4-(Trifluoromethoxy)aniline

Product Name: 4-(Trifluoromethoxy)aniline
CAS No.: 461-82-5
Chemical Name: 4-(Trifluoromethoxy)aniline
Synonyms: Riluzole Related CoMpound A;AKOS B016000;4-(TrifluoroMe;Riluzole USP RC A;TIMTEC-BB SBB001667;Riluzole Impurity 10;Trifluoromethoxyaniline;4-Trifluoroethoxyaniline;4-trifluoromethoxyaniune;4-(Trifluormethoxy)anilin
CBNumber: CB3322028
Molecular Formula: C7H6F3NO
Formula Weight: 177.12
MOL File: 461-82-5.mol

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4-(Trifluoromethoxy)aniline Property

Boiling point:: 73-75 °C10 mm Hg(lit.)
Density: 1.32 g/mL at 20 °C(lit.)
refractive index: n20/D 1.463(lit.)
Flash point:: 177 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka: 3.75±0.10(Predicted)
form: Liquid
color: Clear colorless to yellow
Specific Gravity: 1.310
BRN: 2090209
Stability:: Hygroscopic
InChI: InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2
InChIKey: XUJFOSLZQITUOI-UHFFFAOYSA-N
SMILES: C1(N)=CC=C(OC(F)(F)F)C=C1
CAS DataBase Reference: 461-82-5(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xi,Xn
Risk Statements: 24/25-33-38-41-36/37/38-20/21/22
Safety Statements: 26-36/37/39-45-36
RIDADR: UN 2941 6.1/PG 3
WGK Germany: 2
Hazard Note: Toxic
HazardClass: IRRITANT, TOXIC
HazardClass: 6.1
PackingGroup: III
HS Code: 29222900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H310Fatal in contact with skin

H315Causes skin irritation

H318Causes serious eye damage

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 337056
Product name: 4-(Trifluoromethoxy)aniline
Purity: 98%
Packaging: 5g
Price: $46.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR3132
Product name: Riluzole Related Compound A
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 50MG
Price: $534
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1604348
Product name: Riluzole Related Compound A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25mg
Price: $1210
Updated: 2024/03/01

TCI Chemical

Product number: T1345
Product name: 4-(Trifluoromethoxy)aniline
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $20
Updated: 2024/03/01

TCI Chemical

Product number: T1345
Product name: 4-(Trifluoromethoxy)aniline
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $55
Updated: 2024/03/01

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4-(Trifluoromethoxy)aniline Chemical Properties,Usage,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

4-(Trifluoromethoxy)aniline was used in the synthesis of:

side-group liquid-crystalline polymethacrylates with fluorine-containing mesogens
derivatives of 3-(quinolin-3-yl)acrylates
series of novel Shiff bases, via condensation with pyridinecarboxaldehydes in the presence of molecular sieves

Uses

4-(Trifluoromethoxy)aniline is used in the synthesis of anticancer agents and antitumor medicaments. Also, its an intermediate in the production of labelled Riluzole, a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.

4-(Trifluoromethoxy)aniline Preparation Products And Raw materials

Raw materials

4-(TRIFLUOROMETHOXY)BENZAMIDE 4-(Trifluoromethoxy)nitrobenzene Potassium hydroxide

Preparation Products

Triflumuron Riluzole 5-[4-(TRIFLUOROMETHOXY)PHENYL]-2-FURALDEHYDE

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4-(Trifluoromethoxy)aniline Suppliers

Belgium 2 Canada 1 China 451 Europe 4 France 2 Germany 10 India 23 Italy 1 Japan 5 Jordan 1 Russia 2 Slovakia 1 Switzerland 2 Ukraine 2 United Kingdom 25 United States 42 Global 574

Merck Millipore

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Email: ccc@merckgroup.com
Country: Germany
ProdList: 2008
Advantage: 58

CHEMOS GmbH & Co. KG

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Email: chemos@chemos.de
Country: Germany
ProdList: 6727
Advantage: 58

Dr. Ehrenstorfer GmbH

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Email: info@analytical-standards.com
Country: Germany
ProdList: 5545
Advantage: 66

ABCR GmbH & CO. KG

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Email: info@abcr.de
Country: Germany
ProdList: 6831
Advantage: 75

PARAGOS

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Email: info@paragos.com
Country: Germany
ProdList: 6371
Advantage: 39

Service Chemical Inc.

