ChemicalBook > CAS DataBase List > 4-IODO-2-PYRIDONE

4-IODO-2-PYRIDONE

Product Name
4-IODO-2-PYRIDONE
CAS No.
858839-90-4
Chemical Name
4-IODO-2-PYRIDONE
Synonyms
4-IODO-2-PYRIDONE;4-Iodo-2-pyridinone;4-Iodopyridin-2(1H);4-Iodo-2(1H)-pyridinone;4-iodo-2-pyridone , 97+%;4-Iodo-2-hydroxypyridine;2-Hydroxy-4-iodopyridine;2(1H)-Pyridinone, 4-iodo-;4-iodo-1,2-dihydropyridin-2-one
CBNumber
CB01486870
Molecular Formula
C5H4INO
Formula Weight
221
MOL File
858839-90-4.mol
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4-IODO-2-PYRIDONE Property

Melting point:
186-188°C
Boiling point:
321.6±35.0 °C(Predicted)
Density 
2.12±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
solid
pka
10.76±0.10(Predicted)
color 
Pale brown
CAS DataBase Reference
858839-90-4
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
I737683
Product name
4-Iodopyridin-2(1H)-one
Packaging
500mg
Price
$240
Updated
2021/12/16
TRC
Product number
I737683
Product name
4-Iodopyridin-2(1H)-one
Packaging
100mg
Price
$65
Updated
2021/12/16
SynQuest Laboratories
Product number
4H17-H-01
Product name
4-Iodo-1H-pyridin-2-one
Purity
97%
Packaging
1g
Price
$314
Updated
2021/12/16
Matrix Scientific
Product number
077035
Product name
4-Iodo-1,2-dihydropyridin-2-one
Purity
95%
Packaging
500mg
Price
$262
Updated
2021/12/16
Apolloscientific
Product number
OR12279
Product name
4-Iodo-1H-pyridin-2-one
Purity
97%
Packaging
1g
Price
$285
Updated
2021/12/16
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4-IODO-2-PYRIDONE Chemical Properties,Usage,Production

Synthesis

153034-86-7

858839-90-4

GENERAL METHOD: 2-chloro-4-iodopyridine (prepared above) was heated with sodium acetate (2.0 eq.) in 1.0 M acetic acid solution at 150°C for 72 hours in a sealed tube. After completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure. The residue was partitioned between ethyl acetate (3 mL/mmol) and cold water (3 mL/mmol). The aqueous layer was extracted with ethyl acetate (3 mL/mmol; 4 times). The combined organic layers were washed sequentially with saturated NaHCO3 solution (1 mL/mmol), brine, dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. The crude product was purified by silica gel fast column chromatography to afford 4-iodo-2-pyridinone (1b/c/d), details of the specific compound are given below.

References

[1] Synlett, 2016, vol. 27, # 1, p. 67 - 69
[2] Patent: US2010/331320, 2010, A1. Location in patent: Page/Page column 89; 90
[3] Patent: WO2015/101928, 2015, A1. Location in patent: Page/Page column 48
[4] Patent: WO2012/32014, 2012, A1. Location in patent: Page/Page column 94
[5] Patent: US2012/214782, 2012, A1. Location in patent: Page/Page column 40

4-IODO-2-PYRIDONE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-IODO-2-PYRIDONE manufacturers

Career Henan Chemical Co
Product
4-IODO-2-PYRIDONE 858839-90-4
Price
US $5.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-01-12

858839-90-4, 4-IODO-2-PYRIDONERelated Search:


  • 4-IODO-2-PYRIDONE
  • 4-Iodo-2(1H)-pyridinone
  • 4-Iodo-2-hydroxypyridine
  • 4-iodo-2-pyridone , 97+%
  • 4-iodo-1,2-dihydropyridin-2-one
  • 2-Hydroxy-4-iodopyridine
  • 4-Iodopyridin-2(1H)
  • 4-Iodo-2-pyridinone
  • 2(1H)-Pyridinone, 4-iodo-
  • 858839-90-4
  • Halides
  • Pyridines