Uses Description Application Description References
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Anisic acid

Uses Description Application Description References
Product Name
Anisic acid
CAS No.
100-09-4
Chemical Name
Anisic acid
Synonyms
Anisic;p Acid;FEMA 3945;p-Anissure;Anisic aci;ANISIC ACID;draconicacid;'LGC' (2407);Draconic acid;p-Anisc Acid
CBNumber
CB6746524
Molecular Formula
C8H8O3
Formula Weight
152.15
MOL File
100-09-4.mol
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Anisic acid Property

Melting point:
182-185 °C(lit.)
Boiling point:
275 °C
Density 
1.385
FEMA 
3945 | 4-METHOXYBENZOIC ACID
refractive index 
1.571-1.576
Flash point:
185 °C
storage temp. 
Store below +30°C.
solubility 
H2O: soluble2500 parts
pka
4.50(at 25℃)
form 
Powder
color 
White to slightly gray-beige
PH
3-4 (0.3g/l, H2O, 20℃)
Water Solubility 
Soluble in water at 20°C 0.3g/L. Soluble in alcohol, ethyl acetate and ether.
JECFA Number
883
Merck 
14,666
BRN 
508910
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
ZEYHEAKUIGZSGI-UHFFFAOYSA-N
CAS DataBase Reference
100-09-4(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 4-methoxy-(100-09-4)
EPA Substance Registry System
Benzoic acid, 4-methoxy- (100-09-4)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-24/25
WGK Germany 
1
RTECS 
BZ4395000
Autoignition Temperature
185 °C
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29189090
Toxicity
LD50 orally in Rabbit: > 5000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
117390
Product name
4-Methoxybenzoic acid
Purity
ReagentPlus , 99%
Packaging
5g
Price
$14.7
Updated
2021/03/22
Sigma-Aldrich
Product number
117390
Product name
4-Methoxybenzoic acid
Purity
ReagentPlus , 99%
Packaging
100g
Price
$40.5
Updated
2021/03/22
Sigma-Aldrich
Product number
W394512
Product name
p-Anisic acid
Purity
natural, 99%, FG
Packaging
100 g
Price
$75
Updated
2021/03/22
Sigma-Aldrich
Product number
8.05971
Product name
4-Methoxybenzoic acid
Purity
for synthesis
Packaging
250 g
Price
$92.13
Updated
2021/03/22
Sigma-Aldrich
Product number
8.05971
Product name
4-Methoxybenzoic acid
Purity
for synthesis
Packaging
1 kg
Price
$208.12
Updated
2021/03/22
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Anisic acid Chemical Properties,Usage,Production

Uses

4-Methoxybenzoic acid was used in oxidation and reduction of cytochrome c in solution through different self-assembled monolayers on gold electrodes using cyclic voltammetry. It is also the sole source of carbon and energy for growth in the cultures of Nocardia sp. DSM 1069.

Description

Anisic acid or methoxybenzoic acid is an organic compound which is a carboxylic acid. P-Anisic acid, known also as 4-methoxybenzoic acid or Draconic acid, which is a methoxybenzoic acid substituted with a methoxy group at position C-4, and P-Anisic acid is an organic acid with sweet flavor. It is one of the isomers (m-anisic acid, and o-anisic acid) of anisic acid. The term anisic acid is often used to describe p-anisic acid and P-anisic acid is produced through the oxidation of p-cresyl-methyl ether. P-Anisic acid is a carboxylic acid found naturally in anise, a flowering plant in the family Apiaceae. P-Anisic acid exists as a white crystalline solid which is insoluble in water, highly soluble in alcohols, and soluble in ether and ethyl acetate.

Application

P-Anisic acid is used mostly as photographic chemicals and dye intermediate. It is also used as fragrance and flavoring agent for pharmaceuticals, drug, antimicrobial (against bacterias, mold and yeast), repellent, ovicide, antirheumatic agent, synthetic flavoring agent in foods, lab reagent, fragrance ingredient, and odor masking agent for products, furthermore, it is also used for the preparation of p-aniosylchloride.
P-Anisic acid has antiseptic properties and is typically used as a preservative in cosmetics and skin care products. Because P-Anisic acid is derived from anise, a flowering plant native, it is safe ingredients in cosmetics to replace potentially toxic preservatives like parabens in some natural or organic skin care products.

