ChemicalBook > CAS DataBase List > 2,6-Difluoroaniline

2,6-Difluoroaniline

Product Name
2,6-Difluoroaniline
CAS No.
5509-65-9
Chemical Name
2,6-Difluoroaniline
Synonyms
2,6-Difuluoroaniline;2,6-DIFLUOROBENZENAMINE;NSC 127234;JACS-5509-65-9;6-Difluoroaniline;2,6-DIFLUOROANILINE;2,6- twofluoro aniline;2,6-Difluoroaniline>Abemaciclib Impurity 9;Vandetanib Impurity 13
CBNumber
CB5478710
Molecular Formula
C6H5F2N
Formula Weight
129.11
MOL File
5509-65-9.mol
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2,6-Difluoroaniline Property

Boiling point:
51-52 °C/15 mmHg (lit.)
Density 
1.199 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.508(lit.)
Flash point:
110 °F
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Chloroform, Ethyl Acetate (Slightly)
form 
Liquid
pka
1.81±0.10(Predicted)
color 
Clear yellow to brown
Specific Gravity
1.28
Water Solubility 
Slightly soluble in water.
BRN 
2802697
Stability:
Hygroscopic
InChIKey
ODUZJBKKYBQIBX-UHFFFAOYSA-N
CAS DataBase Reference
5509-65-9(CAS DataBase Reference)
NIST Chemistry Reference
2,6-Difluoroaniline(5509-65-9)
EPA Substance Registry System
2,6-Difluoroaniline (5509-65-9)
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Safety

Hazard Codes 
Xn,Xi,F
Risk Statements 
10-20/21/22-36/37/38
Safety Statements 
36-36/37/39-26-23-16-16/23/26/36/37/39-24/25
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
F 
8-10-23
Hazard Note 
Irritant
HazardClass 
3
PackingGroup 
III
HS Code 
29214210
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H317May cause an allergic skin reaction

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
196614
Product name
2,6-Difluoroaniline
Purity
≥97%
Packaging
5g
Price
$54.4
Updated
2024/03/01
Sigma-Aldrich
Product number
196614
Product name
2,6-Difluoroaniline
Purity
≥97%
Packaging
25g
Price
$72.1
Updated
2024/03/01
TCI Chemical
Product number
D1635
Product name
2,6-Difluoroaniline
Purity
>98.0%(GC)
Packaging
5g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
D1635
Product name
2,6-Difluoroaniline
Purity
>98.0%(GC)
Packaging
25g
Price
$77
Updated
2024/03/01
Alfa Aesar
Product number
A13020
Product name
2,6-Difluoroaniline, 98%
Packaging
5g
Price
$37.65
Updated
2024/03/01
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2,6-Difluoroaniline Chemical Properties,Usage,Production

Chemical Properties

clear yellow to brown liquid

Uses

2,6-Difluoroaniline is an important chemical in the sythesis technology for high-efficiency insecticide.

Uses

2,6-Difluoroaniline was used in the synthesis of:

  • N-2,6-difluorophenyl-5-methoxy-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamide, herbicidal compound
  • series of 2,6,9-trisubstituted purine inhibitors of p38α kinase
  • substituted phenylthiomorpholine dioxide, an active pharmaceutical intermediate

Uses

2,6-Difluoroaniline and several related primary amines are oxidized in chloroform by peroxybenzoic acid to the corresponding nitroso compounds. For example, treatment of 2,6-difluoroaniline with sodium azide can obtain 4-fluoro-2,1,3-benzoxadiazole, and the product is nitrified to obtain 7-nitro derivatives[1]. 2,6-Difluoroaniline is an important raw material and intermediate in organic synthesis, medicine, pesticides, dyes and other fields.

References

[1] Nunno L, et al. Oxidation of substituted anilines to nitroso-compounds. J. Chem. Soc. C, 1970; 9: 1433-1434.

2,6-Difluoroaniline Preparation Products And Raw materials

Raw materials

2,6-Difluorobenzamide

Preparation Products

4-(CHLOROSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE DBD-PZ 4-(N,N-DIMETHYLAMINOSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE 4-Bromo-2,6-difluoroaniline 2,6-DIFLUORO-4-NITROANILINE 4-FLUORO-2,1,3-BENZOXADIAZOLE
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2,6-Difluoroaniline Suppliers

Americas 1 Belgium 3 Canada 3 China 439 Europe 4 France 3 Germany 9 India 22 Italy 1 Japan 4 Jordan 1 Slovakia 1 Switzerland 2 The Netherlands 2 Ukraine 2 United Kingdom 22 United States 48 Global 567
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View Lastest Price from 2,6-Difluoroaniline manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2,6-Difluoroaniline 5509-65-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-08
Hebei Chuanghai Biotechnology Co,.LTD
Product
2,6-Difluoroaniline 5509-65-9
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-14
Henan Fengda Chemical Co., Ltd
Product
2,6-Difluoroaniline 5509-65-9
Price
US $10.00-3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-26

5509-65-9, 2,6-DifluoroanilineRelated Search:

N,N-Dimethylaniline 2-Fluoroaniline Diphenylamine 2,4,5-Trifluoroaniline 4-(Trifluoromethoxy)aniline 3,5-Difluoroaniline N,N-Dimethyl-1,4-phenylenediamine Sodium diphenylamine-4-sulfonate 4-Fluoroaniline 2,6-Difluorobenzylamine 2,3,6-TRIFLUOROANILINE 3,4-Difluoroaniline 2,3,4,6-TETRAFLUORONITROBENZENE 2,6-DIFLUOROPHENYL ISOCYANATE 4-AMINO-2,3,5,6-TETRAFLUOROBENZOIC ACID 4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE PENTAFLUORONITROBENZENE 2,4,6-Trifluoroaniline

  • Benzenamine, 2,6-difluoro-
  • 2,6-DIFLUOROANILINE
  • 2,6-DIFLUOROBENZENAMINE
  • 2,6-DIFLUOROANILINE, 97+%
  • 2,6-Difluoroaniline,98%
  • 2,6-Difluoroaniline,min.97%
  • 2,6-Difluoroaniline 98%
  • 2,6-Difluoroaniline, min. 97%
  • 2,6-Difuluoroaniline
  • 2,6-Difuluorobenzenamine
  • 2,6-DifluorobenzeneaMine
  • 2,6-DifluorophenylaMine
  • NSC 127234
  • 6-Difluoroaniline
  • 2-Amino-1,3-difluorobenzene
  • 2,6-Difluoroaniline, 97% 5ML
  • JACS-5509-65-9
  • 2,6- twofluoro aniline
  • 2,6-Difluoroaniline 98%, 6-Difluoroaniline 98%
  • 2,6-Difluoroaniline 98% Min.
  • 2,6-Difluoroaniline&gt
  • 2,6-Difluoroaniline ISO 9001：2015 REACH
  • Abemaciclib Impurity 9
  • Vandetanib Impurity 13
  • 5509-65-9
  • F2C6H3NH2
  • C6F2H5N1
  • C2 to C6
  • Amines
  • Building Blocks
  • Organic Building Blocks
  • Nitrogen Compounds
  • Anilines, Aromatic Amines and Nitro Compounds
  • Fluorobenzene
  • Miscellaneous
  • Fluorobenzene Series
  • Amines
  • C2 to C6
  • Nitrogen Compounds
  • bc0001