2-Nitrochlorobenzene

Product Name: 2-Nitrochlorobenzene
CAS No.: 88-73-3
Chemical Name: 2-Nitrochlorobenzene
Synonyms: 1-CHLORO-2-NITROBENZENE;ONCB;2-CHLORONITROBENZENE;O-NITROCHLOROBENZENE;ORTHO-CHLORONITROBENZENE;2-cnb;lenvaint-F;oronitrobenzene;2-Chlornitrobenzol;o-Chloronitrobenzen
CBNumber: CB3767980
Molecular Formula: C6H4ClNO2
Formula Weight: 157.55
MOL File: 88-73-3.mol

More

Less

2-Nitrochlorobenzene Property

Melting point:: 31-33 °C (lit.)
Boiling point:: 246 °C (lit.)
Density: 1.348 g/mL at 25 °C (lit.)
vapor density: 5.4 (vs air)
vapor pressure: 0.04 mm Hg ( 25 °C)
refractive index: 1.5520 (estimate)
Flash point:: >230 °F
storage temp.: Store below +30°C.
solubility: alcohol: soluble
form: Fused Crystalline Mass
color: Yellow
PH: 6 (0.4g/l, H2O, 20℃)
explosive limit: 1.15-13.1%(V)
Water Solubility: 0.43 g/L (20 ºC)
Merck: 14,2151
BRN: 509273
Stability:: Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, strong bases, alkali metals.
InChIKey: BFCFYVKQTRLZHA-UHFFFAOYSA-N
CAS DataBase Reference: 88-73-3(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, 1-chloro-2-nitro-(88-73-3)
IARC: 2B (Vol. 65, 123) 2020
EPA Substance Registry System: o-Chloronitrobenzene (88-73-3)

More

Less

Safety

Hazard Codes: T
Risk Statements: 22-24-52-53-52/53
Safety Statements: 36/37/39-45-60-38-28A
RIDADR: UN 1578 6.1/PG 2
WGK Germany: 2
RTECS: CZ0875000
Autoignition Temperature: 500 °F
Hazard Note: Toxic
TSCA: Yes
HazardClass: 6.1
PackingGroup: II
HS Code: 29049085
Hazardous Substances Data: 88-73-3(Hazardous Substances Data)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 185760
Product name: 1-Chloro-2-nitrobenzene
Purity: 99%
Packaging: 250g
Price: $50.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: 185760
Product name: 1-Chloro-2-nitrobenzene
Purity: 99%
Packaging: 1kg
Price: $78.28
Updated: 2025/07/31

TCI Chemical

Product number: C0220
Product name: 2-Chloronitrobenzene
Purity: >99.0%(GC)
Packaging: 25g
Price: $16
Updated: 2025/07/31

TCI Chemical

Product number: C0220
Product name: 2-Chloronitrobenzene
Purity: >99.0%(GC)
Packaging: 500g
Price: $60
Updated: 2025/07/31

TRC

Product number: C367105
Product name: 1-Chloro-2-nitrobenzene
Packaging: 500g
Price: $225
Updated: 2021/12/16

More

Less

2-Nitrochlorobenzene Chemical Properties,Usage,Production

Chemical Properties

yellow solid with a characteristic odour

Uses

Chemical intermediate in manufacture of dyes, picric acid, lumber preservatives, and diaminophenol hydrochloride (a photographic developer)

Uses

1-Chloro-2-nitrobenzene was used in the synthesis of 1-hydroxybenzotriazole derivatives. It is important as a precursor to other compounds due to the two reactive sites present on the molecule.

Uses

Intermediate, especially for dyes.

Production Methods

Nitration of chlorobenzene with mixed acid (30/56/14) typically gives an isomer mix in 98 % yield consisting of 34 – 36 % 2-Nitrochlorobenzene, 63 – 65 % 4- chloronitrobenzene, and only ca. 1 % 3- chloronitrobenzene. The ortho – para ratio of about 0.55 is in sharp contrast to the 1.6 obtained with nitrotoluene isomers. As with the nitration of toluene, much work has been done on isomer control so that the producer might have some flexibility towards the balance of isomer demand. Although no major change in ratio has been achieved, the situation is better for nitrochlorobenzene than nitrotoluenes, because the favored isomer is in much greater demand. In further contrast to the nitration of toluene, the nitration of chlorobenzene in the presence of phosphoric acid decreases the proportion of 4-Nitrochlorobenzene, and the use of phosphoric acid in the presence of a transition-metal catalyst is said to increase the ortho – para ratio to ca. 0.8.

