ChemicalBook > CAS DataBase List > 2-Fluoroaniline

2-Fluoroaniline

Product Name
2-Fluoroaniline
CAS No.
348-54-9
Chemical Name
2-Fluoroaniline
Synonyms
2-fluroaniline;O-FLUOROANILINE;2-Fluorobenzenamine;AKOS 91139;2-Fluoranilin;2-FLUOROANILINE;FLUOROANILINE-2;AKOS BBS-00003628;1BO-Fluoroaniline;Aniline, 2-fluoro-
CBNumber
CB6853530
Molecular Formula
C6H6FN
Formula Weight
111.12
MOL File
348-54-9.mol
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2-Fluoroaniline Property

Melting point:
-29 °C
Boiling point:
182-183 °C(lit.)
Density 
1.151 g/mL at 25 °C(lit.)
vapor pressure 
1 hPa (20 °C)
refractive index 
n20/D 1.544(lit.)
Flash point:
140 °F
storage temp. 
Store below +30°C.
solubility 
17g/l
form 
Liquid
pka
3.2(at 25℃)
color 
Clear colorless
Specific Gravity
1.151
Water Solubility 
17 g/L (20°C)
BRN 
1524219
CAS DataBase Reference
348-54-9(CAS DataBase Reference)
NIST Chemistry Reference
Benzenamine, 2-fluoro-(348-54-9)
EPA Substance Registry System
o-Fluoroaniline (348-54-9)
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Safety

Hazard Codes 
Xn,T,Xi
Risk Statements 
22-37/38-41-36/38-33-23/24/25
Safety Statements 
26-39-37/39-45-36/37-28
RIDADR 
UN 2941 6.1/PG 3
WGK Germany 
2
RTECS 
BY1390000
Autoignition Temperature
600 °C
Hazard Note 
Toxic/Irritant
TSCA 
T
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214210
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F3401
Product name
2-Fluoroaniline
Purity
≥99%
Packaging
25G
Price
$33.2
Updated
2024/03/01
Sigma-Aldrich
Product number
F3401
Product name
2-Fluoroaniline
Purity
≥99%
Packaging
500G
Price
$344
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20565
Product name
2-Fluoroaniline
Purity
for synthesis
Packaging
100mL
Price
$178
Updated
2024/03/01
Sigma-Aldrich
Product number
F3401
Product name
2-Fluoroaniline
Purity
≥99%
Packaging
100G
Price
$83.4
Updated
2022/05/15
TCI Chemical
Product number
F0032
Product name
2-Fluoroaniline
Purity
>99.0%(GC)
Packaging
25g
Price
$16
Updated
2024/03/01
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2-Fluoroaniline Chemical Properties,Usage,Production

Chemical Properties

2-Fluoroaniline is a clear colorless to brown liquid, toxic, insoluble in water, soluble in ethanol and ether, its vapor and air can form an explosive mixture, which can cause combustion and explosion in case of fire and high heat. Reacts with oxidants. Decomposed by high heat to release toxic gases.

Uses

2-Fluoroaniline (cas# 348-54-9) is a useful reagent for the synthesis of insecticides.

Application

2-Fluoroaniline can be used to synthesize thermosensitive dye FH-102, which is a black thermosensitive dye with wide application and excellent performance. The dye can be used in the production of terminal output printing paper of electronic computer, EEG recording paper, telephone fax paper and transparent thermal film for oil field.

Definition

ChEBI: 2-fluoroaniline is a derivative of aniline in which the hydrogen at position 2 has been substituted by fluorine. It is used as a pharmaceutical intermediate It is a primary arylamine and a fluoroaniline.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 3415, 1984 DOI: 10.1016/S0040-4039(01)91034-2

General Description

Clear liquid with a mild sweet odor. Sinks in and mixes slowly with water.

Air & Water Reactions

Water soluble.

Reactivity Profile

2-Fluoroaniline is a base. Neutralizes acids to form salts plus water in an exothermic reaction. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard

Inhalation or ingestion causes bluish tint to fingernails, lips and ears indicative of cyanosis; headache, drowsiness, and nausea, followed by unconsciousness. Liquid can be absorbed through skin and cause similar symptoms. Contact with eyes causes irritation.

Fire Hazard

Special Hazards of Combustion Products: Irritating and toxic hydrogen fluoride and oxides of nitrogen may form in fires.

Metabolic pathway

2-Fluoro and 3-fluoroanilines are preferentially hydroxylated at the para-position, and 4-fluoroaniline is both p- and o-hydroxylated to a significant extent by rat liver microsomes and is not accompanied with an NIH shift to give 4-hydroxyl-3-fluoroaniline.

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2-Fluoroaniline Suppliers

Changzhou Xinda Biotechnology Co., Ltd
Tel
0519-85519868 18915088878
Email
xiaoweng106108@163.com
Country
China
ProdList
99
Advantage
58
Taizhou Jun Rui Import and Export Co., Ltd.
Tel
0576-88808091 13958565781
Fax
0576-88808091
Email
janney.liu@groundfortune.com
Country
China
ProdList
61
Advantage
55
Ningbo Zhenlei Chemical Co.,ltd.
Tel
0576-88808091 13958565781
Fax
+0576-88203603
Email
shuang.lin@zhenleichem.com
Country
China
ProdList
89
Advantage
58
Shandong Jiuyue Biological Technology Co. LT
Tel
18853316981 18853316981
Email
1214127295@qq.com
Country
China
ProdList
38
Advantage
58
Shandong Mingde Biotechnology Co., Ltd
Tel
15564477061
Email
1397986535@qq.com
Country
China
ProdList
281
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
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View Lastest Price from 2-Fluoroaniline manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
2-Fluoroaniline 348-54-9
Price
US $30.00-10.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-11-23
Henan Fengda Chemical Co., Ltd
Product
2-Fluoroaniline 348-54-9
Price
US $50.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-22
XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
Product
2-Fluoroaniline 348-54-9
Price
US $25.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
50000kg/month
Release date
2022-01-24

348-54-9, 2-FluoroanilineRelated Search:


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