2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one

Product Name: 2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one
CAS No.: 135302-13-5
Chemical Name: 2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one
Synonyms: Triazole moiety;5-Methoxy-4-Methyl-1,2,4-triazolinone;3-Methoxy-4-methyl-1H-1,2,4-triazol-5-one;Thiencarbazone-methyl Metabolite AE1277106;3-Methoxy-4-Methyl-1H-1,2,4-triazol-5(4H)-one;5-methoxy-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one;3H-1,2,4-triazol-3-one,2,4-dihydro-5-methoxy-4-methyl;2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one;2.4-Dihydro-5-methoxy-4-methy-3H-1,2.4-triazol-3-one(MMT)
CBNumber: CB01483642
Molecular Formula: C4H7N3O2
Formula Weight: 129.12
MOL File: 135302-13-5.mol

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2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one Property

Melting point:: 138 - 140°C
Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly, Sonicated), Methanol (Slightly), Water (Slightly, Sonicated)
form: Solid
pka: 6.85±0.20(Predicted)
color: White to Off-White
InChI: InChI=1S/C4H7N3O2/c1-7-3(8)5-6-4(7)9-2/h1-2H3,(H,5,8)
InChIKey: AMHDHUVBOKXALL-UHFFFAOYSA-N
SMILES: N1=C(OC)N(C)C(=O)N1
LogP: -0.6--0.5 at 24-25℃ and pH5-9
Dissociation constant: 10.4 at 25℃
EPA Substance Registry System: 3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-methoxy-4-methyl- (135302-13-5)

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Ark Pharm

Product number: P000046038
Product name: 3-Methoxy-4-methyl-1H-1,2,4-triazol-5(4H)-one
Purity: 97%
Packaging: 250mg
Price: $10
Updated: 2021/12/16

Ark Pharm

Product number: P000046038
Product name: 3-Methoxy-4-methyl-1H-1,2,4-triazol-5(4H)-one
Purity: 97%
Packaging: 1g
Price: $23
Updated: 2021/12/16

AK Scientific

Product number: J97039
Product name: 3-Methoxy-4-methyl-1H-1,2,4-triazol-5(4H)-one
Packaging: 5g
Price: $60
Updated: 2021/12/16

Ark Pharm

Product number: P000046038
Product name: 3-Methoxy-4-methyl-1H-1,2,4-triazol-5(4H)-one
Purity: 97%
Packaging: 5g
Price: $71
Updated: 2021/12/16

Ark Pharm

Product number: P000046038
Product name: 3-Methoxy-4-methyl-1H-1,2,4-triazol-5(4H)-one
Purity: 97%
Packaging: 10g
Price: $119
Updated: 2021/12/16

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2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one Chemical Properties,Usage,Production

Uses

2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one is a white powder and is mainly used as a pesticide intermediate.

Uses

is used in process for the preparation of herbicide Thiencarbazone-Me in the presence of substituted Imidazole.

Synthesis

222163-50-0

135302-13-5

Example 7 Preparation of 5-methoxy-4-methyl-2,4-dihydro-1,2,4-triazol-3-one: 4.77 g (25.0 mmol) of methyl N'-dimethoxymethylidenehydrazine carboxylate (85% purity) was mixed with 15.3 g of 51% methanol solution of methylamine (containing 250 mmol of methylamine), and stirred at room temperature for 3 days. After completion of the reaction, the orange-red solution was concentrated under reduced pressure to remove excess methylamine to give the crude product methyl N'-(methoxymethylaminomethylene) hydrazine carboxylate. The crude product was dissolved in 15 ml of methanol, 4.95 g (27.5 mmol) of a methanolic solution of 30% sodium methanolate was added, and the reaction was heated to 50 °C for 3 h 50 min. After the reaction mixture was cooled to room temperature, it was neutralized with 2N HCl and concentrated under reduced pressure. The residue was dissolved in 6 ml of water and placed in a refrigerator overnight for crystallization. Colorless crystals were collected by filtration, washed with cold water and dried under reduced pressure to give 1.70 g (52.7% yield) of 5-methoxy-4-methyl-2,4-dihydro-1,2,4-triazol-3-one as a colorless solid with a melting point of 146-148 °C.

References

[1] Patent: US6248900, 2001, B1
[2] Patent: US6248900, 2001, B1

2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one Suppliers

China 93 India 1 United States 5 Global 99

Weifang Yuan Ye Biotechnology Co., Ltd.

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View Lastest Price from 2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one 135302-13-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-10

Henan Fengda Chemical Co., Ltd

Product: 2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one 135302-13-5
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-16

Weifang Yuanye Biotechnology Co., Ltd

Product: 3H-1,2,4-triazol-3-one,2,4-dihydro-5-methoxy-4-methyl 135302-13-5
Price: US $0.00/KG
Min. Order: 25KG
Purity: 98%
Supply Ability: 500MT
Release date: 2021-04-10

135302-13-5, 2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-oneRelated Search:

2-Methyl-4-isothiazolin-3-one 2-(Chloromethyl)-4,5-dihydro-1H-imidazole hydrochloride Cobalt tetramethoxyphenylporphyrin

2,4-Dihydro-5-methoxy-4-methyl-3H-1,2,4-triazol-3-one

3-Methoxy-4-Methyl-1H-1,2,4-triazol-5(4H)-one

5-Methoxy-4-Methyl-1,2,4-triazolinone

Triazole moiety

3H-1,2,4-triazol-3-one,2,4-dihydro-5-methoxy-4-methyl

Thiencarbazone-methyl Metabolite AE1277106

5-methoxy-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one

3-Methoxy-4-methyl-1H-1,2,4-triazol-5-one

2.4-Dihydro-5-methoxy-4-methy-3H-1,2.4-triazol-3-one(MMT)

135302-13-5