2-Fluorophenol
- Product Name
- 2-Fluorophenol
- CAS No.
- 367-12-4
- Chemical Name
- 2-Fluorophenol
- Synonyms
- 1-Bromo-3-fluorobezene;O-FLUOROPHENOL;uorophenoL;2-Florophenol;2-Flurophenol;2-fluoro-pheno;2-FLUOROPHENOL;o-fluoro-pheno;2-Fluorophenole;2-Fluorophenol f
- CBNumber
- CB0495831
- Molecular Formula
- C6H5FO
- Formula Weight
- 112.1
- MOL File
- 367-12-4.mol
2-Fluorophenol Property
- Melting point:
- 16.1 °C (lit.)
- Boiling point:
- 171-172 °C/741 mmHg (lit.)
- Density
- 1.256 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.511(lit.)
- Flash point:
- 116 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- 37.7g/l
- form
- Liquid
- pka
- 8.73(at 25℃)
- Specific Gravity
- 1.256
- color
- Clear colorless to light yellow-brownish
- Water Solubility
- 80.72g/L(25 ºC)
- BRN
- 1905112
- Stability:
- Stable. Flammable. Incompatible with strong oxidizing agents.
- InChIKey
- HFHFGHLXUCOHLN-UHFFFAOYSA-N
- CAS DataBase Reference
- 367-12-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Phenol, 2-fluoro-(367-12-4)
- EPA Substance Registry System
- o-Fluorophenol (367-12-4)
Safety
- Hazard Codes
- Xn,F,C,Xi,T
- Risk Statements
- 20/21/22-36/37/38-10-63-43-23/24/25-45-40
- Safety Statements
- 28-36/37-36/37/39-26-16-24/25-23-53-36
- RIDADR
- UN 1993 3/PG 3
- WGK Germany
- 3
- RTECS
- SL4530000
- Hazard Note
- Flammable/Corrosive
- TSCA
- T
- HazardClass
- 3
- PackingGroup
- III
- HS Code
- 29081000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F12804
- Product name
- 2-Fluorophenol
- Purity
- 98%
- Packaging
- 10g
- Price
- $45.9
- Updated
- 2024/03/01
- Product number
- F0150
- Product name
- 2-Fluorophenol
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $18
- Updated
- 2024/03/01
- Product number
- F0150
- Product name
- 2-Fluorophenol
- Purity
- >98.0%(GC)
- Packaging
- 250g
- Price
- $101
- Updated
- 2024/03/01
- Product number
- A14979
- Product name
- 2-Fluorophenol, 98%
- Packaging
- 25g
- Price
- $54.65
- Updated
- 2024/03/01
- Product number
- A14979
- Product name
- 2-Fluorophenol, 98%
- Packaging
- 100g
- Price
- $154.65
- Updated
- 2024/03/01
2-Fluorophenol Chemical Properties,Usage,Production
Chemical Properties
Clear colourless to yellow liquid
Uses
2-Fluorophenol is a competitive inhibitor in the oxidation of 3,4-dihydroxyphenylalanine (L-DOPA), a catecholamine precursor that is used as a therapeutic agent for patients with ParkinsonтАЩs disease. 2-Fluorophenol is also used as a sole carbon energy source for bacteria.
Synthesis Reference(s)
Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
Journal of the American Chemical Society, 103, p. 1964, 1981 DOI: 10.1021/ja00398a015
General Description
Liquid or crystalline solid melting at 14-16°C. Corrosive. Density 1.246 g / cm3.
Air & Water Reactions
Highly flammable.
Reactivity Profile
2-Fluorophenol reacts as a weak organic acid. May be incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction with bases. Such heating may initiate polymerization of the organic compound. Sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Nitrated very rapidly, even by dilute nitric acid.
Health Hazard
ACUTE/CHRONIC HAZARDS: Toxic and irritant.
Purification Methods
Pass o-fluorophenol at least twice through a gas chromatographic column for small quantities; otherwise fractionally distil it under reduced pressure. [Beilstein 6 I 97, 6 IV 770.]
2-Fluorophenol Preparation Products And Raw materials
Raw materials
Preparation Products
2-Fluorophenol Suppliers
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View Lastest Price from 2-Fluorophenol manufacturers
- Product
- 2-Fluorophenol 367-12-4
- Price
- US $0.00/KG
- Min. Order
- 25KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-08
- Product
- 2-Fluorophenol 367-12-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-04
- Product
- 2-Fluorophenol 367-12-4
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.99%
- Supply Ability
- 2000 tons
- Release date
- 2024-04-10