Description

P-anisic acid, known also as 4-methoxybenzoic acid or draconic acid, is an organic acid with sweet flavor. It is one of the isomers (m-anisic acid, and o-anisic acid) of anisic acid. The term anisic acid is often used to describe p-anisic acid. P-anisic acid is produced through the oxidation of p-cresyl-methyl ether.
P-anisic acid is used mostly as photographic chemicals and dye intermediate. It is also used as fragrance and flavoring agent for pharmaceuticals, drug, antimicrobial (against bacterias, mold and yeast), repellent, ovicide, antirheumatic agent, synthetic flavoring agent in foods, lab reagent, fragrance ingredient, and odor masking agent for products. It is also used for the preparation of p-aniosylchloride. Furthermore, it is marketed as preservative-free for surfactant based formulations, such as shampoos, shower gels, and bubble baths.

References

[1] Michael Ash (2004) Handbook of Preservatives
[2] Asim Kumar Mukhopadhyay (2004) Industrial Chemical Cresols and Downstream Derivatives
[3] https://en.wikipedia.org/wiki/P-Anisic_acid

Chemical Properties

white powder

Chemical Properties

4-Methoxybenzoic acid is practically odorless.

Uses

Intermediates of Liquid Crystals

Definition

ChEBI: A methoxybenzoic acid substituted with a methoxy group at position C-4.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 25, p. 973, 1988 DOI: 10.1002/jhet.5570250351
Tetrahedron Letters, 34, p. 4603, 1993 DOI: 10.1016/S0040-4039(00)60635-4

Safety Profile

Poison by subcutaneous route.When heated to decomposition it emits acrid smoke andirritating vapors.

Purification Methods

Crystallise p-anisic acid from EtOH, water, EtOH/water or toluene. The S-benzylisothiuronium salt has m 189o (from EtOH). [Beilstein 10 II 91, 10 III 280, 10 IV 346.]

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Anisic acid Suppliers

BeiLi Technology (Chongqing) Co., Ltd.
Tel
023-68980600-
Email
sales@beili.com
Country
China
ProdList
18
Advantage
50
Hebei Yingong New Material Technology Co.,Ltd.
Tel
Email
lisa@hbyingong.com
Country
China
ProdList
22
Advantage
58
Shijiazhuang Suking Biotechnology Co .,Ltd.
Tel
173-1858-6295
Fax
17318586295
Email
sales1@sxbiology.com
Country
China
ProdList
181
Advantage
58
Shanghai Pengsuo Biochemical Technology Co., Ltd.
Tel
021-59118555-
Fax
021-59119222
Email
pengsuochem@163.com
Country
China
ProdList
3305
Advantage
55
Hebei mo Jin biotechnology co., ltd
Tel
Email
angelia@hbmojin.com
Country
China
ProdList
1293
Advantage
58
Tianjin fengyuan biology science and technology co., ltd
Tel
022-1810010-2397
Email
fy.ella@fengyuanbiotech.com
Country
China
ProdList
20
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40264
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066-400;021-60496031
Fax
021-55660885
Email
sales@jonln.com;sales@jonln.com
Country
China
ProdList
1999
Advantage
65
Alfa Aesar
Tel
400-610-6006; 021-67582000
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30159
Advantage
84
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View Lastest Price from Anisic acid manufacturers

Shanxi Lianxu New Material Co., LTD
Product
Anisic acid 100-09-4
Price
US $100.00/KG
Min. Order
1KG
Purity
99.9%
Supply Ability
1000kg/month
Release date
2021-10-27
Hanhong Medicine Technology (Hubei) Co., Ltd.
Product
Anisic acid 100-09-4
Price
US $50.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-05-21
Hebei Crovell Biotech Co Ltd
Product
p-Anisic acid 100-09-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
30 ton
Release date
2021-06-18

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