ChemicalBook > CAS DataBase List > 4-Fluorophenol

4-Fluorophenol

Product Name
4-Fluorophenol
CAS No.
371-41-5
Chemical Name
4-Fluorophenol
Synonyms
Fluorophenol;P-FLUOROPHENOL;FPO;p-Fluorphenol;p-Fluorohenol;4-Fluorphenol;4-FLUOROPHENOL;P-flrorophenol;4-fluoro-pheno;p-fluoro-pheno
CBNumber
CB9672628
Molecular Formula
C6H5FO
Formula Weight
112.1
MOL File
371-41-5.mol
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4-Fluorophenol Property

Melting point:
43-46 °C (lit.)
Boiling point:
185 °C (lit.)
Density 
1.22
Flash point:
155 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
80g/l
form 
Crystalline Solid
pka
9.89(at 25℃)
color 
Yellow-beige to pink
PH
5.4 (H2O, 20℃)(saturated aqueous solution)
Water Solubility 
50 g/L
BRN 
1362752
Stability:
Stable. Flammable. Incompatible with strong oxidizing agents.
Dissociation constant
0 at 27℃
CAS DataBase Reference
371-41-5(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 4-fluoro-(371-41-5)
EPA Substance Registry System
Phenol, 4-fluoro- (371-41-5)
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Safety

Hazard Codes 
Xn,C,T,F+
Risk Statements 
20/21/22-36/37/38-52/53
Safety Statements 
26-37/39-61-36
RIDADR 
UN 2928 6.1/PG 2
WGK Germany 
1
RTECS 
SL4550000
10-23
Hazard Note 
Corrosive/Harmful
TSCA 
T
HazardClass 
6.1
PackingGroup 
III
HS Code 
29081000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F13207
Product name
4-Fluorophenol
Purity
99%
Packaging
25g
Price
$45.7
Updated
2024/03/01
Sigma-Aldrich
Product number
F13207
Product name
4-Fluorophenol
Purity
99%
Packaging
100g
Price
$103
Updated
2024/03/01
TCI Chemical
Product number
F0160
Product name
4-Fluorophenol
Purity
>99.0%(GC)
Packaging
25g
Price
$31
Updated
2024/03/01
TCI Chemical
Product number
F0160
Product name
4-Fluorophenol
Purity
>99.0%(GC)
Packaging
500g
Price
$305
Updated
2024/03/01
Alfa Aesar
Product number
A11945
Product name
4-Fluorophenol, 99%
Packaging
25g
Price
$40.4
Updated
2024/03/01
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4-Fluorophenol Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

4-Fluorophenol is a fluorinated phenolic compound with various applications as a starting reagent for synthesizing pharmaceuticals. It is a widely used intermediate in the industrial production of several drugs, including cisapride and Sabeluzole by Janssen, Sorbinil by Pfizer, and Progabide by Synthelabo.

Definition

ChEBI: 4-fluorophenol is a fluorophenol that is phenol in which the hydrogen para- to the hydroxy group has been replaced by a fluorine. It is a fluorophenol and a member of monofluorobenzenes. It is used as an intermediate in the production of liquid crystals.

Preparation

Acetyl hypofluorite also will fluoro-demetallate benzene derivatives, for example mercury derivatives of phenol gave 4-fluorophenol.

Synthesis Reference(s)

Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8

Hazard

Irritant.

4-Fluorophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Fluorophenol Suppliers

Shanghai Sphchem Co., Ltd.
Tel
21-21-56491756 13512199871
Fax
021-5649-1756
Email
sales@panhongchem.com
Country
China
ProdList
3999
Advantage
55
Wuhan Hongde Yuexin Pharmatech Co.,Ltd
Tel
027-83855393 15071227934
Fax
027-83855393
Email
3306264753@qq.com
Country
China
ProdList
3036
Advantage
58
Neostar United (Changzhou) Industrial Co., Ltd.
Tel
0519-85556579 13376258932
Fax
0519-85557389
Email
project@neostarunited.com
Country
China
ProdList
169
Advantage
58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
133-96369453 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
854
Advantage
58
CE Pharm Co.,Ltd
Tel
15317222985
Fax
binbin.lin@cepharm.cn
Email
bingna.wang@cepharm.cn
Country
China
ProdList
139
Advantage
58
jinkui(taizhou)technology co ltd
Tel
18969655221
Email
530532315@qq.com
Country
China
ProdList
206
Advantage
58
Shanghai Qianlai Pharmaceutical Technology Co., Ltd.
Tel
021-57216911 17740831186
Email
482109853@qq.com
Country
China
ProdList
462
Advantage
58
Nanjing Sincerity Chemical Co. Ltd.
Tel
025-57621892 13245250309
Email
hp@njsincerity.com
Country
China
ProdList
295
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
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View Lastest Price from 4-Fluorophenol manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Fluorophenol 371-41-5
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-21
Henan Fengda Chemical Co., Ltd
Product
4-Fluorophenol 371-41-5
Price
US $9.00-0.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-23
Henan Fengda Chemical Co., Ltd
Product
4-Fluorophenol 371-40-5
Price
US $9.00-0.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-23

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