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Dimethocaine Hydrochloride

Product Name
Dimethocaine Hydrochloride
CAS No.
553-63-9
Chemical Name
Dimethocaine Hydrochloride
Synonyms
diMethocaine hcl;Larocaine HCl;Larocaine hydrochloride;Dimethylcaine hydrochloride;3-(diethylamino)-2;Dimethyl hydrochloride;Dimethocaine hydrochloride;Dimethocaine/Larocaine hcl;1-Propanol,3-(diethylamino)-2;3-Diethylamino-2,2-dimethylpropyl p-amin...
CBNumber
CB01509593
Molecular Formula
C16H26N2O2.ClH
Formula Weight
314.854
MOL File
553-63-9.mol
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Dimethocaine Hydrochloride Property

Melting point:
195-196℃
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Water (Slightly)
form 
Solid
color 
White to Pale Beige
InChI
InChI=1S/C16H26N2O2.ClH/c1-5-18(6-2)11-16(3,4)12-20-15(19)13-7-9-14(17)10-8-13;/h7-10H,5-6,11-12,17H2,1-4H3;1H
InChIKey
WWTWKTDXBNHESE-UHFFFAOYSA-N
SMILES
C1(=CC=C(N)C=C1)C(=O)OCC(C)(C)CN(CC)CC.Cl
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Safety

Toxicity
MLD in mice, rabbits (g/kg): 0.30, 0.15 s.c.; 0.04, 0.015 i.v. (Hirschfelder, Bieter)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
11159
Product name
Dimethocaine (hydrochloride)
Purity
≥98%
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
11159
Product name
Dimethocaine (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$270
Updated
2024/03/01
Cayman Chemical
Product number
11159
Product name
Dimethocaine (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$477
Updated
2024/03/01
Usbiological
Product number
010123
Product name
Dimethocaine Hydrochloride
Packaging
25mg
Price
$460
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD22163
Product name
3-Diethylamino-2,2-dimethylpropyl p-aminobenzoate hydrochloride
Packaging
50g
Price
$430
Updated
2021/12/16
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Dimethocaine Hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A local anesthetic with stimulant properties. Studies have shown its potency to be about half that of Cocaine (C633500).

Uses

Dimethocaine Hydrochloride is a local anesthetic, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 μM comparable to that of cocaine (IC50 = 0.7 μM). As a result, dimethocaine dose-dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys. This product is intended for forensic and research purposes.[Cayman Chemical]

Application

Dimethocaine Hydrochloride is a drug that belongs to the amide class. It has been shown to have significant effects on neuronal function in vivo, as well as on dopamine neurotransmission in vitro. It is also a substrate for uptake by the dopamine transporter and can inhibit locomotor activity in rats, suggesting it may be a potential therapeutic agent for the treatment of Parkinson's disease. It has been shown to be effective against cocaine addiction and can reduce angiogenic factors in vivo. The drug also interacts with other drugs, including synthetic cannabinoids and amphetamines, which are metabolized by CYP2B6 enzymes. These interactions may result in reduced efficacy of Dimethocaine Hydrochloride therapy.

Side effects

Its positive effects are euphoria, stimulation, increased talkativeness and mood lift. However, because the drug acts similar as cocaine, it has comparable negative side effects. These side effects include: tachycardia, difficulty with breathing, pain on the chest, vasoconstriction, insomnia, paranoia and anxiety.

Dimethocaine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Dimethocaine Hydrochloride Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Nanjing JinruiJiuAn Biotechnology Co., Ltd.
Tel
025-58196018 800028039
Fax
025-83453306
Email
sales@fartop.net
Country
China
ProdList
2229
Advantage
55
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9346
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9649
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Hangzhou Dingyan Chem Co., LTD
Tel
0571-87157530-8002 15267169049
Fax
0571-87156470
Email
sales@dingyanchem.com
Country
China
ProdList
2190
Advantage
58
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
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View Lastest Price from Dimethocaine Hydrochloride manufacturers

Dorne Chemical Technology co. LTD
Product
Dimethocaine Hydrochloride 553-63-9
Price
US $10.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
1 ton
Release date
2024-03-26
Hebei Miaoyin Technology Co.,Ltd
Product
Dimethocaine Hydrochloride 553-63-9
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000 Kilogram/Kilograms per Day
Release date
2023-03-07
Hebei Yanxi Chemical Co., Ltd.
Product
Dimethocaine Hydrochloride 553-63-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg
Release date
2023-08-09

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