(-)-ANABASINE

ChemicalBook > CAS DataBase List > (-)-ANABASINE

Product Name: (-)-ANABASINE
CAS No.: 494-52-0
Chemical Name: (-)-ANABASINE
Synonyms: Anabasin;Anabazin;ANOBASINE;ANABASINE;Neonikoti;Neonikotin;NEONICOTINE;L-ANABASINE;(-)-anabasin;(-)-ANABASINE
CBNumber: CB0119964
Molecular Formula: C10H14N2
Formula Weight: 162.23
MOL File: 494-52-0.mol

Less

(-)-ANABASINE Property

Melting point:: 9°C
Boiling point:: 270-272°C
alpha: D20 -83.1°
Density: 1,0455 g/cm³
refractive index: 1.5430
Flash point:: 93°C
storage temp.: 2-8°C
solubility: DMSO : 100 mg/mL (616.41 mM)
pka: 8.98±0.10(Predicted)
form: Liquid
Merck: 14,619
BRN: 82637
CAS DataBase Reference: 494-52-0(CAS DataBase Reference)
NIST Chemistry Reference: Pyridine, 3-(2-piperidinyl)-, (S)-(494-52-0)
EPA Substance Registry System: Anabasine (494-52-0)

Less

Safety

Hazard Codes: T
Risk Statements: 27/28-51/53-23/24/25
Safety Statements: 28-36/37-45-61-36/37/39-28A
RIDADR: 3140
RTECS: BV4375000
HazardClass: 6.1
PackingGroup: I
HS Code: 29333990
Hazardous Substances Data: 494-52-0(Hazardous Substances Data)
Toxicity: LDLo orl-dog: 50 mg/kg JPETAB 48,95,33

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

TRC

Product number: A637170
Product name: (S)-Anabasine,>98%ee
Packaging: 100mg
Price: $350
Updated: 2021/12/16

TRC

Product number: A637170
Product name: (S)-Anabasine,>98%ee
Packaging: 500mg
Price: $1455
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HBL0000006
Product name: (-)-ANABASINE
Purity: 95.00%
Packaging: 1G
Price: $1593.9
Updated: 2021/12/16

Activate Scientific

Product number: AS7078-A
Product name: (S)-3-(Piperidin-2-yl)pyridine
Purity: 95+% ee
Packaging: 5G
Price: $2356
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA17898
Product name: (S)-Anabasine
Packaging: 500mg
Price: $675
Updated: 2021/12/16

Less

(-)-ANABASINE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Oil

Uses

Anabasine occurs in the tobacco speciesNicotiana glauca, Anabasis aphylla L.,Chenopodiaceae, and Solanaceae. It is usedas an insecticide and as a metal anticorrosiveagent.

Uses

(S)-ANABASINE is used as a kind of Nicotinic receptor agonist.

Definition

ChEBI: The (S)-enantiomer of anabasine.

Health Hazard

The acute toxic symptoms include increasedsalivation, confusion, disturbed vision, photophobia,nausea, vomiting, diarrhea, respiratorydistress, and convulsions. It causesrespiratory muscle stimulation similar to thatcaused by lobeline. An oral lethal dose indogs is 50 mg/kg. A subcutaneous lethaldose in guinea pigs is 10 mg/kg.

Biological Activity

Anabasine ((S)-Anabasine) is an alkaloid, a component of tobacco. Anabasine is a botanical insecticide that acts as a pan-agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization in TE671 cells endogenously expressing human myogenic nAChRs (EC50=0.7 μM).

Safety Profile

Poison by ingestion,subcutaneous, and intravenous routes. Moderately toxicby skin contact. An experimental teratogen. Insecticide.Acute and subacute toxicity: increased salivation, vertigo,confusion, disturbed vision and hearing, photophobia,cold ext

in vivo

Anabasine significantly reverses the impairment at the 0.2 mg/kg (p<0.05) and 2 mg/kg doses (p<0.025). Anabasine does not have any significant effects on response latency when administered alone. The 0.06 mg/kg Anabasine dose, in fact, significantly (p<0.05) exacerbates the dizocilpine-induced impairment. None of these Anabasine doses affects choice accuracy on their own. Individual dose comparisons show that the 0.06 mg/kg Anabasine dose plus dizocilpine (6.7±2.6) causes a significant (p<0.05) increase in non-response trials compare with dizocilpine alone (2.1±0.8).

