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Amezinium methylsulfate

Product Name
Amezinium methylsulfate
CAS No.
30578-37-1
Chemical Name
Amezinium methylsulfate
Synonyms
lu1631;Risumic;regulton;Tenfortan;Amezinium;Supratonin;REGULTON (KNOLL);Amezinium mesylate;RISUMIC (DAINIPPON);ameziniometilsulfato
CBNumber
CB0166074
Molecular Formula
C12H15N3O5S
Formula Weight
313.33
MOL File
30578-37-1.mol
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Amezinium methylsulfate Property

Melting point:
176° (dec)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO : ≥ 34 mg/mL (108.51 mM)
form 
powder to crystal
color 
White to Light yellow
Merck 
14,394
CAS DataBase Reference
30578-37-1
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Safety

RTECS 
UR6066500
HS Code 
2933.59.8000
Toxicity
LD50 in mice, rats (mg/kg): 1630, 1410 orally; 40.4, 45.5 i.v. (Teschendorf)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2425
Product name
Amezinium Methyl Sulfate
Purity
>98.0%(HPLC)
Packaging
1g
Price
$40
Updated
2024/03/01
TCI Chemical
Product number
A2425
Product name
Amezinium Methyl Sulfate
Purity
>98.0%(HPLC)
Packaging
5g
Price
$195
Updated
2024/03/01
Biosynth Carbosynth
Product number
FA29468
Product name
Amezinium methyl sulfate
Packaging
250mg
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA29468
Product name
Amezinium methyl sulfate
Packaging
2g
Price
$200
Updated
2021/12/16
Chem-Impex
Product number
37582
Product name
Ameziniummethylsulfate,≥98%(HPLC)
Purity
≥98%(HPLC)
Packaging
5G
Price
$354.1
Updated
2021/12/16
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Amezinium methylsulfate Chemical Properties,Usage,Production

Originator

Regulton,Nordmark,W. Germany,1981

Definition

ChEBI: Amezinium metilsulfate is an azaheterocycle sulfate salt of amezinium. It is a sympathomimetic drug which suppresses noradrenaline reuptake and thereby elevating blood pressure. It is used for the treatment of low blood pressure in patients undergoing dialysis. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor, an antihypotensive agent, a sympathomimetic agent and an adrenergic uptake inhibitor. It contains an amezinium.

Manufacturing Process

18.7 parts of 1-phenyl-4-aminopyridazone-(6) and 19 parts of dimethyl sulfate in 400 parts of xylene are kept at 120°C for one hour while mixing well. The reaction mixture is suction filtered, 28 parts (89.5% of the theory) of 1-phenyl-4-amino-6-methoxypyridazinium methosulfate is obtained having a melting point of 173°C to 174°C after recrystallization from acetonitrile. The perchlorate has a melting point of 179°C to 182°C.

Therapeutic Function

Antihypotensive

Amezinium methylsulfate Preparation Products And Raw materials

Raw materials

Preparation Products

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Amezinium methylsulfate Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
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View Lastest Price from Amezinium methylsulfate manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Amezinium Methyl Sulfate 30578-37-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
Amezinium methylsulfate 30578-37-1
Price
US $1.00-2.00/KG
Min. Order
1KG
Purity
95.0-99.8%
Supply Ability
1KG;5KG 10KG; 100KG
Release date
2019-09-02

30578-37-1, Amezinium methylsulfateRelated Search:


  • 6-methoxy-1-phenylpyridazin-1-ium-4-amine methylsulfate
  • SUPRATONIN (GRUNENTHAL)
  • RISUMIC (DAINIPPON)
  • REGULTON (KNOLL)
  • AMEZINIUM METHYL SULFATE
  • 4-amino-6-methoxy-1-phenyl-pyridaziniumethylsulfate
  • Supratonin
  • Tenfortan
  • 4-Amino-6-methoxy-1-phenylpyridazin-1-ium
  • 4-amino-6-methoxy-1-phenylpyridazinium-methylsulfat
  • 4-amino-6-methoxy-1-phenylpyridaziniummethylsulfate
  • ameziniometilsulfato
  • ameziniummetilsulfat
  • ameziniummetilsulfate
  • lu1631
  • regulton
  • Amezinium mesylate
  • Amezinium
  • 1-Phenyl-4-amino-6-methoxypyridazinium methyl sulfate
  • Pyridazinium, 4-amino-6-methoxy-1-phenyl-, methyl sulfate (1:1)
  • Risumic
  • Amezinium Methyl Sulfate &gt
  • Pyridazinium, 4-amino-6-methoxy-1-phenyl-, methyl sulfate
  • 4-Amino-6-methoxy-1-phenylpyridazin-1-ium methyl sulfate
  • Amezinium methylsulfate,Lu 1631,Adrenergic Receptor,inhibit,Lu1631,Beta Receptor,Inhibitor,Amezinium
  • 30578-37-1
  • C12H15N3O5S
  • C11H12N3OCH3O4S