Synthesis
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3,5-Difluoroaniline

Synthesis
Product Name
3,5-Difluoroaniline
CAS No.
372-39-4
Chemical Name
3,5-Difluoroaniline
Synonyms
3,5-DIFLUOROBENZENAMINE;NSC 81289;5-Difluoroaniline;3,5-Difluoranilin;3,5-DIFLUOROANILINE;3, 5-2 fluoro aniline;3,5-Difluoroaniline>3,5-Difluoroaniline,98%;3,5-Difluorophenylamine;3,5-Difluoroaniline 98%
CBNumber
CB2339018
Molecular Formula
C6H5F2N
Formula Weight
129.11
MOL File
372-39-4.mol
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3,5-Difluoroaniline Property

Melting point:
37-41 °C (lit.)
Boiling point:
80°C 20mm
Density 
1,295 g/cm3
refractive index 
1,512-1,514
Flash point:
167 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
Water Solubility 
Insoluble in water
form 
Low Melting Solid
pka
2.57±0.10(Predicted)
color 
White to yellow
BRN 
2802286
CAS DataBase Reference
372-39-4(CAS DataBase Reference)
EPA Substance Registry System
3,5-Difluoroaniline (372-39-4)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
28-36/37/39-26-36
RIDADR 
UN 1325 4.1/PG 2
WGK Germany 
3
F 
8-10-23
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D2665
Product name
3,5-Difluoroaniline
Purity
>98.0%(GC)
Packaging
5g
Price
$40
Updated
2024/03/01
TCI Chemical
Product number
D2665
Product name
3,5-Difluoroaniline
Purity
>98.0%(GC)
Packaging
25g
Price
$196
Updated
2024/03/01
Alfa Aesar
Product number
A16528
Product name
3,5-Difluoroaniline, 98+%
Packaging
5g
Price
$73.65
Updated
2024/03/01
Alfa Aesar
Product number
A16528
Product name
3,5-Difluoroaniline, 98+%
Packaging
25g
Price
$253.65
Updated
2024/03/01
Alfa Aesar
Product number
A16528
Product name
3,5-Difluoroaniline, 98+%
Packaging
100g
Price
$905
Updated
2021/12/16
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3,5-Difluoroaniline Chemical Properties,Usage,Production

Synthesis

Work on halogenated benzenes has also demonstrated the versatility of this technique and a variety of fluoro-chloro and -bromo benzenes may be de-brominated and de-chlorinated. Two patents describe removal of chlorine from 2,6-dichloro-3,5- difluoronitrobenzene giving 3,5-difluoroaniline.

Chemical Properties

white to yellowish low melting solid

Uses

3,5-Difluoroaniline has been used in the preparation of 3,5-difluorodimethylaniline.

General Description

In vitro nephrotoxic effects of 3,5-difluoroaniline has been investigated in renal cortical slices obtained from the kidneys of untreated, male Fischer 344 rats.

3,5-Difluoroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

2-AMINO-4,6-DIFLUOROBENZOIC ACID 4-AMINO-2,6-DIFLUORO-BENZALDEHYDE
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3,5-Difluoroaniline Suppliers

Americas 1 Belgium 4 China 342 Europe 3 France 3 Germany 9 India 17 Indonesia 1 Italy 1 Japan 4 Jordan 1 Slovakia 1 South Africa 1 Switzerland 2 Ukraine 2 United Kingdom 20 United States 46 Global 458
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar, Thermo Fisher Scientific
Tel
--
Fax
--
Email
es@alfa.com
Country
Germany
ProdList
5123
Advantage
58
CHEMOS GmbH & Co. KG
Tel
--
Fax
--
Email
chemos@chemos.de
Country
Germany
ProdList
6727
Advantage
58
Karl H. Boddin Chemiehandel GmbH
Tel
--
Fax
--
Country
Germany
ProdList
1036
Advantage
43
PARAGOS
Tel
--
Fax
--
Email
info@paragos.com
Country
Germany
ProdList
6371
Advantage
39
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
Arry International Group Limited
Tel
--
Fax
--
Email
info@arry-nano.com
Country
Germany
ProdList
136
Advantage
73
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
Hansa Fine Chemicals GmbH
Tel
--
Fax
--
Email
jbarten@hfc-chemicals.com
Country
Germany
ProdList
3132
Advantage
38
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View Lastest Price from 3,5-Difluoroaniline manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
3,5-Difluoroaniline 372-39-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-31
Hebei Yanxi Chemical Co., Ltd.
Product
3,5-Difluoroaniline 372-39-4
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-09-13
Henan Fengda Chemical Co., Ltd
Product
3,5-Difluoroaniline 372-39-4
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22

372-39-4, 3,5-DifluoroanilineRelated Search:

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