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inophyllum B

Product Name
inophyllum B
CAS No.
41135-06-2
Chemical Name
inophyllum B
Synonyms
inophyllum B;2H,6H,10H-Benzo[1,2-b:3,4-b':5,6-b'']tripyran-2-one, 11,12-dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-phenyl-, (10R,11S,12S)-
CBNumber
CB01336023
Molecular Formula
C25H24O5
Formula Weight
404.46
MOL File
41135-06-2.mol
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inophyllum B Property

Melting point:
58-62 °C
Boiling point:
564.7±50.0 °C(Predicted)
Density 
1.249±0.06 g/cm3(Predicted)
pka
13.37±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0015983
Product name
INOPHYLLUM B
Purity
95.00%
Packaging
5MG
Price
$497.83
Updated
2021/12/16
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inophyllum B Chemical Properties,Usage,Production

Uses

Inophyllum B ((+)-Inophyllum B) is a potent HIV Reverse Transcriptase inhibitor with an IC50 value of 38 nM. Inophyllum B inhibits HIV-1 (IC50=1.4 μM) in vitro cell culture. Inophyllum B can be isolated from the acetone extract of the giant African snail, Achatina fulica[1].

IC 50

HIV-1: 1.4 μM (IC50); Reverse Transcriptase: 38 nM (IC50)

References

[1] Patil AD, et al. The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn. J Med Chem. 1993 Dec 24;36(26):4131-8. DOI:10.1021/jm00078a001

inophyllum B Preparation Products And Raw materials

Raw materials

Preparation Products

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inophyllum B Suppliers

CHEMICAL LAND21
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South Korea
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