2,5-dibromo-4-nitro-1H-imidazole Property

Melting point:

>270 °C

Boiling point:

396℃

Density 

2.575

Flash point:

193℃

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

2.93±0.10(Predicted)

CAS DataBase Reference

6154-30-9

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2,5-dibromo-4-nitro-1H-imidazole Chemical Properties,Usage,Production

Description

2,5-dibromo-4-nitro-1H-imidazole is an important intermediate in the synthesis of bactericidal drug Delamanid, and 2-bromo-4-nitroimidazole (II) is also used to synthesize other nitroimidazoles under development.

Uses

2,4-Dibromo-5-nitro-1H-imidazole is an intermediate in organic synthesis and pharmaceutical intermediate, which can be used in laboratory research and development process and chemical production process.

Preparation

After reacting 4-nitroimidazole with sodium bicarbonate, bromine was added to finally obtain 2,5-dibromo-4-nitro-1H-imidazole.