3,5-Difluoroaniline
Synthesis- Product Name
- 3,5-Difluoroaniline
- CAS No.
- 372-39-4
- Chemical Name
- 3,5-Difluoroaniline
- Synonyms
- 3,5-DIFLUOROBENZENAMINE;NSC 81289;5-Difluoroaniline;3,5-Difluoranilin;3,5-DIFLUOROANILINE;3, 5-2 fluoro aniline;3,5-Difluoroaniline>3,5-Difluoroaniline,98%;3,5-Difluorophenylamine;3,5-Difluoroaniline 98%
- CBNumber
- CB2339018
- Molecular Formula
- C6H5F2N
- Formula Weight
- 129.11
- MOL File
- 372-39-4.mol
3,5-Difluoroaniline Property
- Melting point:
- 37-41 °C (lit.)
- Boiling point:
- 80°C 20mm
- Density
- 1,295 g/cm3
- refractive index
- 1,512-1,514
- Flash point:
- 167 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Water Solubility
- Insoluble in water
- form
- Low Melting Solid
- pka
- 2.57±0.10(Predicted)
- color
- White to yellow
- BRN
- 2802286
- InChI
- InChI=1S/C6H5F2N/c7-4-1-5(8)3-6(9)2-4/h1-3H,9H2
- InChIKey
- KQOIBXZRCYFZSO-UHFFFAOYSA-N
- SMILES
- C1(N)=CC(F)=CC(F)=C1
- CAS DataBase Reference
- 372-39-4(CAS DataBase Reference)
- EPA Substance Registry System
- 3,5-Difluoroaniline (372-39-4)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 28-36/37/39-26-36
- RIDADR
- UN 1325 4.1/PG 2
- WGK Germany
- 3
- F
- 8-10-23
- Hazard Note
- Irritant
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29214200
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D2665
- Product name
- 3,5-Difluoroaniline
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $40
- Updated
- 2025/07/31
- Product number
- D2665
- Product name
- 3,5-Difluoroaniline
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $196
- Updated
- 2025/07/31
- Product number
- D442325
- Product name
- 3,5-Difluoroaniline
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- E872
- Product name
- 3,5-Difluoroaniline
- Packaging
- 5g
- Price
- $16
- Updated
- 2021/12/16
- Product number
- JK410839
- Product name
- 3,5-Difluoroaniline
- Purity
- 98%
- Packaging
- 1g
- Price
- $19
- Updated
- 2021/12/16
3,5-Difluoroaniline Chemical Properties,Usage,Production
Synthesis
Work on halogenated benzenes has also demonstrated the versatility of this technique and a variety of fluoro-chloro and -bromo benzenes may be de-brominated and de-chlorinated. Two patents describe removal of chlorine from 2,6-dichloro-3,5- difluoronitrobenzene giving 3,5-difluoroaniline.
Chemical Properties
white to yellowish low melting solid
Uses
3,5-Difluoroaniline has been used in the preparation of 3,5-difluorodimethylaniline.
General Description
In vitro nephrotoxic effects of 3,5-difluoroaniline has been investigated in renal cortical slices obtained from the kidneys of untreated, male Fischer 344 rats.
References
[1] Patent: CN108314624, 2018, A. Location in patent: Paragraph 0054; 0055; 0056; 0057
3,5-Difluoroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,5-Difluoroaniline manufacturers
- Product
- 3,5-Difluoroaniline 372-39-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-31
- Product
- 3,5-Difluoroaniline 372-39-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-09-13
- Product
- 3,5-Difluoroaniline 372-39-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-02-27