ChemicalBook > CAS DataBase List > 2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine

2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine

Product Name
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
CAS No.
230615-69-7
Chemical Name
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
Synonyms
Vernicline Di amine;Varenicline Impurity 15;Varenicline Impurity 25;Valenciennes intermediate;Varenicline ortho-Diamino Impurity;Varenicline Diamine Impurity - Bio-X ?;1-(7,8-diamino-1,2,4,5-tetrahydro-1,5-methano-3H-3-benzazepi...;2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine;1-(4,5-diamino-10-azabicyclo[6.3.1]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoroethanone;1,5-Methano-1H-3-benzazepine-7,8-diamine, 2,3,4,5-tetrahydro-3-(trifluoroacetyl)- (9CI)
CBNumber
CB01562446
Molecular Formula
C13H14F3N3O
Formula Weight
285.27
MOL File
230615-69-7.mol
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2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine Property

Melting point:
83-88°C
Boiling point:
487.7±45.0 °C(Predicted)
Density 
1.455
storage temp. 
Refrigerator, Under Inert Atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
pka
4.86±0.20(Predicted)
color 
White to Brown
InChI
InChI=1S/C13H14F3N3O/c14-13(15,16)12(20)19-4-6-1-7(5-19)9-3-11(18)10(17)2-8(6)9/h2-3,6-7H,1,4-5,17-18H2
InChIKey
LWZYCQINJXEWRC-UHFFFAOYSA-N
SMILES
C(=O)(N1CC2CC(C3=CC(N)=C(N)C=C32)C1)C(F)(F)F
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
T295985
Product name
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
Packaging
100mg
Price
$55
Updated
2021/12/16
TRC
Product number
T295985
Product name
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
Packaging
1g
Price
$155
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD11985
Product name
1-(7,8-Diamino-1,2,4,5-tetrahydro-1,5-methano-3H-3-benzazepin-3-yl)-2,2,2-trifluoroethanone
Packaging
250mg
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD11985
Product name
1-(7,8-Diamino-1,2,4,5-tetrahydro-1,5-methano-3H-3-benzazepin-3-yl)-2,2,2-trifluoroethanone
Packaging
500mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD11985
Product name
1-(7,8-Diamino-1,2,4,5-tetrahydro-1,5-methano-3H-3-benzazepin-3-yl)-2,2,2-trifluoroethanone
Packaging
1g
Price
$180
Updated
2021/12/16
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2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine Chemical Properties,Usage,Production

Chemical Properties

Brownish Orange Solid

Uses

Varenicline intermediate.

Application

2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine is a reactant used in the preparation of Varenicline, a nicotinic α4β2 acetylcholine receptor partial agonist. Aid in smoking cessation.

2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine Suppliers

T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Anhui Qiushi Medical Technology Co., Ltd
Tel
15005516438
Fax
15005516438
Email
sales1@qiushipharm.com
Country
China
ProdList
82
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
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58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
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Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
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50
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7471
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China Langchem Inc.
Tel
0086-21-58956006
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0086-21-58956100
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China
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7811
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Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
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58
Xunteng International Trading Co.,Limited
Tel
Country
China Hong Kong
ProdList
878
Advantage
55
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View Lastest Price from 2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine 230615-69-7
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-25
Moxin Chemicals
Product
Varenicline Impurity 230615-69-7
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98
Supply Ability
100000000000
Release date
2024-12-03
Career Henan Chemical Co
Product
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine 230615-69-7
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-05-23

230615-69-7, 2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamineRelated Search:


  • 1-(4,5-Diamino-10-aza-tricyclo[6.3.1.0]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoro-ethanone
  • 1,5-Methano-1H-3-benzazepine-7,8-diamine, 2,3,4,5-tetrahydro-3-(trifluoroacetyl)- (9CI)
  • 1-(7,8-diamino-1,2,4,5-tetrahydro-1,5-methano-3H-3-benzazepin-3-yl)-2,2,2-trifluoroethanone
  • 2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
  • 1-(7,8-diaMino-4,5-dihydro-1H-1,5-Methanobenzo[d]azepin-3(2H)-yl)-2,2,2-trifluoroethanone
  • Ethanone,1-(7,8-diamino-1,2,4,5-tetrahydro-1,5-methano-3H-3-benzazepin-3-yl)-2,2,2-trifluoro-
  • 1-(4,5-diamino-10-azabicyclo[6.3.1]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoroethanone
  • Varenicline Impurity 15
  • Varenicline ortho-Diamino Impurity
  • Varenicline Impurity 25
  • 1-(7,8-diamino-1,2,4,5-tetrahydro-1,5-methano-3H-3-benzazepi...
  • Vernicline Di amine
  • 1-(4,5-diamino-10-azatricyclo[6.3.1.02,7]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoroethanone
  • 2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine,230615-69-7
  • Varenicline Diamine Impurity - Bio-X ?
  • Valenciennes intermediate
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