Definition

ChEBI: 1-chloro-2-nitrobenzene is a C-nitro compound that is nitrobenzene in which one of the ortho- hydrogens has been replaced by chlorine. It is a C-nitro compound and a member of monochlorobenzenes.

General Description

Yellow crystals with an aromatic odor. Sinks in water.

Air & Water Reactions

2-Nitrochlorobenzene may be sensitive to prolonged exposure to air and light. Insoluble in water.

Reactivity Profile

O-NITROCHLOROBENZENE is incompatible with strong bases and strong oxidizing agents. 2-Nitrochlorobenzene will react with ammonia.

Hazard

Toxic by inhalation and ingestion. Combustible. Questionable carcinogen.

Health Hazard

INHALATION: Headache, languour, anemia. Irritation of nose and throat, cyanosis, shallow respiration, convulsions, and coma. EYES: Irritation. SKIN: Irritation. INGESTION: Forms methemoglobin giving rise to cyanosis and blood changes.

Flammability and Explosibility

Not classified

Safety Profile

Suspected carcinogen with experimental carcinogenic and neoplastigenic data. Poison by ingestion, skin contact, and probably inhalation. Combustible when exposed to heat or flame. To fight fire, use water, foam. Potentially explosive reaction with ammonia at 160℃/30 bar. When heated to decomposition it emits toxic fumes of Cl-, NOx, and phosgene. See also other chloronitrobenzene entries and NITRO COMPOUNDS of AROMATIC HYDROCARBONS.

Purification Methods

Crystallise it from EtOH, MeOH or pentane (charcoal). [Beilstein 5 IV 721.]

Toxics Screening Level

The Initial Risk Screening Level (IRSL) for 1-chloro-2-nitrobenzene (CAS# 88-73-3) is 0.21 μg/m3 based on an annual averaging time.

2-Nitrochlorobenzene Preparation Products And Raw materials

Raw materials

4-Chloronitrobenzene 2-Nitroaniline Chlorobenzene Copper(I) chloride Hydrochloric acid Nitric acid Dimethyl sulfoxide Sodium hydroxide POTASSIUM NITRITE 1-Chloro-3-nitrobenzene Sulfuric acid

Preparation Products

2-Fluorophenol 4-Chloro-3-nitrobenzenesulfonyl chloride 2-Nitroanisole o-Anisidine N-Methyl-1,2-benzenediamine dihydrochloride Aniline-2-sulfonic acid 4-Chloronitrobenzene 2-Mercaptobenzothiazole 2-Chloro-6-nitrotoluene Guaiacol FAST ORANGE GR SALT 2-Nitrophenol 2-Nitrodiphenylamine 3-Amino-4-hydroxybenzenesulphonamide N-METHYL-2-NITROANILINE Bis(2-nitrophenyl) disulfide o-Phenetidine 2-chlorobenzenediazonium 2-Nitroaniline Pigment Yellow 13 2-Fluoroaniline o-Toluidine Disperse Yellow Se-Fl 2-(4-METHYLPHENYL)-BENZOTHIAZOLE ANILAZINE 2-Aminophenol 2-Chloroaniline 2-CHLOROANILINE HYDROCHLORIDE 2-Mercaptobenzimidazole Domperidone 2-Aminobenzenethiol 1-Fluoro-2-nitrobenzene 2,4-Dinitrochlorobenzene o-Phenylenediamine o-chlorobenzenediazonium chloride, compound with zinc chloride

More

Less

2-Nitrochlorobenzene Suppliers

China 57 Global 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11707
Advantage: 57

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Chengdu Dianchun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

Hubei Zhonglong Kangsheng Fine Chemical Co., Ltd.

