GR231118

Product Name: GR231118
CAS No.: 158859-98-4
Chemical Name: GR231118
Synonyms: 1229U91;GR231118;NEUROPEPTIDE Y ANTAGONIST;M.W. 2352.77 C110H170N34O24;Amide Bridge=Glu2-Dap4*,Dap4-Glu2*;H-ILE-GLU-PRO-DAP-TYR-ARG-LEU-ARG-TYR-NH2;H-Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH2;ILE-GLU-PRO-DAPA-TYR-ARG-LEU-ARG-TYR-NH2, CYCLIC (2,4') (2',4) DIAMIDE;Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH2, cyclic (2,4') (2',4) diaMide (Dapa : diaMinopropionic acid);1229U91, Neuropeptide Y Antagonist, Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH2, cyclic (2,4μ)(2μ,4) diamide
CBNumber: CB0142308
Molecular Formula: C110H170N34O24
Formula Weight: 2352.74
MOL File: 158859-98-4.mol

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GR231118 Property

Density: 1.47±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: lyophilized powder

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1486
Product name: GR231118
Packaging: 500U
Price: $382
Updated: 2021/12/16

Usbiological

Product number: 255396
Product name: GR 231118
Packaging: 500ug
Price: $678
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0001648
Product name: GR231118
Purity: 95.00%
Packaging: 0.5MG
Price: $710.33
Updated: 2021/12/16

ApexBio Technology

Product number: B6760
Product name: GR231118
Packaging: 500ug
Price: $566
Updated: 2021/12/16

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GR231118 Chemical Properties,Usage,Production

Uses

GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8)[1].

IC 50

NPY Y₄ receptor

References

[1] E M Parker, et al. GR231118 (1229U91) and other analogues of the C-terminus of neuropeptide Y are potent neuropeptide Y Y1 receptor antagonists and neuropeptide Y Y4 receptor agonists. Eur J Pharmacol DOI:10.1016/s0014-2999(98)00171-x
[2] Y Dumont, et al. [(125)I]-GR231118: a high affinity radioligand to investigate neuropeptide Y Y(1) and Y(4) receptors. Br J Pharmacol.?2000 Jan;129(1):37-46. DOI:10.1038/sj.bjp.0702983

GR231118 Preparation Products And Raw materials

Raw materials

Preparation Products

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GR231118 Suppliers

China 35 Europe 1 France 1 Germany 3 Switzerland 1 United Kingdom 1 United States 8 USA 1 Global 51

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 4802
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7408
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 15397062932
Email: sales1@gotopbio.com
Country: China
ProdList: 2923
Advantage: 58

158859-98-4, GR231118Related Search:

Butanamide, 3-methyl-N-(4-oxo-4-(propylamino)butyl)- GR231118

1229U91

GR231118

H-ILE-GLU-PRO-DAP-TYR-ARG-LEU-ARG-TYR-NH2

ILE-GLU-PRO-DAPA-TYR-ARG-LEU-ARG-TYR-NH2, CYCLIC (2,4') (2',4) DIAMIDE

NEUROPEPTIDE Y ANTAGONIST

1229U91, Neuropeptide Y Antagonist, Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH2, cyclic (2,4μ)(2μ,4) diamide

M.W. 2352.77 C110H170N34O24

Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH2, cyclic (2,4') (2',4) diaMide (Dapa : diaMinopropionic acid)

L-Tyrosinamide, L-isoleucyl-L-α-glutamyl-L-prolyl-3-amino-L-alanyl-L-tyrosyl-L-arginyl-L-leucyl-L-arginyl-, bimol. (2→4'),(2'→4)-dilactam

Amide Bridge=Glu2-Dap4*,Dap4-Glu2*

H-Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH2

158859-98-4

C110H170N34O24

Neuropeptide Y

Neuropeptide Y and Peptide YY Peptides

Peptides

Biochemicals and Reagents

Amino Acids and Peptides

BioChemical

peptide

Neuropeptide Y (NPY ) receptor