3-Bromo-4-methoxybenzonitrile
- Product Name
- 3-Bromo-4-methoxybenzonitrile
- CAS No.
- 117572-79-9
- Chemical Name
- 3-Bromo-4-methoxybenzonitrile
- Synonyms
- AKOS B004290;BUTTPARK 87\07-61;2-Bromo-4-cyanoanisole;3-Bromo-p-anisyl cyanide;Phloroglucinol Impurity 229;3-BROMO-4-METHOXYBENZONITRILE;3-Bromo-4-methoxylbenzonitrile;3-Bromo-4-methoxy-carbonitrile;3-Bromo-4-methoxybenzonitrile>Benzonitrile, 3-bromo-4-methoxy-
- CBNumber
- CB5139596
- Molecular Formula
- C8H6BrNO
- Formula Weight
- 212.04
- MOL File
- 117572-79-9.mol
3-Bromo-4-methoxybenzonitrile Property
- Melting point:
- 122-124 °C (lit.)
- Boiling point:
- 282.8±20.0 °C(Predicted)
- Density
- 1.56±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in methanol.
- form
- powder to crystal
- color
- White to Light yellow to Light orange
- BRN
- 3246576
- CAS DataBase Reference
- 117572-79-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38-52
- Safety Statements
- 26-36
- RIDADR
- 3439
- WGK Germany
- 3
- Hazard Note
- Harmful/Irritant
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29269090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B3124
- Product name
- 3-Bromo-4-methoxybenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $48
- Updated
- 2025/07/31
- Product number
- B711060
- Product name
- 3-Bromo-4-methoxybenzonitrile
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- OR2200
- Product name
- 3-Bromo-4-methoxybenzonitrile
- Packaging
- 1g
- Price
- $52
- Updated
- 2021/12/16
- Product number
- FB55225
- Product name
- 2-Bromo-4-cyanoanisole
- Packaging
- 2g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FB55225
- Product name
- 2-Bromo-4-cyanoanisole
- Packaging
- 5G
- Price
- $120
- Updated
- 2021/12/16
3-Bromo-4-methoxybenzonitrile Chemical Properties,Usage,Production
Chemical Properties
Off-white powder
Uses
3-Bromo-4-methoxybenzonitrile is used to prepare 3-bromo-2-iodo-4-methoxy-benzonitrile. It is also used as pharmaceutical intermediates.
Synthesis
2315-86-8
74-88-4
117572-79-9
The reaction was carried out with 3-bromo-4-hydroxybenzonitrile (5.0 g, 25.3 mmol), potassium carbonate (7.0 g, 50.1 mmol) and iodomethane (3.9 g, 27.8 mmol) in acetonitrile (20 mL) with stirring for 6 h at 25 °C. The reaction was carried out by thin layer chromatography (TLC). The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming the completion of the reaction, the reaction mixture was subjected to liquid-liquid separation between ethyl acetate (100 mL) and water (30 mL). The organic phase was collected, washed with brine (20 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure to obtain the crude product. The crude product was purified by fast column chromatography on silica gel to afford 3-bromo-4-methoxybenzenecarbonitrile (4.8 g, 22.6 mmol) in 89% yield using a hexane solution of 30% ethyl acetate as eluent.
References
[1] Patent: WO2017/11590, 2017, A1. Location in patent: Paragraph 00409
[2] Patent: US2005/153877, 2005, A1. Location in patent: Page/Page column 122
3-Bromo-4-methoxybenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
3-Bromo-4-methoxybenzonitrile Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 847-367-3680
- Fax
- 847-367-3681
- sales@arkpharminc.com
- Country
- United States
- ProdList
- 1670
- Advantage
- 56
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2809
- Advantage
- 65
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
View Lastest Price from 3-Bromo-4-methoxybenzonitrile manufacturers
- Product
- 3-Bromo-4-methoxybenzonitrile 117572-79-9
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 334
- Release date
- 2019-09-01