Synthesis
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3,5-Difluoroaniline

Synthesis
Product Name
3,5-Difluoroaniline
CAS No.
372-39-4
Chemical Name
3,5-Difluoroaniline
Synonyms
3,5-DIFLUOROBENZENAMINE;NSC 81289;5-Difluoroaniline;3,5-Difluoranilin;3,5-DIFLUOROANILINE;3, 5-2 fluoro aniline;3,5-Difluoroaniline>3,5-Difluoroaniline,98%;3,5-Difluorophenylamine;3,5-Difluoroaniline 98%
CBNumber
CB2339018
Molecular Formula
C6H5F2N
Formula Weight
129.11
MOL File
372-39-4.mol
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3,5-Difluoroaniline Property

Melting point:
37-41 °C (lit.)
Boiling point:
80°C 20mm
Density 
1,295 g/cm3
refractive index 
1,512-1,514
Flash point:
167 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
Water Solubility 
Insoluble in water
form 
Low Melting Solid
pka
2.57±0.10(Predicted)
color 
White to yellow
BRN 
2802286
CAS DataBase Reference
372-39-4(CAS DataBase Reference)
EPA Substance Registry System
3,5-Difluoroaniline (372-39-4)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
28-36/37/39-26-36
RIDADR 
UN 1325 4.1/PG 2
WGK Germany 
3
8-10-23
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D2665
Product name
3,5-Difluoroaniline
Purity
>98.0%(GC)
Packaging
5g
Price
$40
Updated
2024/03/01
TCI Chemical
Product number
D2665
Product name
3,5-Difluoroaniline
Purity
>98.0%(GC)
Packaging
25g
Price
$196
Updated
2024/03/01
Alfa Aesar
Product number
A16528
Product name
3,5-Difluoroaniline, 98+%
Packaging
5g
Price
$73.65
Updated
2024/03/01
Alfa Aesar
Product number
A16528
Product name
3,5-Difluoroaniline, 98+%
Packaging
25g
Price
$253.65
Updated
2024/03/01
Alfa Aesar
Product number
A16528
Product name
3,5-Difluoroaniline, 98+%
Packaging
100g
Price
$905
Updated
2021/12/16
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3,5-Difluoroaniline Chemical Properties,Usage,Production

Synthesis

Work on halogenated benzenes has also demonstrated the versatility of this technique and a variety of fluoro-chloro and -bromo benzenes may be de-brominated and de-chlorinated. Two patents describe removal of chlorine from 2,6-dichloro-3,5- difluoronitrobenzene giving 3,5-difluoroaniline.

Chemical Properties

white to yellowish low melting solid

Uses

3,5-Difluoroaniline has been used in the preparation of 3,5-difluorodimethylaniline.

General Description

In vitro nephrotoxic effects of 3,5-difluoroaniline has been investigated in renal cortical slices obtained from the kidneys of untreated, male Fischer 344 rats.

3,5-Difluoroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-Difluoroaniline Suppliers

Anstar Chemical (Group) Co.,Ltd.
Tel
18053179586
Email
export@anstarchemical.com
Country
China
ProdList
343
Advantage
58
Shanghai Sphchem Co., Ltd.
Tel
21-21-56491756 13512199871
Fax
021-5649-1756
Email
sales@panhongchem.com
Country
China
ProdList
4001
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7508
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
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View Lastest Price from 3,5-Difluoroaniline manufacturers

Henan Fengda Chemical Co., Ltd
Product
3,5-Difluoroaniline 372-39-4
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22
Hebei Duling International Trade Co. LTD
Product
3,5-Difluoroaniline 372-39-4
Price
US $60.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50tons
Release date
2023-02-23
Shaanxi Dideu Medichem Co. Ltd
Product
3,5-Difluoroaniline 372-39-4
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-17

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