2,6-Difluoroaniline

Product Name: 2,6-Difluoroaniline
CAS No.: 5509-65-9
Chemical Name: 2,6-Difluoroaniline
Synonyms: 2,6-Difuluoroaniline;2,6-DIFLUOROBENZENAMINE;26DFA;NSC 127234;JACS-5509-65-9;6-Difluoroaniline;Abesili Impurity 8;2,6-DIFLUOROANILINE;2,6- twofluoro aniline;2,6-Difluoroaniline>
CBNumber: CB5478710
Molecular Formula: C6H5F2N
Formula Weight: 129.11
MOL File: 5509-65-9.mol

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2,6-Difluoroaniline Property

Boiling point:: 51-52 °C/15 mmHg (lit.)
Density: 1.199 g/mL at 25 °C (lit.)
refractive index: n20/D 1.508(lit.)
Flash point:: 110 °F
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: Chloroform, Ethyl Acetate (Slightly)
form: Liquid
pka: 1.81±0.10(Predicted)
Specific Gravity: 1.28
color: Clear yellow to brown
Water Solubility: Slightly soluble in water.
BRN: 2802697
Stability:: Hygroscopic
InChI: 1S/C6H5F2N/c7-4-2-1-3-5(8)6(4)9/h1-3H,9H2
InChIKey: ODUZJBKKYBQIBX-UHFFFAOYSA-N
SMILES: Nc1c(F)cccc1F
CAS DataBase Reference: 5509-65-9(CAS DataBase Reference)
NIST Chemistry Reference: 2,6-Difluoroaniline(5509-65-9)
EPA Substance Registry System: 2,6-Difluoroaniline (5509-65-9)

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Safety

Hazard Codes: Xn,Xi,F
Risk Statements: 10-20/21/22-36/37/38
Safety Statements: 36-36/37/39-26-23-16-16/23/26/36/37/39-24/25
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
F: 8-10-23
Hazard Note: Irritant
TSCA: TSCA listed
HazardClass: 3
PackingGroup: III
HS Code: 29214210
Storage Class: 3 - Flammable liquids
Hazard Classifications: Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Flam. Liq. 3
Skin Sens. 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H317May cause an allergic skin reaction

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 196614
Product name: 2,6-Difluoroaniline
Purity: ≥97%
Packaging: 5g
Price: $56.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: 196614
Product name: 2,6-Difluoroaniline
Purity: ≥97%
Packaging: 25g
Price: $74.3
Updated: 2025/07/31

TCI Chemical

Product number: D1635
Product name: 2,6-Difluoroaniline
Purity: >98.0%(GC)
Packaging: 5g
Price: $26
Updated: 2025/07/31

TCI Chemical

Product number: D1635
Product name: 2,6-Difluoroaniline
Purity: >98.0%(GC)
Packaging: 25g
Price: $77
Updated: 2025/07/31

Sigma-Aldrich

Product number: 196614
Product name: 2,6-Difluoroaniline
Purity: ≥97%
Packaging: 100g
Price: $100.1
Updated: 2025/07/31

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2,6-Difluoroaniline Chemical Properties,Usage,Production

Chemical Properties

clear yellow to brown liquid

Uses

2,6-Difluoroaniline is an important chemical in the sythesis technology for high-efficiency insecticide.

Uses

2,6-Difluoroaniline was used in the synthesis of:

N-2,6-difluorophenyl-5-methoxy-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamide, herbicidal compound
series of 2,6,9-trisubstituted purine inhibitors of p38α kinase
substituted phenylthiomorpholine dioxide, an active pharmaceutical intermediate

Uses

2,6-Difluoroaniline and several related primary amines are oxidized in chloroform by peroxybenzoic acid to the corresponding nitroso compounds. For example, treatment of 2,6-difluoroaniline with sodium azide can obtain 4-fluoro-2,1,3-benzoxadiazole, and the product is nitrified to obtain 7-nitro derivatives[1]. 2,6-Difluoroaniline is an important raw material and intermediate in organic synthesis, medicine, pesticides, dyes and other fields.

Toxics Screening Level

The initial threshold screening level (ITSL) for 2,6-difluoroaniline (DFA) is 2.0 μg/m3 based on an annual averaging time.

References

[1] Nunno L, et al. Oxidation of substituted anilines to nitroso-compounds. J. Chem. Soc. C, 1970; 9: 1433-1434.

