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5-bromothiophene-3-carboxylic acid

Product Name
5-bromothiophene-3-carboxylic acid
CAS No.
100523-84-0
Chemical Name
5-bromothiophene-3-carboxylic acid
Synonyms
5-BroMo-3-thiophenecarboxylic acid;EA159;5-Bromothiophene-3-carboxylicaci;2-Bromothiophene-4-carboxylic acid;5-bromothiophene-3-carboxylic acid;3-Thiophenecarboxylic acid, 5-broMo-;5-Bromothiophene-3-carboxylic acid 97+%;5-Bromothiophene-3-carboxylic acid≥ 97% (HPLC);5-bromothiophene-3-carboxylic acid ISO 9001:2015 REACH
CBNumber
CB01529504
Molecular Formula
C5H3BrO2S
Formula Weight
207.05
MOL File
100523-84-0.mol
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5-bromothiophene-3-carboxylic acid Property

Melting point:
140-144°C
Boiling point:
318.9±27.0 °C(Predicted)
Density 
1.923±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
solid
pka
3.82±0.10(Predicted)
color 
Off-white
InChI
InChI=1S/C5H3BrO2S/c6-4-1-3(2-9-4)5(7)8/h1-2H,(H,7,8)
InChIKey
YCNXGPMGMAKDPM-UHFFFAOYSA-N
SMILES
C1SC(Br)=CC=1C(O)=O
CAS DataBase Reference
100523-84-0
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
774227
Product name
5-bromothiophene-3-carboxylic acid
Purity
97%
Packaging
1g
Price
$218
Updated
2023/06/20
TRC
Product number
B698993
Product name
5-bromothiophene-3-carboxylic acid
Packaging
250mg
Price
$100
Updated
2021/12/16
Apolloscientific
Product number
OR17257
Product name
5-Bromothiophene-3-carboxylic acid
Packaging
1g
Price
$27
Updated
2021/12/16
SynQuest Laboratories
Product number
6H66-9-08
Product name
5-Bromothiophene-3-carboxylic acid
Purity
99%
Packaging
1g
Price
$32
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB154213
Product name
5-Bromothiophene-3-carboxylic acid
Packaging
500mg
Price
$55
Updated
2021/12/16
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5-bromothiophene-3-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Synthesis

88-13-1

100523-84-0

(d) Synthesis of 5-bromo-3-thiophenecarboxylic acid: a glacial acetic acid solution of bromine was prepared by dissolving 16 g of Br2 (0.1 mol) in 200 ml of glacial acetic acid. This solution was slowly added dropwise to 100 ml of glacial acetic acid solution containing 3-thiophenecarboxylic acid (12.8 g; 0.1 mol). The reaction mixture was stirred at room temperature for 20 minutes. Upon completion of the reaction, the mixture was poured into a vessel containing water and ice to quench the reaction and promote precipitation of the product. The resulting white precipitate was collected by filtration and washed with water to remove residual glacial acetic acid. Finally, the product was purified by recrystallization from water to give 5-bromo-3-thiophenecarboxylic acid in 70% yield.

References

[1] Tetrahedron Letters, 2013, vol. 54, # 11, p. 1460 - 1462
[2] Patent: US4767758, 1988, A
[3] Journal of Materials Chemistry C, 2018, vol. 6, # 14, p. 3731 - 3742
[4] Chemistry of Materials, 2010, vol. 22, # 19, p. 5617 - 5624
[5] Angewandte Chemie - International Edition, 2018, vol. 57, # 26, p. 7714 - 7718

5-bromothiophene-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-bromothiophene-3-carboxylic acid Suppliers

A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 5-bromothiophene-3-carboxylic acid manufacturers

R&D Scientific Inc.
Product
5-Bromo-3-thiophenecarboxylic Acid 100523-84-0
Price
US $590.00/g
Min. Order
1g
Purity
99 %
Supply Ability
5000 Kg
Release date
2025-11-04
Shenzhen Nexcon Pharmatechs Ltd.
Product
5-bromothiophene-3-carboxylic acid 100523-84-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
2000
Release date
2025-06-11
Hebei Fengjia New Material Co., Ltd
Product
5-bromothiophene-3-carboxylic acid 100523-84-0
Price
US $5.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2024-08-14

100523-84-0, 5-bromothiophene-3-carboxylic acidRelated Search:


  • 5-BroMo-3-thiophenecarboxylic acid
  • 5-Bromothiophene-3-carboxylic acid≥ 97% (HPLC)
  • 5-bromothiophene-3-carboxylic acid
  • 3-Thiophenecarboxylic acid, 5-broMo-
  • 5-Bromothiophene-3-carboxylic acid 97+%
  • 2-Bromothiophene-4-carboxylic acid
  • 5-bromothiophene-3-carboxylic acid ISO 9001:2015 REACH
  • EA159
  • 5-Bromothiophene-3-carboxylicaci
  • 100523-84-0