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2-BROMO-4-(TRIFLUOROMETHYL)PHENOL

Product Name
2-BROMO-4-(TRIFLUOROMETHYL)PHENOL
CAS No.
81107-97-3
Chemical Name
2-BROMO-4-(TRIFLUOROMETHYL)PHENOL
Synonyms
BUTTPARK 180\07-84;3-Bromo-4-hydroxybenzotrifluoride;2-BROMO-4-(TRIFLUOROMETHYL)PHENOL;Phenol, 2-bromo-4-(trifluoromethyl)-;2-Bromo-4-(trifluoromethyl)phenol >2-Bromo-4-(trifluoromethyl)phenol, 2-Bromo-alpha,alpha,alpha-trifluoro-p-cresol
CBNumber
CB0131207
Molecular Formula
C7H4BrF3O
Formula Weight
241.01
MOL File
81107-97-3.mol
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2-BROMO-4-(TRIFLUOROMETHYL)PHENOL Property

Boiling point:
196.7±35.0 °C(Predicted)
Density 
1.752±0.06 g/cm3(Predicted)
refractive index 
1.4960 to 1.5000
storage temp. 
Inert atmosphere,Room Temperature
pka
7.03±0.18(Predicted)
form 
Liquid
color 
Brown
λmax
317nm(CH3CN)(lit.)
CAS DataBase Reference
81107-97-3
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Safety

HS Code 
2908190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B4492
Product name
2-Bromo-4-(trifluoromethyl)phenol
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$76
Updated
2025/07/31
TCI Chemical
Product number
B4492
Product name
2-Bromo-4-(trifluoromethyl)phenol
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$222
Updated
2025/07/31
TRC
Product number
B695953
Product name
2-Bromo-4-(trifluoromethyl)phenol
Packaging
250mg
Price
$55
Updated
2021/12/16
Oakwood
Product number
023859
Product name
2-Bromo-4-(trifluoromethyl)phenol
Purity
98%
Packaging
250mg
Price
$10
Updated
2021/12/16
Oakwood
Product number
023859
Product name
2-Bromo-4-(trifluoromethyl)phenol
Purity
98%
Packaging
1g
Price
$11
Updated
2021/12/16
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2-BROMO-4-(TRIFLUOROMETHYL)PHENOL Chemical Properties,Usage,Production

Chemical Properties

Light brown liquid

Synthesis

402-45-9

81107-97-3

The general procedure for synthesizing 2-bromo-4-trifluoromethylphenol from p-trifluoromethylphenol is as follows: 32 g of p-trifluoromethylphenol was dissolved in 200 mL of dichloromethane. An equimolar amount of bromine was slowly added dropwise under cooling conditions, and the dropwise process lasted about 2 hours. After the dropwise addition was completed, the reaction mixture was continued to be stirred at room temperature for 12 hours. Upon completion of the reaction, the reaction system was washed with saturated sodium bicarbonate solution to neutral. Subsequently, the organic phase was dried and the solvent was removed by distillation to give 40 g of a thick liquid product. This thick liquid is the target compound 2-bromo-4-trifluoromethylphenol.

References

[1] Tetrahedron, 2003, vol. 59, # 34, p. 6545 - 6558
[2] Patent: WO2009/89192, 2009, A1. Location in patent: Page/Page column 30-31
[3] Chemistry - A European Journal, 2012, vol. 18, # 11, p. 3286 - 3291
[4] Chemical and Pharmaceutical Bulletin, 1996, vol. 44, # 4, p. 734 - 745
[5] Tetrahedron Letters, 2001, vol. 42, # 45, p. 8093 - 8096

2-BROMO-4-(TRIFLUOROMETHYL)PHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BROMO-4-(TRIFLUOROMETHYL)PHENOL Suppliers

Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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84
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
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57
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
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1670
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56
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
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0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2809
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
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56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
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66
Beijing Ouhe Technology Co., Ltd
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010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
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12000
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JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
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60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
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View Lastest Price from 2-BROMO-4-(TRIFLUOROMETHYL)PHENOL manufacturers

Career Henan Chemical Co
Product
2-BROMO-4-(TRIFLUOROMETHYL)PHENOL 81107-97-3
Price
US $5.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-01-12