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Furanodiene

Product Name: Furanodiene
CAS No.: 19912-61-9
Chemical Name: Furanodiene
Synonyms: Furanodiene;Furanodiene ISO 9001：2015 REACH;3,6,10-Trimethyl-4,7,8,11-tetrahydro-cyclodeca[B]furan;(5E)-3,6,10-Trimethyl-4,7,8,11-tetrahydrocyclodeca[B]furan;(5E,9Z)-4,7,8,11-Tetrahydro-3,6,10-trimethylcyclodeca[b]furan;Cyclodeca[B]furan, 4,7,8,11-tetrahydro-3,6,10-trimethyl-, (5E)-;Cyclodeca[b]furan, 4,7,8,11-tetrahydro-3,6,10-trimethyl-, (5E,9Z)-;Inchi=1/C15H20o/C1-11-5-4-6-12(2)9-15-14(8-7-11)13(3)10-16-15/H6-7,10H,4-5,8-9H2,1-3H3/B11-7+,12-6
CBNumber: CB01470547
Molecular Formula: C15H20O
Formula Weight: 216.32
MOL File: 19912-61-9.mol

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Furanodiene Property

Melting point:: 74-75 °C
Boiling point:: 309.6±11.0 °C(Predicted)
Density: 0.945±0.06 g/cm3(Predicted)
form: Solid
color: Off-white to light yellow
LogP: 5.369 (est)
CAS DataBase Reference: 19912-61-9

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Hazard and Precautionary Statements (GHS)

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Furanodiene Chemical Properties,Usage,Production

Uses

Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae. Furanodiene plays anti-cancer effects through anti-angiogenesis and inducing ROS production, DNA strand breaks and apoptosis. Furanodiene suppresseed efflux transporter Pgp (P-glycoprotein) function and reduced Pgp protein level[1].

Hazard

A poison by ingestion.

Anticancer Research

Tested on uterine cervical (UI4) and sarcoma 180 (S180) tumors in mice, the furanodienehas a significant tumor inhibition rate dose-dependent. The furanodienewas administered intraperitoneally as liposome. The effect of furanodiene on theinhibition of cell proliferation by activation of apoptosis was not hypothesized(Song et al. 2014, Zielińska and Matkowski 2014, Polo et al. 2013).

References

[1] Xiao-Yu Zhu, et al. Sensitization and synergistic anti-cancer effects of Furanodiene identified in zebrafish models. Sci Rep. 2019 Mar 14;9(1):4541. DOI:10.1038/s41598-019-40866-2

Furanodiene Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Furanodiene manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Furanodiene 19912-61-9
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-23

19912-61-9, FuranodieneRelated Search:

(1alpha,2beta,4beta)-1-methyl-2,4-bis(methylvinyl)-1-vinylcyclohexane Furanodienone Sodium nifurstylenate Curzerenone Furanodiene Furanadiene-standard substance Furandiene standard (3Z,7Z)-3,7,11-trimethyl-13-oxabicyclo[8.3.0]trideca-3,7,11,14-tetraene

Furanodiene

(5E)-3,6,10-Trimethyl-4,7,8,11-tetrahydrocyclodeca[B]furan

3,6,10-Trimethyl-4,7,8,11-tetrahydro-cyclodeca[B]furan

Cyclodeca[B]furan, 4,7,8,11-tetrahydro-3,6,10-trimethyl-, (5E)-

Inchi=1/C15H20o/C1-11-5-4-6-12(2)9-15-14(8-7-11)13(3)10-16-15/H6-7,10H,4-5,8-9H2,1-3H3/B11-7+,12-6

(5E,9Z)-4,7,8,11-Tetrahydro-3,6,10-trimethylcyclodeca[b]furan

Cyclodeca[b]furan, 4,7,8,11-tetrahydro-3,6,10-trimethyl-, (5E,9Z)-

Furanodiene ISO 9001：2015 REACH

19912-61-9