aphidicolin-17-monoacetate

Product Name: aphidicolin-17-monoacetate
CAS No.: 51103-57-2
Chemical Name: aphidicolin-17-monoacetate
Synonyms: Aphidicolin 17-acetate;aphidicolin-17-monoacetate;8,11a-Methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, 9-acetate, (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-
CBNumber: CB01355486
Molecular Formula: C22H36O5
Formula Weight: 380.52
MOL File: 51103-57-2.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Adipogen Life Sciences

Product number: BVT-0337-C250
Product name: Aphidicolin17-acetate
Purity: ≥96%(HPLC,1H-NMR)
Packaging: 250μg
Price: $90
Updated: 2021/12/16

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aphidicolin-17-monoacetate Chemical Properties,Usage,Production

Uses

Aphidicolin 17-acetate is a selective eukaryotic DNA polymerase α inhibitor. Aphidicolin 17-acetate does not inhibit DNA polymerase β and γ. Aphidicolin 17-acetate markedly inhibits the in vivo DNA synthesis of sea urchin embryos and HeLa cells but not RNA and protein syntheses[1].

References

[1] Haraguchi T, et al. Specific inhibitors of eukaryotic DNA synthesis and DNA polymerase alpha, 3-deoxyaphidicolin and aphidicolin-17-monoacetate. Nucleic Acids Res. 1983 Feb 25;11(4):1197-209. DOI:10.1093/nar/11.4.1197

aphidicolin-17-monoacetate Preparation Products And Raw materials

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Preparation Products

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51103-57-2, aphidicolin-17-monoacetateRelated Search:

APHIDICOLIN

aphidicolin-17-monoacetate

Aphidicolin 17-acetate

8,11a-Methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, 9-acetate, (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-

51103-57-2