ChemicalBook > CAS DataBase List > 2-Fluorophenol

2-Fluorophenol

Product Name
2-Fluorophenol
CAS No.
367-12-4
Chemical Name
2-Fluorophenol
Synonyms
1-Bromo-3-fluorobezene;O-FLUOROPHENOL;uorophenoL;2-Florophenol;2-Flurophenol;2-fluoro-pheno;2-FLUOROPHENOL;o-fluoro-pheno;2-Fluorophenole;2-Fluorophenol f
CBNumber
CB0495831
Molecular Formula
C6H5FO
Formula Weight
112.1
MOL File
367-12-4.mol
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2-Fluorophenol Property

Melting point:
16.1 °C (lit.)
Boiling point:
171-172 °C/741 mmHg (lit.)
Density 
1.256 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.511(lit.)
Flash point:
116 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
37.7g/l
form 
Liquid
pka
8.73(at 25℃)
Specific Gravity
1.256
color 
Clear colorless to light yellow-brownish
Water Solubility 
80.72g/L(25 ºC)
BRN 
1905112
Stability:
Stable. Flammable. Incompatible with strong oxidizing agents.
InChIKey
HFHFGHLXUCOHLN-UHFFFAOYSA-N
CAS DataBase Reference
367-12-4(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 2-fluoro-(367-12-4)
EPA Substance Registry System
o-Fluorophenol (367-12-4)
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Safety

Hazard Codes 
Xn,F,C,Xi,T
Risk Statements 
20/21/22-36/37/38-10-63-43-23/24/25-45-40
Safety Statements 
28-36/37-36/37/39-26-16-24/25-23-53-36
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
RTECS 
SL4530000
Hazard Note 
Flammable/Corrosive
TSCA 
T
HazardClass 
3
PackingGroup 
III
HS Code 
29081000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F12804
Product name
2-Fluorophenol
Purity
98%
Packaging
10g
Price
$45.9
Updated
2024/03/01
TCI Chemical
Product number
F0150
Product name
2-Fluorophenol
Purity
>98.0%(GC)
Packaging
25g
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
F0150
Product name
2-Fluorophenol
Purity
>98.0%(GC)
Packaging
250g
Price
$101
Updated
2024/03/01
Alfa Aesar
Product number
A14979
Product name
2-Fluorophenol, 98%
Packaging
25g
Price
$54.65
Updated
2024/03/01
Alfa Aesar
Product number
A14979
Product name
2-Fluorophenol, 98%
Packaging
100g
Price
$154.65
Updated
2024/03/01
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2-Fluorophenol Chemical Properties,Usage,Production

Chemical Properties

Clear colourless to yellow liquid

Uses

2-Fluorophenol is a competitive inhibitor in the oxidation of 3,4-dihydroxyphenylalanine (L-DOPA), a catecholamine precursor that is used as a therapeutic agent for patients with ParkinsonтАЩs disease. 2-Fluorophenol is also used as a sole carbon energy source for bacteria.

Synthesis Reference(s)

Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
Journal of the American Chemical Society, 103, p. 1964, 1981 DOI: 10.1021/ja00398a015

General Description

Liquid or crystalline solid melting at 14-16°C. Corrosive. Density 1.246 g / cm3.

Air & Water Reactions

Highly flammable.

Reactivity Profile

2-Fluorophenol reacts as a weak organic acid. May be incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction with bases. Such heating may initiate polymerization of the organic compound. Sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Nitrated very rapidly, even by dilute nitric acid.

Health Hazard

ACUTE/CHRONIC HAZARDS: Toxic and irritant.

Purification Methods

Pass o-fluorophenol at least twice through a gas chromatographic column for small quantities; otherwise fractionally distil it under reduced pressure. [Beilstein 6 I 97, 6 IV 770.]

2-Fluorophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Fluorophenol Suppliers

Huai'an Chenhui Technology Co., Ltd.
Tel
13056011912
Email
jianshen1977@126.com
Country
China
ProdList
25
Advantage
58
Weifang Weimeng Chemical Co., Ltd.
Tel
0536-8790166 15105445095
Email
weimengchem@163.com
Country
China
ProdList
471
Advantage
58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
133-96369453 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
862
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
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View Lastest Price from 2-Fluorophenol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Fluorophenol 367-12-4
Price
US $0.00/KG
Min. Order
25KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-08
Hebei Weibang Biotechnology Co., Ltd
Product
2-Fluorophenol 367-12-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04
airuikechemical co., ltd.
Product
2-Fluorophenol 367-12-4
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.99%
Supply Ability
2000 tons
Release date
2024-04-10

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