Amezinium methylsulfate
- Product Name
- Amezinium methylsulfate
- CAS No.
- 30578-37-1
- Chemical Name
- Amezinium methylsulfate
- Synonyms
- lu1631;Risumic;regulton;Tenfortan;Amezinium;Supratonin;REGULTON (KNOLL);Amezinium mesylate;RISUMIC (DAINIPPON);ameziniometilsulfato
- CBNumber
- CB0166074
- Molecular Formula
- C12H15N3O5S
- Formula Weight
- 313.33
- MOL File
- 30578-37-1.mol
Amezinium methylsulfate Property
- Melting point:
- 176° (dec)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO : ≥ 34 mg/mL (108.51 mM)
- form
- powder to crystal
- color
- White to Light yellow
- Merck
- 14,394
- CAS DataBase Reference
- 30578-37-1
Safety
- RTECS
- UR6066500
- HS Code
- 2933.59.8000
- Toxicity
- LD50 in mice, rats (mg/kg): 1630, 1410 orally; 40.4, 45.5 i.v. (Teschendorf)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A2425
- Product name
- Amezinium Methyl Sulfate
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $40
- Updated
- 2024/03/01
- Product number
- A2425
- Product name
- Amezinium Methyl Sulfate
- Purity
- >98.0%(HPLC)
- Packaging
- 5g
- Price
- $195
- Updated
- 2024/03/01
- Product number
- FA29468
- Product name
- Amezinium methyl sulfate
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FA29468
- Product name
- Amezinium methyl sulfate
- Packaging
- 2g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 37582
- Product name
- Ameziniummethylsulfate,≥98%(HPLC)
- Purity
- ≥98%(HPLC)
- Packaging
- 5G
- Price
- $354.1
- Updated
- 2021/12/16
Amezinium methylsulfate Chemical Properties,Usage,Production
Originator
Regulton,Nordmark,W. Germany,1981
Definition
ChEBI: Amezinium metilsulfate is an azaheterocycle sulfate salt of amezinium. It is a sympathomimetic drug which suppresses noradrenaline reuptake and thereby elevating blood pressure. It is used for the treatment of low blood pressure in patients undergoing dialysis. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor, an antihypotensive agent, a sympathomimetic agent and an adrenergic uptake inhibitor. It contains an amezinium.
Manufacturing Process
18.7 parts of 1-phenyl-4-aminopyridazone-(6) and 19 parts of dimethyl sulfate in 400 parts of xylene are kept at 120°C for one hour while mixing well. The reaction mixture is suction filtered, 28 parts (89.5% of the theory) of 1-phenyl-4-amino-6-methoxypyridazinium methosulfate is obtained having a melting point of 173°C to 174°C after recrystallization from acetonitrile. The perchlorate has a melting point of 179°C to 182°C.
Therapeutic Function
Antihypotensive
Amezinium methylsulfate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Amezinium methylsulfate manufacturers
- Product
- Amezinium Methyl Sulfate 30578-37-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- Amezinium methylsulfate 30578-37-1
- Price
- US $1.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 95.0-99.8%
- Supply Ability
- 1KG;5KG 10KG; 100KG
- Release date
- 2019-09-02