ChemicalBook > CAS DataBase List > Furanodiene

Furanodiene

Product Name
Furanodiene
CAS No.
19912-61-9
Chemical Name
Furanodiene
Synonyms
Furanodiene;Furanodiene ISO 9001：2015 REACH;3,6,10-Trimethyl-4,7,8,11-tetrahydro-cyclodeca[B]furan;(5E)-3,6,10-Trimethyl-4,7,8,11-tetrahydrocyclodeca[B]furan;(5E,9Z)-4,7,8,11-Tetrahydro-3,6,10-trimethylcyclodeca[b]furan;Cyclodeca[B]furan, 4,7,8,11-tetrahydro-3,6,10-trimethyl-, (5E)-;Cyclodeca[b]furan, 4,7,8,11-tetrahydro-3,6,10-trimethyl-, (5E,9Z)-;Inchi=1/C15H20o/C1-11-5-4-6-12(2)9-15-14(8-7-11)13(3)10-16-15/H6-7,10H,4-5,8-9H2,1-3H3/B11-7+,12-6
CBNumber
CB01470547
Molecular Formula
C15H20O
Formula Weight
216.32
MOL File
19912-61-9.mol
More
Less

Furanodiene Property

Melting point:
74-75 °C
Boiling point:
309.6±11.0 °C(Predicted)
Density 
0.945±0.06 g/cm3(Predicted)
form 
Solid
color 
Off-white to light yellow
LogP
5.369 (est)
CAS DataBase Reference
19912-61-9
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

Furanodiene Chemical Properties,Usage,Production

Uses

Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae. Furanodiene plays anti-cancer effects through anti-angiogenesis and inducing ROS production, DNA strand breaks and apoptosis. Furanodiene suppresseed efflux transporter Pgp (P-glycoprotein) function and reduced Pgp protein level[1].

Hazard

A poison by ingestion.

Anticancer Research

Tested on uterine cervical (UI4) and sarcoma 180 (S180) tumors in mice, the furanodienehas a significant tumor inhibition rate dose-dependent. The furanodienewas administered intraperitoneally as liposome. The effect of furanodiene on theinhibition of cell proliferation by activation of apoptosis was not hypothesized(Song et al. 2014, Zielińska and Matkowski 2014, Polo et al. 2013).

References

[1] Xiao-Yu Zhu, et al. Sensitization and synergistic anti-cancer effects of Furanodiene identified in zebrafish models. Sci Rep. 2019 Mar 14;9(1):4541. DOI:10.1038/s41598-019-40866-2

Furanodiene Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Furanodiene Suppliers

China 47 United States 2 USA 1 Global 50
More
Less

View Lastest Price from Furanodiene manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Furanodiene 19912-61-9
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-23

19912-61-9, FuranodieneRelated Search:

(1alpha,2beta,4beta)-1-methyl-2,4-bis(methylvinyl)-1-vinylcyclohexane Furanodienone Sodium nifurstylenate Curzerenone Furanodiene Furanadiene-standard substance Furandiene standard (3Z,7Z)-3,7,11-trimethyl-13-oxabicyclo[8.3.0]trideca-3,7,11,14-tetraene

  • Furanodiene
  • (5E)-3,6,10-Trimethyl-4,7,8,11-tetrahydrocyclodeca[B]furan
  • 3,6,10-Trimethyl-4,7,8,11-tetrahydro-cyclodeca[B]furan
  • Cyclodeca[B]furan, 4,7,8,11-tetrahydro-3,6,10-trimethyl-, (5E)-
  • Inchi=1/C15H20o/C1-11-5-4-6-12(2)9-15-14(8-7-11)13(3)10-16-15/H6-7,10H,4-5,8-9H2,1-3H3/B11-7+,12-6
  • (5E,9Z)-4,7,8,11-Tetrahydro-3,6,10-trimethylcyclodeca[b]furan
  • Cyclodeca[b]furan, 4,7,8,11-tetrahydro-3,6,10-trimethyl-, (5E,9Z)-
  • Furanodiene ISO 9001：2015 REACH
  • 19912-61-9