4-hydroxycyclohexylacetic acid
- Product Name
- 4-hydroxycyclohexylacetic acid
- CAS No.
- 99799-09-4
- Chemical Name
- 4-hydroxycyclohexylacetic acid
- Synonyms
- 4-hydroxycyclohexylacetic acid;4-hydroxycyclohexylacetic acidn;4-hydroxy-Cyclohexane acetic acid;Cyclohexaneacetic acid, 4-hydroxy-;2-(4-hydroxycyclohexyl)acetic acid;2-(4-Hydroxycyclohexyl)acetic acid (cis- and trans- );2-(4-Hydroxycyclohexyl)acetic Acid (cis- and trans- mixture)
- CBNumber
- CB01390786
- Molecular Formula
- C8H14O3
- Formula Weight
- 158.2
- MOL File
- 99799-09-4.mol
4-hydroxycyclohexylacetic acid Property
- Melting point:
- 110-120 °C
- Boiling point:
- 326.4±15.0 °C(Predicted)
- Density
- 1.166±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4.72±0.10(Predicted)
- color
- White to Off-White
- InChI
- InChI=1S/C8H14O3/c9-7-3-1-6(2-4-7)5-8(10)11/h6-7,9H,1-5H2,(H,10,11)
- InChIKey
- ALTAAUJNHYWOGS-UHFFFAOYSA-N
- SMILES
- C1(CC(O)=O)CCC(O)CC1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H1753
- Product name
- 2-(4-Hydroxycyclohexyl)acetic Acid (cis- and trans- mixture)
- Purity
- min. 98.0 %(total of isomers)
- Packaging
- 250MG
- Price
- $52
- Updated
- 2025/07/31
- Product number
- H1753
- Product name
- 2-(4-Hydroxycyclohexyl)acetic Acid (cis- and trans- mixture)
- Purity
- min. 98.0 %(total of isomers)
- Packaging
- 1G
- Price
- $128
- Updated
- 2025/07/31
- Product number
- H955215
- Product name
- 2-(4-Hydroxycyclohexyl)aceticAcid
- Packaging
- 100mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- CS-W021411
- Product name
- 2-(4-Hydroxycyclohexyl)aceticacid
- Packaging
- 1g
- Price
- $143
- Updated
- 2021/12/16
- Product number
- 128007
- Product name
- 2-(4-Hydroxycyclohexyl)aceticacid
- Purity
- 95%
- Packaging
- 1g
- Price
- $927
- Updated
- 2021/12/16
4-hydroxycyclohexylacetic acid Chemical Properties,Usage,Production
Uses
2-(4-Hydroxycyclohexyl)acetic Acid can be used to treat cancer and immunological and neurological disorders.
Definition
ChEBI: Cis-4-Hydroxycyclohexylacetic acid is a hydroxy monocarboxylic acid.
Synthesis
99183-13-8
99799-09-4
General procedure for the synthesis of 4-hydroxycyclohexylacetic acid from methyl (4-hydroxycyclohexyl)acetate: potassium hydroxide (326 mg) and methyl 2-(4-hydroxycyclohexyl)acetate (500 mg) were dissolved in a mixed solvent of methanol (20 mL) and water (20 mL), and the reaction was stirred for 6 hours at 60 °C. After completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure to remove most of the solvent. Subsequently, the pH was adjusted to 1 with 2 M hydrochloric acid solution, followed by extraction with ethyl acetate (50 mL). The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 4-hydroxycyclohexylacetic acid (150 mg) as a white solid. Mass spectrometry (ESI) analysis showed that the theoretical molecular weight of C8H14O3 was 158 and the measured value was 159 [M+H]+.
References
[1] Patent: WO2015/180613, 2015, A1. Location in patent: Page/Page column 16
[2] Patent: WO2015/180612, 2015, A1. Location in patent: Page/Page column 43
4-hydroxycyclohexylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
4-hydroxycyclohexylacetic acid Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from 4-hydroxycyclohexylacetic acid manufacturers
- Product
- 4-hydroxycyclohexylacetic acid 99799-09-4
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-24
- Product
- 2-(4-Hydroxycyclohexyl)acetic acid 99799-09-4
- Price
- US $0.00/gm
- Min. Order
- 100gm
- Purity
- 99%min
- Supply Ability
- 100kgs
- Release date
- 2024-09-03
- Product
- 4-hydroxycyclohexylacetic acid 99799-09-4
- Price
- US $60.00/Kg/Bag
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50kg/month
- Release date
- 2020-10-30