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thiosemicarbazide

Product Name
thiosemicarbazide
CAS No.
79-19-6
Chemical Name
thiosemicarbazide
Synonyms
HYDRAZINECARBOTHIOAMIDE;TSC;Aminothiourea;n-aminothiourea;TSZ;3-thiosemicarbazide;CHP3;NSC 2213;ai3-16319;NSC 31792
CBNumber
CB0132714
Molecular Formula
CH5N3S
Formula Weight
91.14
MOL File
79-19-6.mol
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thiosemicarbazide Property

Melting point:
180-183 °C (dec.)(lit.)
Boiling point:
208.6±23.0 °C(Predicted)
Density 
1.221 (estimate)
vapor pressure 
1.15Pa at 25℃
refractive index 
1.5800 (estimate)
storage temp. 
Store at +15°C to +25°C.
solubility 
DMSO : 125 mg/mL (1371.52 mM; Need ultrasonic)
pka
pK1:1.5(+1) (25°C,μ=0.1)
form 
Powder
color 
White to light yellow
PH
5-7 (50g/l, H2O, 20℃)
Water Solubility 
soluble
Merck 
14,9361
BRN 
506320
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
BRWIZMBXBAOCCF-UHFFFAOYSA-N
LogP
-1.67
CAS DataBase Reference
79-19-6(CAS DataBase Reference)
NIST Chemistry Reference
Hydrazinecarbothioamide(79-19-6)
EPA Substance Registry System
Thiosemicarbazide (79-19-6)
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Safety

Hazard Codes 
T+
Risk Statements 
28-52/53-26/27/28
Safety Statements 
22-26-36/37-45-61-28A-36/37/39
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
VT4200000
8-9-23
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29309070
HS Code 
29335995
Hazardous Substances Data
79-19-6(Hazardous Substances Data)
Toxicity
LD50 orally in adult Norway rats: 13 mg/kg, Dieke, Proc. Soc. Exp. Biol. Med. 70, 688 (1949)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
89050
Product name
Thiosemicarbazide
Purity
puriss. p.a., 98%
Packaging
25g
Price
$48.7
Updated
2024/03/01
Sigma-Aldrich
Product number
89050
Product name
Thiosemicarbazide
Purity
puriss. p.a., 98%
Packaging
100g
Price
$65.2
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21119
Product name
Thiosemicarbazide
Purity
for synthesis
Packaging
1kg
Price
$252
Updated
2022/05/15
TCI Chemical
Product number
T0221
Product name
Thiosemicarbazide
Purity
>98.0%(T)
Packaging
25g
Price
$56
Updated
2024/03/01
TCI Chemical
Product number
T0221
Product name
Thiosemicarbazide
Purity
>98.0%(T)
Packaging
100g
Price
$139
Updated
2024/03/01
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thiosemicarbazide Chemical Properties,Usage,Production

Chemical Properties

white crystalline solid

Chemical Properties

Thiosemicarbazide is an odorless, white crystalline powder.

Uses

Used in TLC to stain alpha-keto acidsThiosemicarbazide is used as a reagent for ketones as well as chemical intermediate. It is involved in the detection of metals. It is also used in photography. Further, it is effective for controlling bacterial leaf blight in rice. In addition to this, it is used to prepare 1,3,4-thiadiazoles.

Uses

As a reagent for detection of metals.

Definition

ChEBI: Hydrazinecarbothioamide is a member of the class of thioureas that is thiourea in which a hydrogen of one of the amino groups is replaced by an amino group. It is a member of hydrazines, a thiocarboxamide and a member of thioureas.

General Description

N-Aminothiourea is a white crystalline powder and is odorless. N-Aminothiourea is used as a reagent for ketones and certain metals, for photography and as a rodenticide. N-Aminothiourea is also effective for control of bacterial leaf blight of rice. Not a registered pesticide in the U.S. N-Aminothiourea is a chemical intermediate for herbicides and a reagent for detection of metals.

Reactivity Profile

Isocyanates and thioisocyanates are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].

Health Hazard

N-Aminothiourea is highly toxic by ingestion. May induce goiter and cause delayed toxic effects in blood and skin. May be mutagenic in human cells.

Fire Hazard

When heated to decomposition, very toxic fumes of sulfur oxides and nitrogen oxides are emitted.

Flammability and Explosibility

Non flammable

Safety Profile

Poison by ingestion, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx.

Potential Exposure

Thiosemicarbazide is a dithiocarbamide compound is used as an intermedialte for pharmaceuticals and herbicides; as a reagent for ketones and certain metals; in certain photography and dye operations; as a rodenticide. It is also effective for control of bacterial leaf blight of rice.

Shipping

UN2771 Thiosemicarbazide, pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Purification Methods

Crystallise thiosemicarbazide from H2O (solubility is 20.3% w/w at 80o). The hydrochloride has m 190-191o(dec, 184o also reported). It forms salts with heavy metals. [Beilstein 3 H 195, 3 I 79, 3 II 134, 3 III 315, 3 IV 374.]

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.) and strong reducing agents; contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. May react with nitrates.

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thiosemicarbazide Suppliers

Hubei zhonglong Kangsheng Fine Chemical Co., Ltd
Tel
027-027-83850178 18162590268
Fax
027-83850178
Email
1984393783@qq.com
Country
China
ProdList
3722
Advantage
58
Hubei Hicks Biochemical Co., Ltd
Tel
17362916295; 17362916295
Email
w17362916295@163.com
Country
China
ProdList
4046
Advantage
58
JINAN SHENGQI PHARMACEUTICAL CO., LTD
Tel
0531-0531-88895833 15552594168
Email
2509590879@qq.com
Country
China
ProdList
208
Advantage
58
Huai Hua Binfengchem Co., Ltd
Tel
0745-2866851 17307457092
Email
sales@bingfengchem.com
Country
China
ProdList
361
Advantage
58
Jinan Shengqi Pharmaceutical Co., Ltd
Tel
0531-88892685 18660160628
Email
2153390475@qq.com
Country
China
ProdList
198
Advantage
58
Fuxin Kaituo Fine Chemical Technology Co., Ltd
Tel
15714082442
Email
3757845877@qq.com
Country
China
ProdList
346
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
MedicalChem(Yancheng)Manuf.Co.,Ltd
Tel
+86-515-84383180
Fax
+86-515-84383182
Email
sales@medicalchem.com
Country
China
ProdList
80
Advantage
69
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
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View Lastest Price from thiosemicarbazide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Thiosemicarbazide 79-19-6
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000 KG
Release date
2021-06-03
Jinan Finer Chemical Co., Ltd
Product
N-Aminothiourea 79-19-6
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
200mt
Release date
2021-12-07
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
thiosemicarbazide 79-19-6
Price
US $999.00-800.00/ton
Min. Order
1ton
Purity
99%
Supply Ability
5000
Release date
2024-08-21

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