(-)-ANABASINE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

(-)-ANABASINE Suppliers

Belgium 1 Canada 1 China 89 Europe 1 Germany 3 India 4 Japan 1 Russia 1 Ukraine 2 United Kingdom 5 United States 21 Global 129

Jiangsu yize medical technology co. LTD

Tel: 18550739526
Email: 3394205705@qq.com
Country: China
ProdList: 9411
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11714
Advantage: 57

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-83725681-603
Fax: +86 755 28094224
Country: China
ProdList: 4505
Advantage: 50

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6139
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22519
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25015
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9552
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3924
Advantage: 50

Shanghai Meishui Chemical Technology Co., Ltd

Tel: 021-60549325 18616193163
Fax: 021-33250306
Country: China
ProdList: 4528
Advantage: 56

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9986
Advantage: 55

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15185
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5877
Advantage: 58

LABTER PHARMATECH(BEIJING) CO.,LTD

Tel: 010-56330744 18310155299
Fax: 010-56330744
Email: sales@labter.com.cn
Country: China
ProdList: 23339
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9947
Advantage: 58

Chengdu Dianchun Technology Co., Ltd

Tel: 400-1166-196 18502815961
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14623
Advantage: 60

Guangzhou Jhd Chemical Reagent Co., Ltd.

Tel: 020-84383047
Fax: 020-84380294
Email: sales@jhd.com.cn
Country: China
ProdList: 9190
Advantage: 65

Wuxi AppTec

Tel: 022-59987777 13552403979
Email: jia_guoqiang@wuxiapptec.com
Country: China
ProdList: 22346
Advantage: 58

Mirro Chemical Co.,Ltd.

Tel: 0086-15313090952
Fax: 0086-010-80236392
Country: China
ProdList: 2355
Advantage: 58

Aikon International Limited

Tel: 025-66113011 18112977050
Fax: (5)02557626880
Email: cb6@aikonchem.com
Country: China
ProdList: 15495
Advantage: 58

Bejing Famous Pharmaceutical Technology Co., Ltd.

Tel: 13331045123
Fax: 86-10-80339217
Email: 1963319514@qq.com
Country: China
ProdList: 14234
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 24971
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 400-400-400-9004166 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52712
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55827
Advantage: 58

Henan Alfa Chemical Co., Ltd

Tel: +8618339805032
Email: alfa4@alfachem.cn
Country: China
ProdList: 12755
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19994
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12382
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28180
Advantage: 58

Henan Pumei Jihua Pharmaceutical Technology Co., Ltd.

Tel: 037188900765 18037465274
Fax: QQ3430974218
Email: enyawanglei@sina.cn
Country: China
ProdList: 13576
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49390
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49323
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 15093356674;
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29826
Advantage: 58

ShangHai Anpel Co, Ltd.

Tel: 18501792038; 18501792038
Email: shanpel@anpel.com.cn
Country: China
ProdList: 9614
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: 029-61856359 18690052321
Fax: 029-88380327
Email: 1027@dideu.com
Country: China
ProdList: 10010
Advantage: 58

Wuxi Helen Biotechnology Co., Ltd.,

Tel: 0510-85629785 18013409632
Fax: 0510-85625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 14092
Advantage: 58

Shanghai Hewu Biotechnology Co., LTD

Tel: 021-57886085 17317861055
Email: shhebio@126.com
Country: CHINA
ProdList: 7975
Advantage: 58

Henan Weitesi Chemical Technology Co. LTD

Tel: 0371-0371-55135753 18003832934
Fax: QQ：2853979818
Email: 2853979818@qq.com
Country: China
ProdList: 10002
Advantage: 58

NORANA GROUP

Tel: 027-027-59209883 17386169806
Fax: 027-59209883
Email: service@nornachem.com
Country: China
ProdList: 4604
Advantage: 58

cjbscvictory

Tel: 13348960310 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 9946
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44490
Advantage: 58

