8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL
- Product Name
- 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL
- CAS No.
- 59108-43-9
- Chemical Name
- 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL
- Synonyms
- BUTTPARK 91\04-55;8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL;8-broMo-2-(trifluoroMethyl)-4-quinolinone;4-Quinolinol, 8-bromo-2-(trifluoromethyl)-;2-Trifluoromethyl-4-hydroxy-8-bromoquinoline;8-BroMo-4-hydroxy-2-(trifluoroMethyl)quinoline;-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;8-bromo-2-(trifluoromethyl)quinolin-4-ol, 95%, HC-6749;8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL ISO 9001:2015 REACH
- CBNumber
- CB0151243
- Molecular Formula
- C10H5BrF3NO
- Formula Weight
- 292.05
- MOL File
- 59108-43-9.mol
8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL Property
- Melting point:
- 136 °C
- Boiling point:
- 354.6±37.0 °C(Predicted)
- Density
- 1.771±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 6.16±0.40(Predicted)
- CAS DataBase Reference
- 59108-43-9
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 075504
- Product name
- 8-Bromo-4-hydroxy-2-(trifluoromethyl)quinoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $231
- Updated
- 2021/12/16
- Product number
- W7202
- Product name
- 8-Bromo-4-hydroxy-2-(trifluoromethyl)quinoline
- Packaging
- 10g
- Price
- $304
- Updated
- 2021/12/16
- Product number
- 075504
- Product name
- 8-Bromo-4-hydroxy-2-(trifluoromethyl)quinoline
- Purity
- 95+%
- Packaging
- 5g
- Price
- $639
- Updated
- 2021/12/16
- Product number
- HCH0025421
- Product name
- 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $831.6
- Updated
- 2021/12/16
- Product number
- 075504
- Product name
- 8-Bromo-4-hydroxy-2-(trifluoromethyl)quinoline
- Purity
- 95+%
- Packaging
- 10g
- Price
- $929
- Updated
- 2021/12/16
8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL Chemical Properties,Usage,Production
Synthesis
372-31-6
615-36-1
587885-87-8
Step 1: Ethyl trifluoroacetoacetate (10 g, 58.5 mmol) was slowly added dropwise to a mixture of o-bromoaniline (10.7 g, 58.5 mmol) and polyphosphoric acid (PPA, 40 g) at 100 °C for a controlled time of less than 15 min. After the dropwise addition, the reaction mixture was warmed up to 150 °C with continuous stirring for 12 hours. After completion of the reaction, it was cooled to room temperature and the reaction mixture was diluted with 10 wt% sodium hydroxide solution (160 mL). The precipitate was collected by filtration and the filtrate was acidified with concentrated hydrochloric acid. The precipitate was collected by filtration again and recrystallized with ethanol to give the target compound 140-3 (10.5 g, 62% yield) as a white solid. Mass spectrometry (ESI) analysis: C10H5BrF3NO [M + H]+ calculated value 292, measured value 292.
References
[1] European Journal of Organic Chemistry, 2003, # 8, p. 1576 - 1588
[2] Patent: EP3124482, 2017, A1. Location in patent: Paragraph 0281; 0282
8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL manufacturers
- Product
- 8-Bromo-2-(Trifluoromethyl)Quinolin-4-OL 59108-43-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.9%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL 59108-43-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10 tons
- Release date
- 2020-01-10