2-Fluorophenol

Product Name: 2-Fluorophenol
CAS No.: 367-12-4
Chemical Name: 2-Fluorophenol
Synonyms: 1-Bromo-3-fluorobezene;O-FLUOROPHENOL;uorophenoL;2-Florophenol;2-Flurophenol;2-fluoro-pheno;2-FLUOROPHENOL;o-fluoro-pheno;2-Fluorophenole;2-Fluorophenol f
CBNumber: CB0495831
Molecular Formula: C6H5FO
Formula Weight: 112.1
MOL File: 367-12-4.mol

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2-Fluorophenol Property

Melting point:: 16.1 °C (lit.)
Boiling point:: 171-172 °C/741 mmHg (lit.)
Density: 1.256 g/mL at 25 °C (lit.)
refractive index: n20/D 1.511(lit.)
Flash point:: 116 °F
storage temp.: Inert atmosphere,Room Temperature
solubility: 37.7g/l
form: Liquid
pka: 8.73(at 25℃)
Specific Gravity: 1.256
color: Clear colorless to light yellow-brownish
Water Solubility: 80.72g/L(25 ºC)
BRN: 1905112
Stability:: Stable. Flammable. Incompatible with strong oxidizing agents.
InChIKey: HFHFGHLXUCOHLN-UHFFFAOYSA-N
CAS DataBase Reference: 367-12-4(CAS DataBase Reference)
NIST Chemistry Reference: Phenol, 2-fluoro-(367-12-4)
EPA Substance Registry System: o-Fluorophenol (367-12-4)

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Safety

Hazard Codes: Xn,F,C,Xi,T
Risk Statements: 20/21/22-36/37/38-10-63-43-23/24/25-45-40
Safety Statements: 28-36/37-36/37/39-26-16-24/25-23-53-36
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
RTECS: SL4530000
Hazard Note: Flammable/Corrosive
TSCA: T
HazardClass: 3
PackingGroup: III
HS Code: 29081000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: F12804
Product name: 2-Fluorophenol
Purity: 98%
Packaging: 10g
Price: $45.9
Updated: 2024/03/01

TCI Chemical

Product number: F0150
Product name: 2-Fluorophenol
Purity: >98.0%(GC)
Packaging: 25g
Price: $18
Updated: 2024/03/01

TCI Chemical

Product number: F0150
Product name: 2-Fluorophenol
Purity: >98.0%(GC)
Packaging: 250g
Price: $101
Updated: 2024/03/01

Alfa Aesar

Product number: A14979
Product name: 2-Fluorophenol, 98%
Packaging: 25g
Price: $54.65
Updated: 2024/03/01

Alfa Aesar

Product number: A14979
Product name: 2-Fluorophenol, 98%
Packaging: 100g
Price: $154.65
Updated: 2024/03/01

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2-Fluorophenol Chemical Properties,Usage,Production

Chemical Properties

Clear colourless to yellow liquid

Uses

2-Fluorophenol is a competitive inhibitor in the oxidation of 3,4-dihydroxyphenylalanine (L-DOPA), a catecholamine precursor that is used as a therapeutic agent for patients with ParkinsonтАЩs disease. 2-Fluorophenol is also used as a sole carbon energy source for bacteria.

Synthesis Reference(s)

Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
Journal of the American Chemical Society, 103, p. 1964, 1981 DOI: 10.1021/ja00398a015

General Description

Liquid or crystalline solid melting at 14-16°C. Corrosive. Density 1.246 g / cm3.

Air & Water Reactions

Highly flammable.

Reactivity Profile

2-Fluorophenol reacts as a weak organic acid. May be incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction with bases. Such heating may initiate polymerization of the organic compound. Sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Nitrated very rapidly, even by dilute nitric acid.

Health Hazard

ACUTE/CHRONIC HAZARDS: Toxic and irritant.

Purification Methods

Pass o-fluorophenol at least twice through a gas chromatographic column for small quantities; otherwise fractionally distil it under reduced pressure. [Beilstein 6 I 97, 6 IV 770.]

2-Fluorophenol Preparation Products And Raw materials

Raw materials

2-Nitrochlorobenzene Potassium fluoride Hydrogen

Preparation Products

3-Fluoro-4-hydroxybenzaldehyde

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2-Fluorophenol Suppliers

Americas 1 Belgium 3 Canada 4 China 364 Europe 3 France 1 Germany 6 India 23 Indonesia 1 Italy 1 Japan 6 Jordan 1 Norway 1 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 2 United Kingdom 23 United States 53 Global 498

Huai'an Chenhui Technology Co., Ltd.

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J & K SCIENTIFIC LTD.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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Alfa Aesar

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TCI (Shanghai) Development Co., Ltd.

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ShangHai DEMO Chemical Co.,Ltd

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Beijing HwrkChemical Technology Co., Ltd

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Fax: 010-89508210
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Country: China
ProdList: 8418
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View Lastest Price from 2-Fluorophenol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-Fluorophenol 367-12-4
Price: US $0.00/KG
Min. Order: 25KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-08

Hebei Weibang Biotechnology Co., Ltd

Product: 2-Fluorophenol 367-12-4
Price: US $10.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-12-02

Hebei Weibang Biotechnology Co., Ltd

Product: 2-Fluorophenol 367-12-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-04

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367-12-4

367-41-5

FA - FL

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