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inulicin

Product Name
inulicin
CAS No.
33627-41-7
Chemical Name
inulicin
Synonyms
inulicin;Britannilactone;inulicin USP/EP/BP;Inulicin, 10 mM in DMSO;Inulicin(1-O-acetyl Britannilactone);1-O-Acetylbritannilactone (Inulicin);6-(3-acetoxy-propyl)-4-hydroxy-5,7-dimethyl-3-methylene-3,3a,4,5,8,8a-hexahydro-cyclohepta[b]furan-2-one;(S)-4-((3aS,4S,7aR)-4-Hydroxy-6-methyl-3-methylene-2-oxo-2,3,3a,4,7,7a-hexahydrobenzofuran-5-yl)pentyl acetate;(3aS)-6-(3-Acetoxypropyl)-3,3aα,4,5,8,8aα-hexahydro-4α-hydroxy-5α,7-dimethyl-3-methylene-2H-cyclohepta[b]furan-2-one;(3aS)-3,3aα,4,5,8,8aα-Hexahydro-4α-hydroxy-6-(3-acetoxypropyl)-5α,7-dimethyl-3-methylene-2H-cyclohepta[b]furan-2-one
CBNumber
CB01361911
Molecular Formula
C17H24O5
Formula Weight
308.37
MOL File
33627-41-7.mol
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inulicin Property

Melting point:
124.0-126.1 °C
Boiling point:
481.7±45.0 °C(Predicted)
Density 
1.16
storage temp. 
4°C, protect from light
solubility 
DMSO: soluble
form 
A solid
pka
13.71±0.60(Predicted)
color 
White to off-white
biological source
plant
Major Application
metabolomics
vitamins, nutraceuticals, and natural products
InChI
InChI=1S/C17H24O5/c1-9(6-5-7-21-12(4)18)14-10(2)8-13-15(16(14)19)11(3)17(20)22-13/h9,13,15-16,19H,3,5-8H2,1-2,4H3/t9-,13+,15+,16+/m0/s1
InChIKey
QKUFZFLZBUSEHN-CZLJMHDISA-N
SMILES
O1[C@]2([H])CC(C)=C([C@@H](C)CCCOC(C)=O)[C@@H](O)[C@]2([H])C(=C)C1=O
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Usbiological
Product number
361809
Product name
Inulicin
Packaging
10mg
Price
$708
Updated
2021/12/16
ChemScene
Product number
CS-3742
Product name
Inulicin
Purity
99.42%
Packaging
5mg
Price
$420
Updated
2021/12/16
ChemScene
Product number
CS-3742
Product name
Inulicin
Purity
99.42%
Packaging
1mg
Price
$160
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0001948
Product name
INULICIN
Purity
95.00%
Packaging
5MG
Price
$499.63
Updated
2021/12/16
Biorbyt Ltd
Product number
orb593692
Product name
Inulicin
Packaging
5mg
Price
$513.4
Updated
2021/12/16
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inulicin Chemical Properties,Usage,Production

Uses

Inulicin is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biological Activity

Inulicin (1-O-Acetylbritannilactone) is an active compound isolated from Inula Britannica L. It inhibits VEGF-mediated activation of Src and FAK. It also inhibits LPS-induced PGE2 production and COX-2 expression, as well as NF-κB activation and translocation.

in vivo

Administration of a single dose of Inulicin (1-O-Acetylbritannilactone; 12 mg/kg/day) remarkably suppresses growth of A549 xenografts in nude mice. In vivo microvessels formation and Src activation are also significantly inhibited in Inulicin-treated xenograft tumors. To investigate the potential activity of Inulicin in vivo, a nude mice xenograft model is applied.

target

NF-κB

< span>

COX-2

IC 50

NF-κB; COX-2

inulicin Preparation Products And Raw materials

Raw materials

Preparation Products

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inulicin Suppliers

Chengdu Biopurify Ltd.
Tel
82633860 18982077548
Email
cwb1@biopurify.cn
Country
China
ProdList
3870
Advantage
58
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5645
Advantage
65
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3988
Advantage
66
Chengdu Herbpurify Co.Ltd.
Tel
2355253622; 18981954830
Fax
086-28-85377358
Email
2355253622@qq.com;
Country
China
ProdList
1089
Advantage
58
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3921
Advantage
50
Shanghai Zhanshu Chemical Technology Co., Ltd
Tel
+86-21-58589556
Fax
+86-21-58589557
Country
China
ProdList
413
Advantage
55
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
Advantage
60
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View Lastest Price from inulicin manufacturers

Shanghai Standard Technology Co., Ltd.
Product
1-O-Acetylbritannilactone 33627-41-7
Price
US $0.00/mg
Min. Order
10mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-16

33627-41-7, inulicinRelated Search:


  • (3aS)-3,3aα,4,5,8,8aα-Hexahydro-4α-hydroxy-6-(3-acetoxypropyl)-5α,7-dimethyl-3-methylene-2H-cyclohepta[b]furan-2-one
  • (3aS)-6-(3-Acetoxypropyl)-3,3aα,4,5,8,8aα-hexahydro-4α-hydroxy-5α,7-dimethyl-3-methylene-2H-cyclohepta[b]furan-2-one
  • Britannilactone
  • (3aS,4S,7aR)-5-[(1S)-4-(Acetyloxy)-1-methylbutyl]-3a,4,7,7a-tetrahydro-4-hydroxy-6-methyl-3-methylene-2(3H)-benzofuranone
  • inulicin
  • 6-(3-acetoxy-propyl)-4-hydroxy-5,7-dimethyl-3-methylene-3,3a,4,5,8,8a-hexahydro-cyclohepta[b]furan-2-one
  • 1-O-Acetylbritannilactone (Inulicin)
  • 2(3H)-Benzofuranone,5-[(1S)-4-(acetyloxy)-1-methylbutyl]-3a,4,7,7a-tetrahydro-4-hydroxy-6-methyl-3-methylene-,(3aS,4S,7aR)-
  • Inulicin(1-O-acetyl Britannilactone)
  • inulicin USP/EP/BP
  • (S)-4-((3aS,4S,7aR)-4-Hydroxy-6-methyl-3-methylene-2-oxo-2,3,3a,4,7,7a-hexahydrobenzofuran-5-yl)pentyl acetate
  • Inulicin, 10 mM in DMSO
  • 33627-41-7