mg
Price
$50
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010919
Product name
CAFEDRINE
Purity
95.00%
Packaging
5MG
Price
$497.41
Updated
2021/12/16
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Cafedrine Chemical Properties,Usage,Production

Originator

Praxinor,Merck Lipha Sante

Uses

(-)-Cafedrine is composed of linked Phenylpropanolamine (P336100) and Theophylline (T343850). It is used to regulate and restore blood pressure.

Manufacturing Process

7.5 g 7-(2-bromethyl)theophylline, 11.3 g 1-norphedrine and 12.5 ml isopropanol were refluxed with stirring for 6 hours. Then 30 ml ethanol and HCl in ethanol to pH 5-6 were added. The mixture stood for 2 days. 9.6 g of 7-(2-(beta-hydroxy-alpha-methylphenethylamino)ethyl)theophylline hydrochloride was filtered off and dried. MP 243°-244°C.
In practice it is usually used as free base.

Therapeutic Function

Analeptic

Cafedrine Preparation Products And Raw materials

Raw materials

Preparation Products

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Cafedrine Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19704
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58

58166-83-9, CafedrineRelated Search:


  • Cafedrine
  • 3,7-Dihydro-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione
  • 7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
  • 7-(2-((Alphas,betar)-beta-hydroxy-alpha-methylphenethylamino)ethyl)-1,3-dimethyl-2,6(1H,3H)purindion
  • 7-(2-(2-Hydroxy-1-methylphenethylamino)ethyl)theophylline
  • 7-(2-{[(1R,2S)-1-Hydroxy-1-phenyl-2-propanyl]amino}ethyl)-1,3-dim ethyl-3,7-dihydro-1H-purine-2,6-dione
  • 7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline
  • Brn 0583473
  • Cafedrina
  • Cafedrina [inn-spanish]
  • 1H-Purine-2,6-dione, 3,7-dihydro-7-[2-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino]ethyl]-1,3-dimethyl-
  • (-)-Cafedrine
  • l-Cafedrine
  • 58166-83-9