PIPERIDINE-1-SULFONYL CHLORIDE
- Product Name
- PIPERIDINE-1-SULFONYL CHLORIDE
- CAS No.
- 35856-62-3
- Chemical Name
- PIPERIDINE-1-SULFONYL CHLORIDE
- Synonyms
- Piperidine-1-Sulfonic Acid;Piperidinosulfonyl chloride;Piperidinesulfonyl chloride;1-Piperidinesulfonylchloride;Piperadine-1-sulfonylchloride;Piperidin-1-sulfonyl chloride;N-piperidinylsulfaMoyl chloride;Piperidine-1-sulfonylchloride,97%;Piperidine-1-sulfonyl chloride 96%;piperidine-1-sulfonyl chloride(SALTDATA: FREE)
- CBNumber
- CB01491373
- Molecular Formula
- C5H10ClNO2S
- Formula Weight
- 183.66
- MOL File
- 35856-62-3.mol
PIPERIDINE-1-SULFONYL CHLORIDE Property
- Boiling point:
- 120℃ (10 Torr)
- Density
- 1.308 g/mL at 25 °C
- refractive index
- 1.4920
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- -8.25±0.20(Predicted)
- form
- liquid
- color
- Dark brown
- Sensitive
- Moisture Sensitive
- InChIKey
- QQJYAXDCMMXECR-UHFFFAOYSA-N
- CAS DataBase Reference
- 35856-62-3
Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3265 8 / PGII
- WGK Germany
- 3
- HazardClass
- 8
- HazardClass
- IRRITANT
- PackingGroup
- Ⅱ
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 749354
- Product name
- Piperidine-1-sulfonyl chloride
- Purity
- 96%
- Packaging
- 1g
- Price
- $155
- Updated
- 2025/07/31
- Product number
- P475350
- Product name
- Piperidine-1-sulfonyl chloride
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- P475350
- Product name
- Piperidine-1-sulfonyl chloride
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- Z4648
- Product name
- Piperidine-1-sulfonyl chloride
- Packaging
- 5g
- Price
- $81
- Updated
- 2021/12/16
- Product number
- OR933169
- Product name
- Piperidine-1-sulfonyl chloride
- Purity
- 97%
- Packaging
- 1g
- Price
- $102
- Updated
- 2021/12/16
PIPERIDINE-1-SULFONYL CHLORIDE Chemical Properties,Usage,Production
Uses
Piperidine-1-sulfonyl chloride is used as pharmaceutical intermediate.
Synthesis
110-89-4
35856-62-3
Example 1: Synthesis of piperidine-1-sulfonyl chloride A mixture of piperidine (100 g, 1.17 mol) and triethylamine (178 g, 1.76 mol) in dichloromethane (500 ml) was slowly added to a solution of sulfuryl chloride (238 g, 1.76 mol) in dichloromethane (500 ml) at 0 °C - 5 °C. The reaction mixture was gradually warmed to room temperature and stirred continuously for 2 hours. After completion of the reaction, the mixture was quenched by pouring into ice water. The organic layer was separated and washed with distilled water (2 x 5 v/v). The organic layer was dried over anhydrous sodium sulfate and the solvent was evaporated under reduced pressure to give an oily residue (151.3 g, 70% yield). The resulting product was characterized by nuclear magnetic resonance hydrogen spectroscopy (H NMR): H NMR (300 MHz, CDCl3) δ = 1.58-1.62 (m, 2H), 1.69-1.83 (m, 4H), 3.31-3.42 (m, 4H).
References
[1] Patent: WO2015/83066, 2015, A1. Location in patent: Page/Page column 11-12
[2] Journal of Fluorine Chemistry, 1982, vol. 20, p. 425 - 438
[3] Patent: WO2005/87721, 2005, A2. Location in patent: Page/Page column 81-82
[4] Archiv der Pharmazie (Weinheim, Germany), 1958, vol. 291, p. 7,11
[5] Bulletin de la Societe Chimique de France, 1936, vol. <5> 3, p. 2143,2146, 2149, 2150
PIPERIDINE-1-SULFONYL CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from PIPERIDINE-1-SULFONYL CHLORIDE manufacturers
- Product
- PIPERIDINE-1-SULFONYL CHLORIDE 35856-62-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-08