ChemicalBook > CAS DataBase List > 4-(Trifluoromethoxy)aniline

4-(Trifluoromethoxy)aniline

Product Name
4-(Trifluoromethoxy)aniline
CAS No.
461-82-5
Chemical Name
4-(Trifluoromethoxy)aniline
Synonyms
Riluzole Related CoMpound A;AKOS B016000;4-(TrifluoroMe;Riluzole USP RC A;TIMTEC-BB SBB001667;Riluzole Impurity 10;Trifluoromethoxyaniline;4-Trifluoroethoxyaniline;4-trifluoromethoxyaniune;4-(Trifluormethoxy)anilin
CBNumber
CB3322028
Molecular Formula
C7H6F3NO
Formula Weight
177.12
MOL File
461-82-5.mol
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4-(Trifluoromethoxy)aniline Property

Boiling point:
73-75 °C10 mm Hg(lit.)
Density 
1.32 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.463(lit.)
Flash point:
177 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka
3.75±0.10(Predicted)
form 
Liquid
color 
Clear colorless to yellow
Specific Gravity
1.310
BRN 
2090209
Stability:
Hygroscopic
InChI
InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2
InChIKey
XUJFOSLZQITUOI-UHFFFAOYSA-N
SMILES
C1(N)=CC=C(OC(F)(F)F)C=C1
CAS DataBase Reference
461-82-5(CAS DataBase Reference)
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Safety

Hazard Codes 
T,Xi,Xn
Risk Statements 
24/25-33-38-41-36/37/38-20/21/22
Safety Statements 
26-36/37/39-45-36
RIDADR 
UN 2941 6.1/PG 3
WGK Germany 
2
Hazard Note 
Toxic
HazardClass 
IRRITANT, TOXIC
HazardClass 
6.1
PackingGroup 
III
HS Code 
29222900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H310Fatal in contact with skin

H315Causes skin irritation

H318Causes serious eye damage

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
337056
Product name
4-(Trifluoromethoxy)aniline
Purity
98%
Packaging
5g
Price
$46.8
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR3132
Product name
Riluzole Related Compound A
Purity
pharmaceutical secondary standard, certified reference material
Packaging
50MG
Price
$534
Updated
2024/03/01
Sigma-Aldrich
Product number
1604348
Product name
Riluzole Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$1210
Updated
2024/03/01
TCI Chemical
Product number
T1345
Product name
4-(Trifluoromethoxy)aniline
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
T1345
Product name
4-(Trifluoromethoxy)aniline
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$55
Updated
2024/03/01
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4-(Trifluoromethoxy)aniline Chemical Properties,Usage,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

4-(Trifluoromethoxy)aniline was used in the synthesis of:

  • side-group liquid-crystalline polymethacrylates with fluorine-containing mesogens
  • derivatives of 3-(quinolin-3-yl)acrylates
  • series of novel Shiff bases, via condensation with pyridinecarboxaldehydes in the presence of molecular sieves

Uses

4-(Trifluoromethoxy)aniline is used in the synthesis of anticancer agents and antitumor medicaments. Also, its an intermediate in the production of labelled Riluzole, a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.

4-(Trifluoromethoxy)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(Trifluoromethoxy)aniline Suppliers

Qi-Chem Co., Ltd.
Tel
0411-88165951 13601035838
Fax
0411-87406949
Email
marketing@qi-chem.com
Country
China
ProdList
150
Advantage
58
Nanjing XiLang Chemical Products Co., Ltd.
Tel
18936048580
Email
chemxilang@163.com
Country
China
ProdList
3995
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58
CHANGZHOU FLUORIDE CHEMICAL CO.,LTD
Tel
0086-519-89892883 15995021858
Fax
0519-85227531
Email
info@fluoridechem.com
Country
China
ProdList
80
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58
Jinkai (Liaoning) Life Technology Co., LTD
Tel
021-64272437
Email
customer-service@kingchem.com
Country
China
ProdList
41
Advantage
58
SHANG FLUORO
Tel
021-65170832 15601903708
Email
qinba_1@163.com
Country
China
ProdList
374
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60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
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View Lastest Price from 4-(Trifluoromethoxy)aniline manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
4-(Trifluoromethoxy)aniline 461-82-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-08
Hebei Weibang Biotechnology Co., Ltd
Product
4-(Trifluoromethoxy)aniline 461-82-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-30
Hebei Yanxi Chemical Co., Ltd.
Product
4-(Trifluoromethoxy)aniline 461-82-5
Price
US $20.00-7.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
30 tons
Release date
2023-10-10

461-82-5, 4-(Trifluoromethoxy)anilineRelated Search:


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