Uses
ChemicalBook > CAS DataBase List > 2-AMINO-4,6-DIFLUOROBENZOIC ACID

2-AMINO-4,6-DIFLUOROBENZOIC ACID

Uses
Product Name
2-AMINO-4,6-DIFLUOROBENZOIC ACID
CAS No.
126674-77-9
Chemical Name
2-AMINO-4,6-DIFLUOROBENZOIC ACID
Synonyms
BUTTPARK 49\07-42;2-AMINO-4,6-DIFLUOROBENZOIC ACID;Benzoic acid, 2-aMino-4,6-difluoro-;2-AMino-4,6-difluorobenzoic acid 97%;2-Amino-4,6-difluorobenzoic acid ,97%;2-Amino-4,6-difluorobenzoic acid, 95%;2-AMino-4,6-difluorobenzoic acid, 6-difluorobenzoic acid;2-Carboxy-3,5-difluoroaniline, 4,6-Difluoroanthranilic acid
CBNumber
CB1692264
Molecular Formula
C7H5F2NO2
Formula Weight
173.12
MOL File
126674-77-9.mol
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2-AMINO-4,6-DIFLUOROBENZOIC ACID Property

Boiling point:
305.8±42.0 °C(Predicted)
Density 
1.536
storage temp. 
RT, protect from light
form 
wooly crystalline powder
pka
3.95±0.10(Predicted)
color 
Light yellow/gold
Sensitive 
Air Sensitive
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Safety

Hazard Codes 
Xi
HS Code 
2916310000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Apolloscientific
Product number
PC4086
Product name
2-Amino-4,6-difluorobenzoicacid
Packaging
250mg
Price
$25
Updated
2021/12/16
SynQuest Laboratories
Product number
4657-3-17
Product name
2-Amino-4,6-difluorobenzoic acid
Packaging
250mg
Price
$28
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54385
Product name
2-Amino-4,6-difluorobenzoic acid
Packaging
250mg
Price
$85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54385
Product name
2-Amino-4,6-difluorobenzoic acid
Packaging
500mg
Price
$135
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54385
Product name
2-Amino-4,6-difluorobenzoic acid
Packaging
1g
Price
$362.6
Updated
2021/12/16
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2-AMINO-4,6-DIFLUOROBENZOIC ACID Chemical Properties,Usage,Production

Uses

2-Amino-4,6-difluorobenzoic acid is an important pharmaceutical and pesticide intermediate, and it can also be used in liquid crystal materials. It has the advantages of high value and good market prospects.

Synthesis

126674-93-9

126674-77-9

Stage 3: Synthesis of 2-amino-4,6-difluorobenzoic acid A solution of sodium hydroxide (6.70 g, 167 mmol) and 30% hydrogen peroxide (6.7 mL) in water (60 mL) was added dropwise to a suspension of the stage 2 product (4.58 g, 25 mmol) in water (125 mL) and the reaction was carried out at 0 °C. Subsequently, the reaction mixture was stirred at room temperature for 20 hours. Upon completion of the reaction, the pH was adjusted to 3 with formic acid (~11 mL, taking care to control the rate of addition to prevent violent foaming), at which point the target compound began to precipitate. The precipitate was collected by filtration and dried in a desiccator using phosphorus pentoxide to give 3.72 g of white solid product (86% yield). The melting point of the product was 198-202 °C.

References

[1] Patent: US2008/293749, 2008, A1. Location in patent: Page/Page column 14
[2] Journal of Medicinal Chemistry, 2006, vol. 49, # 22, p. 6465 - 6488
[3] Organic Process Research and Development, 2010, vol. 14, # 5, p. 1078 - 1087

2-AMINO-4,6-DIFLUOROBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-4,6-DIFLUOROBENZOIC ACID Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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Capot Chemical Co., Ltd
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Shanghai Ennopharm Co., Ltd.
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View Lastest Price from 2-AMINO-4,6-DIFLUOROBENZOIC ACID manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Amino-4,6-difluorobenzoic acid 126674-77-9
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-07
LY Global chemicals co.,ltd .
Product
2-AMINO-4,6-DIFLUOROBENZOIC ACID 126674-77-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98.0%
Supply Ability
1000kg
Release date
2023-04-05
Career Henan Chemical Co
Product
2-Amino-4,6-difluorobenzoic acid 126674-77-9
Price
US $1.00/KG
Min. Order
1g
Purity
98%
Supply Ability
200kgs
Release date
2020-01-09