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Email: sales@chemos-group.com
Country: Germany
ProdList: 6350
Advantage: 71

Merck Schuchardt OHG

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Email: schuchardt-vertrieb@merck.de
Country: Germany
ProdList: 5827
Advantage: 74

AKos Consulting & Solutions GmbH

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Email: akos@akosgmbh.de
Country: Germany
ProdList: 6717
Advantage: 72

Lanxess Deutschland GmbH

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Country: Germany
ProdList: 1267
Advantage: 81

ChemCollect GmbH

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Email: contact@chemcollect.de
Country: Germany
ProdList: 6214
Advantage: 54

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View Lastest Price from 4-(Trifluoromethoxy)aniline manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: 4-(Trifluoromethoxy)aniline 461-82-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-08

Hebei Weibang Biotechnology Co., Ltd

Product: 4-(Trifluoromethoxy)aniline 461-82-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-30

Hebei Yanxi Chemical Co., Ltd.

Product: 4-(Trifluoromethoxy)aniline 461-82-5
Price: US $20.00-7.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 30 tons
Release date: 2023-10-10

461-82-5, 4-(Trifluoromethoxy)anilineRelated Search:

4-Methoxyphenylacetone 4'-(Trifluoromethoxy)acetophenone o-Anisaldehyde Anisole (Trifluoromethoxy)benzene 3-Methoxybenzaldehyde 4-(Trifluoromethoxy)chlorobenzene 2-(Trifluoromethoxy)aniline 4-Aminobenzotrifluoride (3-Methoxyphenyl)acetonitrile 4-Methoxyphenylacetic acid 4-Methoxybenzylchloride p-Trifluoromethoxy phenol 3-(Trifluoromethoxy)aniline Trimethyl phosphite 2-Fluoroaniline Aniline 4-Fluoroaniline

Riluzole Related Compound A (25 mg) (4-trifluoromethoxyaniline)

4-(TrifluoroMethoxy)aniline, 99+% 2.5GR

Riluzole Related CoMpound A

For trifluoromethoxy aniline

4- threedifluoro Methoxyaniline

4-TrifluoroMethoxyaniline, 97+%

The trifluoro Methoxy aniline

4-(TrifluoroMe

4-(Trifluormethoxy)anilin

4-(TRIFLUOROMETHOXY)ANILINE 99.5+%

4-(trifluoromethoxy)aniline,2-(trifluoromethoxy)benzenamine

Benzenamine, 4-(trifluoromethoxy)-

4-(Trifluoromethoxy)aniline,α,α,α-Trifluoro-p-anisidine

AMino TrifluoroMethoxybenzene

4-Amino-alpha,alpha,alpha-trifluoroanisole

4-Trifluoronethoxyaniline

Riluzole USP Related Compound A

Riluzole Impurity 10

ALPHA,ALPHA,ALPHA-TRIFLUORO-P-ANISIDINE

AKOS B016000

4-(TRIFLUOROMETHOXY)ANILINE

4-TRIFLUOROMETHOXY-PHENYLAMINE

TIMTEC-BB SBB001667

4-Trifluoroethoxyaniline

4-trifluoromethoxyaniune

p-Trifluoromethoxyaniline

p-Aminotrifluoromethoxybenzene

P-Aminotrifluoromethpxybenzene

4-Aminotrifluoromethoxybenzene

4-(Trifluoromethoxy)aniline, 99+%

4-TRIFLUORO METHOXYLAMINE

α,α,α-trifluoro-p-anisidine

4-(Trifluoromethoxy)aniline 98%

4-(Trifluoromethoxy)aniline98%

4-(Trifluoromethoxy)aminobenzene

4-(trifluoromethoxy)benzenaime

Riluzole USP RC A

Trifluoromethoxyaniline

4-(Trifluomethoxy) Aniline

Riluzole Related Compound A (4-trifluoromethoxyaniline) (1604348)

461-82-5

462-28-5

117528-59-4

C7H5F3NO

CF3OC6H4NH2

Organic Building Blocks

Nitrogen Compounds

ARYL HALIDE

AMINE

Building Blocks

Amines

C7

Building Blocks

C7

Chemical Synthesis

Nitrogen Compounds

Organic Building Blocks

Pyridines