ChemicalBook > CAS DataBase List > 4-(Trifluoromethoxy)aniline
4-(Trifluoromethoxy)aniline
- Product Name
- 4-(Trifluoromethoxy)aniline
- CAS No.
- 461-82-5
- Chemical Name
- 4-(Trifluoromethoxy)aniline
- Synonyms
- Riluzole Related CoMpound A;AKOS B016000;4-(TrifluoroMe;Riluzole USP RC A;TIMTEC-BB SBB001667;Riluzole Impurity 10;Trifluoromethoxyaniline;4-Trifluoroethoxyaniline;4-trifluoromethoxyaniune;4-(Trifluormethoxy)anilin
- CBNumber
- CB3322028
- Molecular Formula
- C7H6F3NO
- Formula Weight
- 177.12
- MOL File
- 461-82-5.mol
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4-(Trifluoromethoxy)aniline Property
- Boiling point:
- 73-75 °C10 mm Hg(lit.)
- Density
- 1.32 g/mL at 20 °C(lit.)
- refractive index
- n20/D 1.463(lit.)
- Flash point:
- 177 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- pka
- 3.75±0.10(Predicted)
- form
- Liquid
- color
- Clear colorless to yellow
- Specific Gravity
- 1.310
- BRN
- 2090209
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2
- InChIKey
- XUJFOSLZQITUOI-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(OC(F)(F)F)C=C1
- CAS DataBase Reference
- 461-82-5(CAS DataBase Reference)
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Safety
- Hazard Codes
- T,Xi,Xn
- Risk Statements
- 24/25-33-38-41-36/37/38-20/21/22
- Safety Statements
- 26-36/37/39-45-36
- RIDADR
- UN 2941 6.1/PG 3
- WGK Germany
- 2
- Hazard Note
- Toxic
- HazardClass
- IRRITANT, TOXIC
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29222900
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H310Fatal in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 337056
- Product name
- 4-(Trifluoromethoxy)aniline
- Purity
- 98%
- Packaging
- 5g
- Price
- $46.8
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- PHR3132
- Product name
- Riluzole Related Compound A
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 50MG
- Price
- $534
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 1604348
- Product name
- Riluzole Related Compound A
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 25mg
- Price
- $1210
- Updated
- 2024/03/01
TCI Chemical
- Product number
- T1345
- Product name
- 4-(Trifluoromethoxy)aniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $20
- Updated
- 2024/03/01
TCI Chemical
- Product number
- T1345
- Product name
- 4-(Trifluoromethoxy)aniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $55
- Updated
- 2024/03/01
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4-(Trifluoromethoxy)aniline Chemical Properties,Usage,Production
Chemical Properties
CLEAR YELLOW LIQUID
Uses
4-(Trifluoromethoxy)aniline was used in the synthesis of:
- side-group liquid-crystalline polymethacrylates with fluorine-containing mesogens
- derivatives of 3-(quinolin-3-yl)acrylates
- series of novel Shiff bases, via condensation with pyridinecarboxaldehydes in the presence of molecular sieves
Uses
4-(Trifluoromethoxy)aniline is used in the synthesis of anticancer agents and antitumor medicaments. Also, its an intermediate in the production of labelled Riluzole, a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.
4-(Trifluoromethoxy)aniline Preparation Products And Raw materials
Raw materials
Preparation Products
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4-(Trifluoromethoxy)aniline Suppliers
- Tel
- --
- Fax
- --
- ccc@merckgroup.com
- Country
- Germany
- ProdList
- 2010
- Advantage
- 58
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View Lastest Price from 4-(Trifluoromethoxy)aniline manufacturers
Henan Fengda Chemical Co., Ltd
- Product
- 4-(Trifluoromethoxy)aniline 461-82-5
- Price
- US $8.00-0.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-22
Hebei Yanxi Chemical Co., Ltd.
- Product
- 4-(Trifluoromethoxy)aniline 461-82-5
- Price
- US $20.00-7.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 30 tons
- Release date
- 2023-10-10
Hebei Mojin Biotechnology Co., Ltd
- Product
- 4-(Trifluoromethoxy)aniline 461-82-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-11-01
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