Tel: 15926260361
Fax: QQ:1930063008
Email: 1930063008@qq.com
Country: China
ProdList: 988
Advantage: 58

HUNAN CHEMFISH SCIENTIFIC CO.,LTD

Tel: +86-0731-85567275 17788968862
Fax: QQ:3554193828
Email: sales05@chemfish.com
Country: China
ProdList: 7380
Advantage: 58

Wuhan xinyangruihe Chemical Technology Co., Ltd.

Tel: 027-18120580375 18120580375
Fax: 027-83850375
Email: 669797270@qq.com
Country: China
ProdList: 983
Advantage: 58

Anhui bayi chemical co. LTD

Tel: 0552-4928181 13956398811
Fax: 0552-3015301
Email: sales@bayichem.com
Country: China
ProdList: 21
Advantage: 58

88-73-3, 2-NitrochlorobenzeneRelated Search:

2-Chlorobenzyl chloride 2,3,4-TRICHLORONITROBENZENE 2,6-Dichloronitrobenzene 2-Chloroaniline NITROCHLOROBENZENE 1,2,3-Trichlorobenzene 2-Chlorotoluene 4-Nitrophenyl chloroformate Epichlorohydrin 1-Phenyl-2-nitropropene 2-Methylbenzyl chloride 1,2,4-Trichlorobenzene Difluorochloromethane 2,3-Dichloronitrobenzene Nitrochlorobenzene, p-,Nitrochlorobenzene, para,P-NITROCHLOROBENZENE,4-NITROCHLOROBENZENE,PARA NITROCHLOROBENZENE 1-Chloro-3-nitrobenzene TECNAZENE 2-Chloro-3-nitrobenzoic acid

1-CHLORO-2-NITROBENZENE

2-cnb

2-CHLORONITROBENZENE

2-Chloro-1-nitrobenzene

2-NITROCHLOROBENZENE

chloro-1nitro-2benzene

Chloro-o-nitrobenzene

Nitrochlorobenzene, o-

Nitrochlorobenzene, ortho

ONCB

o-nitrochlorobenzene,[liquid]

Ortho Nitrochlorobenzene [ONCB]

2-Chluoronitrobenzene

2-CHLORONITROBENZENE OEKANAL, 250 MG

1-Chloro-2-NitrobenzeneForSynthesis

1-Chloro-2-nitrobenzene, 99+%

2-MONOCHLORONITROBENZENE

ORTHO-CHLORONITROBENZENE

2-Chlornitrobenzol

lenvaint-F

1-NITRO-2-CHLORINE BENZENE

O-CHLORONITROBENZENE

ORTHO NITROCHLOROBENZENE

O-NITROCHLOROBENZENE

1-chloro-2-nitro-benzen

1-Nitro-2-chlorobenzene

o-NITROCHLOROBENZENE pure

benzene,1-chloro-2-nitro-

2-Nitro-1-chlorobenzene

2-Nitrophenyl chloride

o-Chloronitrobenzene Standard

1-Chloro-2-nitrobenzene 5g [88-73-3]

2-Chloronitrobenzene 99%

o-Chloronitrobenzene Standard157.56

1-Chloro-2-nitrobenzol

o-Chloronitrobenzene solution

o-Chloronitrobenzen

2-Chloronitrobenzene, 99.0%(GC)

oronitrobenzene

2-Chloronitrobenzene &gt

2-Chloronitrobenzene,99%

o-Nitrochlorobenzene (ONCB) pure, 99%

Lansoprazole Impurity 49

1-Chloro-2-nitrobenzene in Methanol

1-Chloro-2-nitrobenzene 100 μg/ml Cyclohexane

XA11453500ME1-Chloro-2-nitrobenzenE100μg/mLi

1-Chloro-2-nitrobenzene 100 μg/mL in Methanol

1-Chloro-2-nitrobenzene 10 μg/mL in Methanol

88-73-3

8-73-3

88733

O2NClC6H4

O2NC6H4Cl

Nitrogen Compounds

Organic Building Blocks

Nitro Compounds

Building Blocks

alkyl chloride| nitro-compound