5-Bromo-1-indanone
- Product Name
- 5-Bromo-1-indanone
- CAS No.
- 34598-49-7
- Chemical Name
- 5-Bromo-1-indanone
- Synonyms
- 5-BROMO-2,3-DIHYDRO-1H-INDEN-1-ONE;5-BROMO-1-INDANONE;E2DH;HSD17;AKR1C1;SDR9C2;EDH17B2;HSD17B2;2-ALPHA-HSD;20-ALPHA-HSD
- CBNumber
- CB0138796
- Molecular Formula
- C9H7BrO
- Formula Weight
- 211.06
- MOL File
- 34598-49-7.mol
5-Bromo-1-indanone Property
- Melting point:
- 126-129 °C(lit.)
- Boiling point:
- 303.7±31.0 °C(Predicted)
- Density
- 1.18 g/mL at 25 °C(lit.)
- refractive index
- 1.5720 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- form
- Powder
- color
- Beige to brown
- biological source
- rabbit
- BRN
- 2357199
- InChI
- InChI=1S/C9H7BrO/c10-7-2-3-8-6(5-7)1-4-9(8)11/h2-3,5H,1,4H2
- InChIKey
- KSONICAHAPRCMV-UHFFFAOYSA-N
- SMILES
- C1(=O)C2=C(C=C(Br)C=C2)CC1
- CAS DataBase Reference
- 34598-49-7(CAS DataBase Reference)
- NIST Chemistry Reference
- 1H-inden-1-one, 5-bromo-2,3-dihydro-(34598-49-7)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38-22
- Safety Statements
- 26-36-36/37/39
- WGK Germany
- 3
- Hazard Note
- Harmful
- HazardClass
- IRRITANT
- HS Code
- 29147000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SAB2700882
- Product name
- Anti-AKR1C1 antibody produced in rabbit
- Purity
- affinity isolated antibody, buffered aqueous solution
- Packaging
- 100μL
- Price
- $512
- Updated
- 2025/07/31
- Product number
- SAB1303130
- Product name
- ANTI-HSD17B2 (CENTER) antibody produced in rabbit
- Purity
- IgG fraction of antiserum, buffered aqueous solution
- Packaging
- 400μL
- Price
- $496
- Updated
- 2025/07/31
- Product number
- HPA068265
- Product name
- Anti-AKR1C1 antibody produced in rabbit
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody
- Packaging
- 100μL
- Price
- $598
- Updated
- 2025/07/31
- Product number
- 433098
- Product name
- 5-Bromo-1-indanone
- Purity
- 97%
- Packaging
- 1g
- Price
- $25.46
- Updated
- 2025/07/31
- Product number
- 433098
- Product name
- 5-Bromo-1-indanone
- Purity
- 97%
- Packaging
- 5g
- Price
- $116
- Updated
- 2025/07/31
5-Bromo-1-indanone Chemical Properties,Usage,Production
Description
5-Bromo-1-indanone is a 1-indanone derivative. Its physical properties like density, freezing point and refractive index have been determined. It participates in the synthesis of the imidazolyl and triazolyl substituted biphenyl compounds.
Chemical Properties
white to light yellow crystal powder
Uses
Starter for indanone-based pharmaceuticals1,2
Application
5-Bromo-1-indanone is a pharmaceutical intermediate compound that is a raw material for the preparation of indanone-based pharmaceuticals. It is also used as a chemical reagent for the preparation of other indanones such as 2,3,5 tribromoindanone by bromination[1].
General Description
5-Bromo-1-indanone is a 1-indanone derivative. Its physical properties like density, freezing point and refractive index have been determined. It participates in the synthesis of the imidazolyl and triazolyl substituted biphenyl compounds.
Synthesis
34598-50-0
34598-49-7
GENERAL STEPS: Be safe. Tert-butyl hydroperoxide (TBHP) is highly reactive, flammable and toxic, corrosive to skin and mucous membranes, and may cause respiratory distress by inhalation. A solution of 5-bromo-2,3-dihydro-1H-inden-1-ol (1 mmol) with 70% TBHP (6 or 10 equiv.) is reacted with stirring at 100°C for 24 hours. Upon completion of the reaction, the reaction mixture was quenched with saturated sodium thiosulfate solution (5 mL) and subsequently extracted with dichloromethane (3 x 10 mL). The combined dichloromethane extracts were dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure to remove the solvent. The residue was purified by rapid column chromatography on silica gel, and petroleum ether (PE) or mixed solvent of petroleum ether/ethyl acetate (PE/EtOAc) was selected as eluent to finally obtain 5-bromoindanone.
References
[1] TUTAR A, YILMAZ M, ERENLER R. Bromination of 4-bromoindanone and 5-bromoindanone[C]. 2013. DOI:10.5151/CHEMPRO-15BMOS-BMOS2013\_20131023104831.
5-Bromo-1-indanone Preparation Products And Raw materials
Raw materials
Preparation Products
5-Bromo-1-indanone Suppliers
- Tel
- --
- Fax
- --
- chemcontrol@nextra.sk
- Country
- Slovakia
- ProdList
- 6700
- Advantage
- 60
View Lastest Price from 5-Bromo-1-indanone manufacturers
- Product
- 5-Bromoindanone 34598-49-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13
- Product
- 5-Bromoindanone 34598-49-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2025-03-14
- Product
- 5-Bromo-1-indanone 34598-49-7
- Price
- US $36.00-1.50/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09