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Dimethocaine Hydrochloride

Product Name
Dimethocaine Hydrochloride
CAS No.
553-63-9
Chemical Name
Dimethocaine Hydrochloride
Synonyms
diMethocaine hcl;Larocaine HCl;Larocaine hydrochloride;Dimethylcaine hydrochloride;3-(diethylamino)-2;Dimethyl hydrochloride;Dimethocaine hydrochloride;Dimethocaine/Larocaine hcl;1-Propanol,3-(diethylamino)-2;3-Diethylamino-2,2-dimethylpropyl p-amin...
CBNumber
CB01509593
Molecular Formula
C16H26N2O2.ClH
Formula Weight
314.854
MOL File
553-63-9.mol
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Dimethocaine Hydrochloride Property

Melting point:
195-196℃
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Water (Slightly)
form 
Solid
color 
White to Pale Beige
InChI
InChI=1S/C16H26N2O2.ClH/c1-5-18(6-2)11-16(3,4)12-20-15(19)13-7-9-14(17)10-8-13;/h7-10H,5-6,11-12,17H2,1-4H3;1H
InChIKey
WWTWKTDXBNHESE-UHFFFAOYSA-N
SMILES
C1(=CC=C(N)C=C1)C(=O)OCC(C)(C)CN(CC)CC.Cl
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Safety

Toxicity
MLD in mice, rabbits (g/kg): 0.30, 0.15 s.c.; 0.04, 0.015 i.v. (Hirschfelder, Bieter)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
11159
Product name
Dimethocaine (hydrochloride)
Purity
≥98%
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
11159
Product name
Dimethocaine (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$270
Updated
2024/03/01
Cayman Chemical
Product number
11159
Product name
Dimethocaine (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$477
Updated
2024/03/01
Usbiological
Product number
010123
Product name
Dimethocaine Hydrochloride
Packaging
25mg
Price
$460
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD22163
Product name
3-Diethylamino-2,2-dimethylpropyl p-aminobenzoate hydrochloride
Packaging
50g
Price
$430
Updated
2021/12/16
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Dimethocaine Hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A local anesthetic with stimulant properties. Studies have shown its potency to be about half that of Cocaine (C633500).

Uses

Dimethocaine Hydrochloride is a local anesthetic, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 μM comparable to that of cocaine (IC50 = 0.7 μM). As a result, dimethocaine dose-dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys. This product is intended for forensic and research purposes.[Cayman Chemical]

Application

Dimethocaine Hydrochloride is a drug that belongs to the amide class. It has been shown to have significant effects on neuronal function in vivo, as well as on dopamine neurotransmission in vitro. It is also a substrate for uptake by the dopamine transporter and can inhibit locomotor activity in rats, suggesting it may be a potential therapeutic agent for the treatment of Parkinson's disease. It has been shown to be effective against cocaine addiction and can reduce angiogenic factors in vivo. The drug also interacts with other drugs, including synthetic cannabinoids and amphetamines, which are metabolized by CYP2B6 enzymes. These interactions may result in reduced efficacy of Dimethocaine Hydrochloride therapy.

Side effects

Its positive effects are euphoria, stimulation, increased talkativeness and mood lift. However, because the drug acts similar as cocaine, it has comparable negative side effects. These side effects include: tachycardia, difficulty with breathing, pain on the chest, vasoconstriction, insomnia, paranoia and anxiety.

Dimethocaine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Dimethocaine Hydrochloride Suppliers

Canada 1 China 110 France 1 Germany 1 India 1 United Kingdom 1 United States 4 Global 119
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19639
Advantage
58
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View Lastest Price from Dimethocaine Hydrochloride manufacturers

Dorne Chemical Technology co. LTD
Product
Dimethocaine Hydrochloride 553-63-9
Price
US $10.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
1 ton
Release date
2024-03-26
Hebei Yanxi Chemical Co., Ltd.
Product
Dimethocaine Hydrochloride 553-63-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg
Release date
2023-08-09
Hebei Ganmiao New material Technology Co., LTD
Product
Dimethocaine Hydrochloride 553-63-9
Price
US $10.00-8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-06

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