2,6-Difluoroaniline Preparation Products And Raw materials

Raw materials

2,6-Difluorobenzamide

Preparation Products

4-(CHLOROSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE DBD-PZ 4-(N,N-DIMETHYLAMINOSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE 4-Bromo-2,6-difluoroaniline 2,6-DIFLUORO-4-NITROANILINE 4-FLUORO-2,1,3-BENZOXADIAZOLE

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2,6-Difluoroaniline Suppliers

Americas 1 Belgium 3 Canada 3 China 455 Europe 4 France 3 Germany 9 India 22 Italy 1 Japan 4 Jordan 1 Slovakia 1 Switzerland 2 The Netherlands 2 Ukraine 2 United Kingdom 22 United States 48 Global 583

Tai 'an Huanyu Chemical Co., LTD

Tel: 13176825516; 13176825516
Email: 78995114@qq.com
Country: China
ProdList: 83
Advantage: 58

Shanghai QianJin Chemical Technology Co., Ltd

Tel: 021-20900665 17321230821
Fax: 021-20900665
Email: 2986274987@qq.com
Country: China
ProdList: 807
Advantage: 55

Weifang QianJin Fine Chemical Co., Ltd.

Tel: 18753684562
Fax: 0536-8897109
Email: 1577399715@qq.COM
Country: China
ProdList: 1739
Advantage: 55

Baoding Bink New Materials Co., Ltd.

Tel: 17531190177
Fax: QQ:672648158
Email: peter@yan-xi.com
Country: China
ProdList: 278
Advantage: 58

Qufu Delu Biotechnology Co., Ltd

Tel: 13562421518
Email: deluxe11@163.com
Country: China
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Hubei deante Chemical Technology Co., Ltd

Tel: 18707110115
Email: 2905723734@qq.com
Country: China
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Shandong Lifan Chemical Co. LTD

Tel: 17864861555
Email: 896889070@qq.com
Country: China
ProdList: 99
Advantage: 58

Zhejiang Xieshi New Materials Co., Ltd.,

Tel: 17858121723
Email: sales09@xieshichem.com
Country: China
ProdList: 190
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Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Email: 2819742715@qq.com
Country: China
ProdList: 3997
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

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View Lastest Price from 2,6-Difluoroaniline manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2,6-Difluoroaniline 5509-65-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 10000KGS
Release date: 2025-06-24

Gansu Jinyuantai New Material Co., Ltd.

Product: 2,6-Difluoroaniline 5509-65-9
Price: US $0.00/KG
Min. Order: 1000KG
Purity: 99
Supply Ability: 20000
Release date: 2025-05-19

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2,6-Difluoroaniline 5509-65-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-08

5509-65-9, 2,6-DifluoroanilineRelated Search:

N,N-Dimethylaniline 2-Fluoroaniline Diphenylamine 2,4,5-Trifluoroaniline 4-(Trifluoromethoxy)aniline 3,5-Difluoroaniline N,N-Dimethyl-1,4-phenylenediamine Sodium diphenylamine-4-sulfonate 4-Fluoroaniline 2,6-Difluorobenzylamine 2,3,6-TRIFLUOROANILINE 3,4-Difluoroaniline 2,3,4,6-TETRAFLUORONITROBENZENE 2,6-DIFLUOROPHENYL ISOCYANATE 4-AMINO-2,3,5,6-TETRAFLUOROBENZOIC ACID 4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE PENTAFLUORONITROBENZENE 2,4,6-Trifluoroaniline

Benzenamine, 2,6-difluoro-

2,6-DIFLUOROANILINE

2,6-DIFLUOROBENZENAMINE

2,6-DIFLUOROANILINE, 97+%

2,6-Difluoroaniline,98%

2,6-Difluoroaniline,min.97%

2,6-Difluoroaniline 98%

2,6-Difluoroaniline, min. 97%

2,6-Difuluoroaniline

2,6-Difuluorobenzenamine

2,6-DifluorobenzeneaMine

2,6-DifluorophenylaMine

NSC 127234

6-Difluoroaniline

2-Amino-1,3-difluorobenzene

2,6-Difluoroaniline, 97% 5ML

JACS-5509-65-9

2,6- twofluoro aniline

2,6-Difluoroaniline 98%, 6-Difluoroaniline 98%

2,6-Difluoroaniline 98% Min.

2,6-Difluoroaniline&gt

2,6-Difluoroaniline ISO 9001：2015 REACH

Abemaciclib Impurity 9

Vandetanib Impurity 13

Abesili Impurity 8

2,6-Difluoroaniline, 96%

26DFA

5509-65-9

F2C6H3NH2

C6F2H5N1

C2 to C6

Amines

Building Blocks

Organic Building Blocks

Nitrogen Compounds

Anilines, Aromatic Amines and Nitro Compounds

Fluorobenzene

Miscellaneous

Fluorobenzene Series

Amines

C2 to C6

Nitrogen Compounds

bc0001