Erucamide
- Product Name
- Erucamide
- CAS No.
- 112-84-5
- Chemical Name
- Erucamide
- Synonyms
- ERUCAMIDE;ERUCYLAMIDE;13-DOCOSENAMIDE;13Z-DOCOSENAMIDE;(Z)-docos-13-enamide;ERUCIC AMIDE;(z)-13-docosenamide;BYK-AT204;Erucic acid amide;CIS-13-DOCOSENAMIDE
- CBNumber
- CB0136080
- Molecular Formula
- C22H43NO
- Formula Weight
- 337.58
- MOL File
- 112-84-5.mol
Erucamide Property
- Melting point:
- 75-85 °C 79-81 °C (lit.)
- Boiling point:
- 473.86°C (rough estimate)
- Density
- 0.9417 (rough estimate)
- vapor pressure
- 0-0Pa at 25℃
- refractive index
- 1.5614 (estimate)
- Flash point:
- 230 °C
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (up to at lease 40 mg/ml) or in Water (up to at least 25 mg/ml with warming)
- form
- solid
- pka
- 16.61±0.40(Predicted)
- color
- Off-white
- Water Solubility
- PRACTICALLY INSOLUBLE
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChIKey
- UAUDZVJPLUQNMU-KTKRTIGZSA-N
- LogP
- 8
- CAS DataBase Reference
- 112-84-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 13-Docosenamide, (z)-(112-84-5)
- EPA Substance Registry System
- 13-Docosenamide, (13Z)- (112-84-5)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 1
- HS Code
- 29241990
- Hazardous Substances Data
- 112-84-5(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 280577
- Product name
- cis-13-Docosenoamide
- Packaging
- 5g
- Price
- $53
- Updated
- 2024/03/01
- Product number
- PHR3088
- Product name
- Plastic Additive 13
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 200MG
- Price
- $201
- Updated
- 2024/03/01
- Product number
- 1545045
- Product name
- Plastic additive 13
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 100mg
- Price
- $436
- Updated
- 2024/03/01
- Product number
- 90082
- Product name
- Erucamide
- Purity
- analytical standard
- Packaging
- 25MG
- Price
- $62.8
- Updated
- 2022/05/15
- Product number
- D1008
- Product name
- Erucamide
- Purity
- >85.0%(GC)
- Packaging
- 25g
- Price
- $51
- Updated
- 2024/03/01
Erucamide Chemical Properties,Usage,Production
Description
Erucamide is also known as 13-Docosenamide or Erucylamide. It is in the form of white flakes or beads. It is soluble in isopropanol, slightly soluble in alcohol and acetone.1 In industry, cis-13-docosenoamide is used in the formulations of anti-adhesive agents, lubricants, and lubricant additives to reduce their friction coefficient and to make films easier to handle.2 It is used as a standard to determine fatty acid amides in polyethylene packaging film by GC/MS.3
Chemical Properties
Erucamide is a fatty acid amide derived from erucic acid, which is found in vegetable oil. It is a odorless waxy solid that can dissolve in isopropanol and has low solubility in alcohol and acetone. It is also combustible. Its molecular structure consists of a long unsaturated C22 chain and a polar amine group, which gives it strong surface polarity, a high melting point, and good thermal stability. Because of these properties, it finds extensive applications in industries such as plastics, rubber, printing, and machinery.
Uses
Erucamide is primarily used as a polymer additive, with plastic additive 21 is a plasticizer; used in preparation of natural mineral modified degradable polymer flame-retardant composite material.
Preparation
Erucamide is prepared by reaction of erucic acid with anhydrous ammonia. The reaction of erucic acid with anhydrous ammonia is as follows: C22H42O2 + NH3 → C22H43NO2.
Definition
ChEBI: Erucamide is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia. It is commonly used as a slip additive in the plastic manufacturing industry. It has a role as a human metabolite, a rat metabolite, a mammalian metabolite, a plant metabolite and an EC 3.1.1.7 (acetylcholinesterase) inhibitor. It is functionally related to an erucic acid.
General Description
Erucamide is a migratory additive that is commonly placed in polyolefin films to reduce their coefficient of friction (COF), a good attribute for high speed packaging operations.
Biological Activity
13-Docosenamide is the amide of docosenoic acid. It was first identified in the cerebrospinal fluid of sleep-deprived cats. It has also been detected in the cerebrospinal fluid of rats and humans. 13-Docosenamide causes reduced mobility and slightly lessened awareness in rats, whereas 9-octadecenamide induces physiological sleep.
References
[1] MIAO-MIAO LI . Antidepressant and anxiolytic-like behavioral effects of erucamide, a bioactive fatty acid amide, involving the hypothalamus–pituitary–adrenal axis in mice[J]. Neuroscience Letters, 2017, 640: Pages 6-12. DOI:10.1016/j.neulet.2016.12.072.
[2] LIEROP B V, CASTLE L, FEIGENBAUM A, et al. Spectra for the Identification of Additives in Food Packaging[C]. 1998: 0. DOI:10.1007/978-94-011-5222-8.
[3] https://pubchem.ncbi.nlm.nih.gov/compound/Erucylamide#section=Use-and-Manufacturing
[4] https://www.sigmaaldrich.com/catalog/product/aldrich/280577?lang=de®ion=DE
[5] I. QUIJADA-GARRIDO. Desorption of Erucamide Vapor in Vacuum from Erucamide/Isotactic Polypropylene Films 1[J]. Macromolecules, 1996, 29 27: 8791-8797. DOI:10.1021/ma961065i.
Erucamide Preparation Products And Raw materials
Raw materials
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View Lastest Price from Erucamide manufacturers
- Product
- cis-13-Docosenoamide 112-84-5
- Price
- US $8040.00-8010.00/Metric tonnes
- Min. Order
- 1Metric tonnes
- Purity
- 98%
- Supply Ability
- 1000tons
- Release date
- 2023-02-14
- Product
- cis-13-Docosenoamide 112-84-5
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000 Ton
- Release date
- 2022-09-27
- Product
- cis-13-Docosenoamide 112-84-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99% HPLC
- Supply Ability
- 2000tons
- Release date
- 2019-12-30