ChemicalBook > CAS DataBase List > 10-formyldihydrofolate

10-formyldihydrofolate

Product Name
10-formyldihydrofolate
CAS No.
28459-40-7
Chemical Name
10-formyldihydrofolate
Synonyms
C20H21N7O7;10-ForMyl-7;Folic acid IMpurity F;Folinic Acid IMpurity F;10-Formyldihyrofolic Acid;10-formyldihydrofolic acid;Folinic Acid EP Impurity F;Levofolinate EP Impurity F;Calcium Folinate EP Impurity F;Impurity F of Calcium Levofolinate
CBNumber
CB01393707
Molecular Formula
C20H21N7O7
Formula Weight
471.43
MOL File
28459-40-7.mol
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10-formyldihydrofolate Property

Density 
1.67±0.1 g/cm3(Predicted)
solubility 
Aqueous Acid (Slightly), Aqueous Base (Slightly)
pka
3.38±0.10(Predicted)
form 
Solid
color 
Orange to Very Dark Brown
Stability:
Hygroscopic, Temperature Sensitive
InChIKey
UXFQDXABPXWSTK-VHLFKADZNA-N
SMILES
O=C1N=C(N)NC2NCC(CN(C3C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=3)C=O)=NC1=2 |&1:19,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0294151
Product name
FOLIC ACID IMPURITY-F
Purity
95.00%
Packaging
5MG
Price
$500.98
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
40625
Product name
10-Formyl-7,8-dihydroFolicAcid(>85%)DisodiumSalt
Packaging
50mg
Price
$2400
Updated
2021/12/16
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10-formyldihydrofolate Chemical Properties,Usage,Production

Uses

10-Formyl-7,8-dihydrofolic acid is a novel folate found in methotrexate-treated cells. 10-Formyldihydrofolate (H2folate) has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells.

Definition

ChEBI: 10-formyldihydrofolic acid is the 10-formyl derivative of dihydrofolic acid. It is a conjugate acid of a 10-formyldihydrofolate(2-).

10-formyldihydrofolate Preparation Products And Raw materials

Raw materials

Preparation Products

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28459-40-7, 10-formyldihydrofolateRelated Search:

5,10-DiforMyl-5,6,7,8-tetrahydro Folic Acid 5,10-Methylene-THF (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid 10-Formylfolic Acid Calcium Levofolinate EP Impurity E Calcium levofolinate Folinic Acid IMpurity H Folinic Acid IMpurity E Calcium folinate Folinic Acid IMpurity G Folinic Acid IMpurity B IMp. D (EP): 4-[[(2-AMino-4-oxo-1,4-dihydropteridin-6-yl)Methyl]aMino]benzoic Acid (Pteroic Acid) O Folinic Acid IMpurity C Folic Acid Related Compound A/Calcium Formyltetrahydrofolate

  • Folinic Acid IMpurity F
  • Folic acid IMpurity F
  • 10-ForMyl-7,8-dihydro Folic Acid (>85%) DisodiuM Salt
  • C20H21N7O7
  • 10-ForMyl-7
  • 10-formyldihydrofolic acid
  • L-Glutamic acid,N-[4-[[(2-amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-
  • 10-Formyl-7,8-dihydro Folic Acid Disodium Salt
  • Folinic Acid EP Impurity F
  • Impurity F of Calcium Levofolinate
  • Levofolinate EP Impurity F
  • 10-Formyldihyrofolic Acid
  • 10-Formyl-7,8-dihydro Folic Acid Calcium Salt
  • Folinic Acid EP Impurity F Disodium Salt
  • Calcium Folinate EP Impurity F(10-Formyldihydrofolic Acid)
  • Calcium Folinate EP Impurity F
  • Folinic Acid EP Impurity F Calciume
  • 28459-40-7
  • 8459-40-7
  • Amines, Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals