ChemicalBook > CAS DataBase List > 4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
- Product Name
- 4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
- CAS No.
- 334969-03-8
- Chemical Name
- 4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
- Synonyms
- ON01210;Recilisib;Recilisib sodium;Recilisib sodium salt;Recilisib (free acid);Recilisib, 10 mM in DMSO;Recilisib sodium(ON01210);4-Chlorobenzyl-4-carboxystyryl sulfone;(E)-4-(2-((4-Chlorobenzyl)sulfonyl)vinyl)benzoic acid;4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
- CBNumber
- CB01501926
- Molecular Formula
- C16H13ClO4S
- Formula Weight
- 336.79
- MOL File
- 334969-03-8.mol
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4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID Property
- Boiling point:
- 607.8±55.0 °C(Predicted)
- Density
- 1.423±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 35.71 mg/mL (106.03 mM)
- form
- Solid
- pka
- 4.00±0.10(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-6712
- Product name
- Recilisib
- Purity
- 98.94%
- Packaging
- 5mg
- Price
- $110
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6712
- Product name
- Recilisib
- Purity
- 98.94%
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6712
- Product name
- Recilisib
- Purity
- 98.94%
- Packaging
- 25mg
- Price
- $250
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6712
- Product name
- Recilisib
- Purity
- 98.94%
- Packaging
- 50mg
- Price
- $450
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- HCH0353724
- Product name
- 4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.18
- Updated
- 2021/12/16
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4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID Chemical Properties,Usage,Production
Uses
Recilisib (ON 01210) is a radioprotectant, which can activate AKT, PI3K activities in cells[1].
Biological Activity
Recilisib is a radioprotectant that activates the activity of AKT and PI3K in cells.
in vivo
Recilisib Sodium (500 mg/kg) significantly increases the rate of recovery and differentiation of primitive bone marrow myeloid progenitor cells in mice. It in combination with radiation reduces CFU numbers in mice, but the Recilisib Sodium-treated mice consistently retain a capability to form differentiated colonies.
target
| Akt
| PI3K
|