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5-nitrobenzofuran

Product Name
5-nitrobenzofuran
CAS No.
18761-31-4
Chemical Name
5-nitrobenzofuran
Synonyms
5-nitrobenzofuran;Benzofuran, 5-nitro-;5-Nitro-[2,3]-benzofuran
CBNumber
CB01515811
Molecular Formula
C8H5NO3
Formula Weight
163.13
MOL File
18761-31-4.mol
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5-nitrobenzofuran Property

Melting point:
114-115 °C
Boiling point:
273.1±13.0 °C(Predicted)
Density 
1.380±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly)
form 
Solid
Appearance
Off-white to light yellow Solid
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Safety

HS Code 
2932209090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific
Product number
OR111026
Product name
5-Nitro-1-benzofuran
Packaging
1g
Price
$318
Updated
2021/12/16
SynQuest Laboratories
Product number
4H54-1-DZ
Product name
5-Nitro-1-benzofuran
Packaging
1g
Price
$351
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0156098
Product name
5-NITRO-1-BENZOFURAN
Purity
95.00%
Packaging
1MG
Price
$597.89
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0156098
Product name
5-NITRO-1-BENZOFURAN
Purity
95.00%
Packaging
10MG
Price
$631.85
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0156098
Product name
5-NITRO-1-BENZOFURAN
Purity
95.00%
Packaging
5MG
Price
$633.99
Updated
2021/12/16
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5-nitrobenzofuran Chemical Properties,Usage,Production

Uses

5-Nitro-1-benzofuran is a chemical reagent used in the synthesis of internal alkynes. Also used in the preparation of anti-oxidants quinolines.

Synthesis

77123-61-6

18761-31-4

Step 1c. Synthesis of 5-nitrobenzofuran (Compound 104): a mixture of (2-fluoro-5-nitrophenyl)ethynyltrimethylsilane (Compound 103, 7.30 g, 30.8 mmol), sodium acetate (10.1 g, 123 mmol), and N,N-dimethylformamide (70 mL) was stirred and reacted for 16 hours at 100 °C. After completion of the reaction, the precipitate was collected by filtration and washed with N,N-dimethylformamide. The filtrates were combined and the solvent was removed by evaporation to give the crude product. The crude product was purified by short silica gel column chromatography (eluent: ethyl acetate/petroleum ether=1/10) to afford the title compound 104 as a brown solid (3.0 g, 60% yield).

References

[1] Patent: US2009/76044, 2009, A1. Location in patent: Page/Page column 25

5-nitrobenzofuran Preparation Products And Raw materials

Raw materials

Preparation Products

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5-nitrobenzofuran Suppliers

Achemica
Tel
--
Fax
--
Email
contact@achemica.com
Country
Switzerland
ProdList
6155
Advantage
50
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View Lastest Price from 5-nitrobenzofuran manufacturers

Career Henan Chemical Co
Product
5-nitrobenzofuran 18761-31-4
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
200kg
Release date
2020-03-05