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inulicin

Product Name
inulicin
CAS No.
33627-41-7
Chemical Name
inulicin
Synonyms
inulicin;Britannilactone;inulicin USP/EP/BP;Inulicin(1-O-acetyl Britannilactone);1-O-Acetylbritannilactone (Inulicin);6-(3-acetoxy-propyl)-4-hydroxy-5,7-dimethyl-3-methylene-3,3a,4,5,8,8a-hexahydro-cyclohepta[b]furan-2-one;(S)-4-((3aS,4S,7aR)-4-Hydroxy-6-methyl-3-methylene-2-oxo-2,3,3a,4,7,7a-hexahydrobenzofuran-5-yl)pentyl acetate;(3aS)-6-(3-Acetoxypropyl)-3,3aα,4,5,8,8aα-hexahydro-4α-hydroxy-5α,7-dimethyl-3-methylene-2H-cyclohepta[b]furan-2-one;(3aS)-3,3aα,4,5,8,8aα-Hexahydro-4α-hydroxy-6-(3-acetoxypropyl)-5α,7-dimethyl-3-methylene-2H-cyclohepta[b]furan-2-one;(3aS,4S,7aR)-5-[(1S)-4-(Acetyloxy)-1-methylbutyl]-3a,4,7,7a-tetrahydro-4-hydroxy-6-methyl-3-methylene-2(3H)-benzofuranone
CBNumber
CB01361911
Molecular Formula
C17H24O5
Formula Weight
308.37
MOL File
33627-41-7.mol
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inulicin Property

Melting point:
124.0-126.1 °C
Boiling point:
481.7±45.0 °C(Predicted)
Density 
1.16
storage temp. 
4°C, protect from light
solubility 
DMSO: soluble
form 
A solid
pka
13.71±0.60(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
361809
Product name
Inulicin
Packaging
10mg
Price
$708
Updated
2021/12/16
ChemScene
Product number
CS-3742
Product name
Inulicin
Purity
99.42%
Packaging
5mg
Price
$420
Updated
2021/12/16
ChemScene
Product number
CS-3742
Product name
Inulicin
Purity
99.42%
Packaging
1mg
Price
$160
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0001948
Product name
INULICIN
Purity
95.00%
Packaging
5MG
Price
$499.63
Updated
2021/12/16
Biorbyt Ltd
Product number
orb593692
Product name
Inulicin
Packaging
5mg
Price
$513.4
Updated
2021/12/16
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inulicin Chemical Properties,Usage,Production

Biological Activity

Inulicin (1-O-Acetylbritannilactone) is an active compound isolated from Inula Britannica L. It inhibits VEGF-mediated activation of Src and FAK. It also inhibits LPS-induced PGE2 production and COX-2 expression, as well as NF-κB activation and translocation.

in vivo

Administration of a single dose of Inulicin (1-O-Acetylbritannilactone; 12 mg/kg/day) remarkably suppresses growth of A549 xenografts in nude mice. In vivo microvessels formation and Src activation are also significantly inhibited in Inulicin-treated xenograft tumors. To investigate the potential activity of Inulicin in vivo, a nude mice xenograft model is applied.

target

NF-κB

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COX-2

inulicin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from inulicin manufacturers

Shanghai Standard Technology Co., Ltd.
Product
1-O-Acetylbritannilactone 33627-41-7
Price
US $0.00/mg
Min. Order
10mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-16

33627-41-7, inulicinRelated Search:


  • (3aS)-3,3aα,4,5,8,8aα-Hexahydro-4α-hydroxy-6-(3-acetoxypropyl)-5α,7-dimethyl-3-methylene-2H-cyclohepta[b]furan-2-one
  • (3aS)-6-(3-Acetoxypropyl)-3,3aα,4,5,8,8aα-hexahydro-4α-hydroxy-5α,7-dimethyl-3-methylene-2H-cyclohepta[b]furan-2-one
  • Britannilactone
  • (3aS,4S,7aR)-5-[(1S)-4-(Acetyloxy)-1-methylbutyl]-3a,4,7,7a-tetrahydro-4-hydroxy-6-methyl-3-methylene-2(3H)-benzofuranone
  • inulicin
  • 6-(3-acetoxy-propyl)-4-hydroxy-5,7-dimethyl-3-methylene-3,3a,4,5,8,8a-hexahydro-cyclohepta[b]furan-2-one
  • 1-O-Acetylbritannilactone (Inulicin)
  • 2(3H)-Benzofuranone,5-[(1S)-4-(acetyloxy)-1-methylbutyl]-3a,4,7,7a-tetrahydro-4-hydroxy-6-methyl-3-methylene-,(3aS,4S,7aR)-
  • Inulicin(1-O-acetyl Britannilactone)
  • inulicin USP/EP/BP
  • (S)-4-((3aS,4S,7aR)-4-Hydroxy-6-methyl-3-methylene-2-oxo-2,3,3a,4,7,7a-hexahydrobenzofuran-5-yl)pentyl acetate
  • 33627-41-7