ChemicalBook > CAS DataBase List > 4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID

4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID

Product Name
4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
CAS No.
334969-03-8
Chemical Name
4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
Synonyms
ON01210;Recilisib;Recilisib sodium;Recilisib sodium salt;Recilisib sodium(ON01210);4-Chlorobenzyl-4-carboxystyryl sulfone;4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID;Benzoic acid, 4-[(1E)-2-[[(4-chlorophenyl)methyl]sulfonyl]ethenyl]-;PI3K,ON-01210,PKB,Akt,ON01210,Recilisib,Protein kinase B,inhibit,Phosphoinositide 3-kinase,Inhibitor
CBNumber
CB01501926
Molecular Formula
C16H13ClO4S
Formula Weight
336.79
MOL File
334969-03-8.mol
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4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID Property

Boiling point:
607.8±55.0 °C(Predicted)
Density 
1.423±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 35.71 mg/mL (106.03 mM)
pka
4.00±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-6712
Product name
Recilisib
Purity
98.94%
Packaging
5mg
Price
$110
Updated
2021/12/16
ChemScene
Product number
CS-6712
Product name
Recilisib
Purity
98.94%
Packaging
10mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-6712
Product name
Recilisib
Purity
98.94%
Packaging
25mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-6712
Product name
Recilisib
Purity
98.94%
Packaging
50mg
Price
$450
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0353724
Product name
4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
Purity
95.00%
Packaging
5MG
Price
$502.18
Updated
2021/12/16
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4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID Chemical Properties,Usage,Production

Biological Activity

Recilisib is a radioprotectant that activates the activity of AKT and PI3K in cells.

in vivo

Recilisib Sodium (500 mg/kg) significantly increases the rate of recovery and differentiation of primitive bone marrow myeloid progenitor cells in mice. It in combination with radiation reduces CFU numbers in mice, but the Recilisib Sodium-treated mice consistently retain a capability to form differentiated colonies.

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4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID Suppliers

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334969-03-8, 4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACIDRelated Search:

4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID

  • Recilisib sodium salt
  • Recilisib sodium
  • Recilisib sodium(ON01210)
  • 4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
  • Recilisib
  • ON01210
  • 4-Chlorobenzyl-4-carboxystyryl sulfone
  • Benzoic acid, 4-[(1E)-2-[[(4-chlorophenyl)methyl]sulfonyl]ethenyl]-
  • PI3K,ON-01210,PKB,Akt,ON01210,Recilisib,Protein kinase B,inhibit,Phosphoinositide 3-kinase,Inhibitor
  • 334969-03-8

    • Akt

    PI3K