3-(2,4-dimethoxybenzylidene)anabaseine

Product Name: 3-(2,4-dimethoxybenzylidene)anabaseine
CAS No.: 156223-05-1
Chemical Name: 3-(2,4-dimethoxybenzylidene)anabaseine
Synonyms: DMXB;DMXB-A;DMBX-A;GTS-21HCl;GTS 21 2HCl;GTS-21 (DMXB-A);DMBX-anabaseine;GTS 21 2HCl(DMXBA);GTS21;GTS 21;GTS-21;GTS 21 2hydrochloride
CBNumber: CB01372542
Molecular Formula: C19H22Cl2N2O2
Formula Weight: 0
MOL File: 156223-05-1.mol

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3-(2,4-dimethoxybenzylidene)anabaseine Property

Melting point:: 216-217℃ (decomposition)
storage temp.: 2-8°C
solubility: H2O: >5mg/mL
form: powder
color: faint yellow to dark yellow
Water Solubility: H2O: >5mg/mL
InChIKey: RPYWXZCFYPVCNQ-RVDMUPIBSA-N

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Safety

WGK Germany: 3
RTECS: DW1764860

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0326
Product name: GTS-21
Purity: ≥97% (HPLC)
Packaging: 5mg
Price: $90.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0326
Product name: GTS-21
Purity: ≥97% (HPLC)
Packaging: 25mg
Price: $370
Updated: 2024/03/01

Sigma-Aldrich

Product number: 5.05277
Product name: GTS-21 Dihydrochloride (DMBX-A) - CAS 156223-05-1 - Calbiochem
Packaging: 10MG
Price: $108
Updated: 2022/05/15

Cayman Chemical

Product number: 21570
Product name: GTS-21 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $64
Updated: 2024/03/01

Cayman Chemical

Product number: 21570
Product name: GTS-21 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $113
Updated: 2024/03/01

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3-(2,4-dimethoxybenzylidene)anabaseine Chemical Properties,Usage,Production

Uses

GTS-21 has been used:

as an α7 nicotinic acetylcholine receptors (nAChR) partial agonist to elucidate its anti-inflammatory effects in mouse macrophages
to test its protective effect on the renal injury induced by lipopolysaccharide (LPS)
to test its effect on microvascular inflammation?in endotoxemia induced by LPS

Biochem/physiol Actions

GTS-2, a derivative of anisine is an immunomodulatory drug. It is used for treating pancreatitis and septicemia. GTS-2 inhibits the pro-inflammatory cytokines especially the interleukin-6 (IL6) and tumor necrosis factor (TNF) in sepsis and endotoxemia.

3-(2,4-dimethoxybenzylidene)anabaseine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(2,4-dimethoxybenzylidene)anabaseine Suppliers

China 81 South Korea 1 United Kingdom 1 United States 14 Global 97

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Wuhan Vanzpharm Inc.

Tel: 027-84492310 13657243668
Fax: 027-84492310
Email: wangting@vanzpharm.com
Country: China
ProdList: 50
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SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD

Tel: 13816107857
Fax: qq: 276312098
Email: sales@fortunechem-sh.com
Country: China
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MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Suzhou Pharmaceutical Technology co.,ltd

Tel: 0510-88771160 18051901298
Fax: 0510-8877116
Email: 2013446823@qq.com
Country: China
ProdList: 53
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Porse Fine Chemical Co.,LTD

Tel: 20-66003216 18666003216
Fax: +86-20-28069063
Email: info@porsefinechemical.com
Country: China
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Advantage: 62

Sigma-Aldrich

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Email: orderCN@merckgroup.com
Country: China
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D&C Chemicals

Tel: +86-21-58447131
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Email: 1724405207@qq.com
Country: China
ProdList: 472
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Advanced carbon Organic Pharm Co., Ltd.

Tel: +86-021-60528262
Fax: +86-021-64306513
Email: sales@acopharm.com
Country: China
ProdList: 94
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Beijing Autumn Biomedical Technology Co., Ltd

Tel: 010-80828512 18001163873
Email: wangcb2001@163.com
Country: China
ProdList: 58
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View Lastest Price from 3-(2,4-dimethoxybenzylidene)anabaseine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Gts-21 156223-05-1
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-29

Wuhan Haorong Biotechnology Co.,Ltd

Product: Dihydrochloride / 3-(2,4-dimethoxybenzylidene)anabaseine 156223-05-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000
Release date: 2023-08-11

Hebei Mujin Biotechnology Co.,Ltd

Product: Dihydrochloride / 3-(2,4-dimethoxybenzylidene)anabaseine 156223-05-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-10-10

156223-05-1, 3-(2,4-dimethoxybenzylidene)anabaseineRelated Search:

2-Methoxyphenylacetic acid 4'-Hydroxyacetophenone Sodium benzoate 3-(2,4-dimethoxybenzylidene)anabaseine

3-(2,4-dimethoxybenzylidene)anabaseine

3-[(3E)-3-[(2,4-dimethoxyphenyl)methylidene]-5,6-dihydro-4H-pyridin-2-yl]pyridine dihydrochloride

3-(2,4-Dimethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl

3-(2,4)-DiMethoxybenzylidineanabaseine

GTS-21 (DMXB-A)

3-(2,4-DiMethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl Dihydrochloride

(3E)-3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-Bipyridine dihydrochloride

DMBX-anabaseine

DMXB-A

GTS 21 DIHYDROCHLORIDE;DMXB-A;DMBX-ANABASEINE

GTS 21 2HCl(DMXBA)

GTS21;GTS 21;GTS-21

3-(2,4-Dimethoxybenzylidene)-anabaseine dihydrochloride

DMXB

GTS 21 dihydrochloride

3-[(2,4-dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-Bipyridine Dihydrochloride

GTS 21 2HCl

GTS 21 2hydrochloride

GTS-21 (hydrochloride)

GTS-21HCl

DMBX-A

(E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine dihydrochloride

3-(2,4-dimethoxybenzylidene)anabaseine / 99% / 156223-05-1 in sock

GTS 21 dihydrochloride(DMXB-A)

inhibit,5-hydroxytryptamine Receptor,anti?inflammatory,cognition,GTS-21,nAChR,GTS21 dihydrochloride,Serotonin Receptor,fibrosis,Inhibitor,GTS 21,5-HT Receptor,Nicotinic acetylcholine receptors,lung,injury,GTS21,pulmonary

Dihydrochloride / 3-(2,4-dimethoxybenzylidene)anabaseine

GTS-21 dihydrochloride (DMBX-A)

(E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine dihydrochloride

(E)-3-(2,4-dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine hydrochloride

3-(2,4-Dimethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl

GTS-21 dihydrochloride (DMBX-A), alpha7 Nicotinic acetylcholine receptor agonist

156223-05-1

C19H22Cl2N2O2

C19H20N2O22HCl

Inhibitors