Hubei Xinkang Pharmaceutical Chemical Co., Ltd

Tel: 027-027-59308705 18871579363
Fax: 027-59308705
Email: 1248680011@qq.com
Country: China
ProdList: 9984
Advantage: 58

Hubei Baidu Chemical Co., Ltd

Tel: 13627137652
Fax: 027-59223020
Email: 1438180055@qq.com
Country: China
ProdList: 9994
Advantage: 58

Less

View Lastest Price from (-)-ANABASINE manufacturers

Anhui Rencheng Technology Co., Ltd

Product: Anabasine 494-52-0
Price: US $1.00-90.00/KG
Min. Order: 0.5KG
Purity: >99%
Supply Ability: 20tons
Release date: 2021-07-28

Zhuozhou Wenxi import and Export Co., Ltd

Product: (-)-ANABASINE 494-52-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-10

Career Henan Chemical Co

Product: Anabasine 494-52-0
Price: US $8.00/KG
Min. Order: 1g
Purity: ≥98%
Supply Ability: kg--tons
Release date: 2020-03-05

494-52-0, (-)-ANABASINERelated Search:

Protionamide Sulfoxide (-)-ANABASINE AKOS 213-73 (S)-3-(3,4,5,6-TETRAHYDRO-2H-[2,3']BIPYRIDINYL-1-YL)-PROPIONIC ACID METHYL ESTER (R,S)-N-NITROSOANABASINE 4-OXO-4-(S)-3,4,5,6-TETRAHYDRO-2H-[2,3']BIPYRIDINYL-1-YL-BUTYRIC ACID (+/-)-ANABASINE DIPICRATE (-)-ANABASINE N-Methylanabasine 4-METHOXY-3-[(S)-1-(3,4,5,6-TETRAHYDRO-2H-[2,3']BIPYRIDINYL-1-YL)METHYL]-BENZALDEHYDE (S)-2-(3,4,5,6-TETRAHYDRO-2H-[2,3']BIPYRIDINYL-1-YL)-ETHANOL (+)-Anabasinehydrochloride AKOS 213-74 3-[(2S)-PIPERIDIN-2-YL]PYRIDINE HYDROCHLORIDE ANABASINE SULFATE

(-)-anabasin

(s)-3-(2-piperidinyl)pyridine

ANOBASINE

L(-)-Anabasine,90%

(2S)-3-(2-Piperidinyl)-pyridine

(-)-2-(3'-Pyridyl)piperidine

L(-)-Anabasine, 90% 500MG

(S)-(-)-2-(3-PYRIDYL)PIPERIDINE

(S)-1,2,3,4,5,6-HEXAHYDRO-[2,3']BIPYRIDINYL

NEONICOTINE

L(-)-NEONICOTINE

L(-)-ANABASINE

L-ANABASINE

2-(3-PYRIDYL)PIPERIDINE

(-)-ANABASINE

ANABASINE

Nicotine USP RC G

3-(2S)-2-Piperidinyl-pyridine

Neonikoti

2-(3-pyridyl)-piperidin

3-(2-Piperidinyl)pyridine

3-(2-piperidyl)-pyridin

Anabasin

Anabazin

l-3-(2’-piperidyl)pyridine

L-3-(2'-Piperidyl)pyridine

Neonikotin

Piperidine, 2-(3-pyridyl)-

Pyridine, 3-(2-piperidyl)-

pyridine,3-(2-pyridyl)piperidine

S-(-)-Anabasine

(S)-3-(Piperidin-2-yl)pyridine+

PYRIDINE,3-(2S)-2-PIPERIDINYL-,

3-((S)-piperidin-2-yl)pyridine

Nicotine Related Compound G (20 mg)

(S)-Anabasine, > 70% ee DISCONTINUED. Please see A637170

(S)-Anabasine, > 98% ee

Nicotine Impurity G

Nicotine USP Related Compound G

3-[(2S)-piperidin-2-yl]pyridine (anabasine)

(S)-Snabasine

Rizatriptan Impurity 3-d6 Benzoate Salt（Rizatriptan EP Impurity C-d6 Benzoate Salt）

494-52-0

Aromatics Compounds

Aromatics

Chiral Reagents

Nicotine Derivatives