7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)

Product Name: 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)
CAS No.: 230615-70-0
Chemical Name: 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)
Synonyms: C1sH2F3N3O;Vernicline API TFA;Vanillin ring complex;Varenicline Impurity 16;Varenicline Impurity 19;-2,2,2-trifluoroethanone;Varenicline N-Trifluoroacetyl;Varenicline N-Trifluoroacetyl Impurity;1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H);2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-6,10-methano-8H-pyraz...
CBNumber: CB51512572
Molecular Formula: C15H12F3N3O
Formula Weight: 307.27
MOL File: 230615-70-0.mol

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7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) Property

Melting point:: 164-166 ºC
Boiling point:: 491.9±45.0 °C(Predicted)
Density: 1.449
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 1.50±0.20(Predicted)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T889503
Product name: 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine
Packaging: 50mg
Price: $425
Updated: 2021/12/16

ChemScene

Product number: CS-B0007
Product name: 1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H)-yl)-2,2,2-trifluoroethanone
Purity: 98.95%
Packaging: 100mg
Price: $458
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0029454
Product name: 7,8,9,10-TETRAHYDRO-8-(TRIFLUOROACETYL)-6,10-METHANO-6H-PYRAZINO[2,3-H][3]BENZAZEPINE
Purity: 95.00%
Packaging: 5MG
Price: $504.45
Updated: 2021/12/16

Matrix Scientific

Product number: 098972
Product name: 1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]-quinoxalin-8(7H)-yl)-2,2,2-trifluoroethanone
Purity: 95+%
Packaging: 250mg
Price: $567
Updated: 2021/12/16

AK Scientific

Product number: 1495AB
Product name: 1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H)-yl)-2,2,2-trifluoroethanone
Packaging: 250mg
Price: $815
Updated: 2021/12/16

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7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) Chemical Properties,Usage,Production

Description

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(trifluoroacetyl)varenicline) is an important pharmaceutical intermediate compound which is used in the preparation of varenicline. Varenicline is an oral smoking cessation aid drug. It works by blocking the pleasant effects of nicotine (from smoking) on the brain.

Uses

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine is used to prepare varenicline, which is a smoking cessation. It is a Varenicline protected impurity.

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) Preparation Products And Raw materials

Raw materials

Preparation Products

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7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) Suppliers

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View Lastest Price from 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) manufacturers

Career Henan Chemical Co

Product: 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacety 230615-70-0
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-19

230615-70-0, 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)Related Search:

Varenicline Impurity 5 (+/-)-2,2,2-trifluoro-1-(4-nitro-10-aza-tricyclo[6.3.1.02,7]dodeca-2(7),3,5-trien-10-yl)-ethanone Varenicline Impurity 17 N-Methyl Varenicline 5,9-Methanoimidazo[4,5-h][3]benzazepine,1,5,6,7,8,9-hexahydro-(9CI) Varenicline-13C2,15N2 Varenicline Impurity 13 HCl N-Acetyl Varenicline N-Formyl Varenicline Varenicline-d4 2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine 2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine 7,8,9,10-Tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine 1,4-Dioxide 10-AZA-TRICYCLO[6.3.1.0]DODECA-2,4,6-TRIENE TOSYLATE 2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) Varenicline 6,7-DIMETHYLQUINOXALINE

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)- (9CI)

2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)ethanone

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)-

10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)-

1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]-quinoxalin-8(7H)-yl)-2,2,2-trifluoroethanone

2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)ethan-1-one

1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H)

-2,2,2-trifluoroethanone

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacety

2,2,2 - trifluoro - 1 - (6,7,9,10-tetrahydro- 8H - 6,10 -methanoazepino [4,5-g]quinoxaline- 8 - yl) ethan - 1 - one

Varenicline Impurity 16

Ethanone, 2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)-

Varenicline Impurity 19

Varenicline N-Trifluoroacetyl Impurity

2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-6,10-methano-8H-pyraz...

Vernicline API TFA

8-(Trifluoroacetyl)-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)

Varenicline N-Trifluoroacetyl

C1sH2F3N3O

Vanillin ring complex

230615-70-0

API intermediates