Description
ChemicalBook > CAS DataBase List > Anethole trithione

Anethole trithione

Description
Product Name
Anethole trithione
CAS No.
532-11-6
Chemical Name
Anethole trithione
Synonyms
Sulfarlem;AnetholTrithione;Trithio;Heporal;Mucinol;skf1717;Sulfogal;Felviten;SKF 1717;Sufralem
CBNumber
CB0168937
Molecular Formula
C10H8OS3
Formula Weight
240.36
MOL File
532-11-6.mol
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Anethole trithione Property

Melting point:
111°
Boiling point:
353.09°C (rough estimate)
Density 
1.4406 (rough estimate)
refractive index 
1.5080 (estimate)
storage temp. 
2-8°C
solubility 
soluble in Chloroform
form 
powder to crystal
color 
Orange-colored prisms from butyl acetate
Odor
very bitter taste
InChI
InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3
InChIKey
KYLIZBIRMBGUOP-UHFFFAOYSA-N
SMILES
S1C(C2=CC=C(OC)C=C2)=CC(=S)S1
CAS DataBase Reference
532-11-6(CAS DataBase Reference)
NIST Chemistry Reference
3H-1,2-Dithiole-3-thione, 5-(4-methoxyphenyl)-(532-11-6)
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Safety

HS Code 
2934.99.3000
Toxicity
LD50 orl-mus: 3850 mg/kg NIIRDN 6,25,82
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A3364
Product name
Anethole Trithione
Packaging
5G
Price
$70
Updated
2024/03/01
TCI Chemical
Product number
A3364
Product name
Anethole Trithione
Packaging
25G
Price
$278
Updated
2024/03/01
Biosynth Carbosynth
Product number
FA41106
Product name
Anethole trithione
Packaging
500mg
Price
$90
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA41106
Product name
Anethole trithione
Packaging
5G
Price
$375
Updated
2021/12/16
Matrix Scientific
Product number
074707
Product name
Anethole trithione
Purity
95+%
Packaging
5g
Price
$599
Updated
2021/12/16
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Anethole trithione Chemical Properties,Usage,Production

Description

Anise trisulfide, also known as bile vita, is a secretory choleretic drug, which can significantly enhance liver glutathione levels, significantly enhance glutamyl cysteine synthase, glutathione reductase and glutathione sulfur Transferase activity, reduce glutathione peroxidase activity, enhance liver cell viability, and increase bile secretion. Without increasing the burden on the liver, it can reduce liver portal pressure, eliminate liver congestion and other symptoms of hepatitis lesions, promote liver cell activation, and contribute to the improvement and recovery of liver function.

Originator

Sialor,Paladin Labs

Uses

Anethole trithione is a choleretic drug that can be effective in the treatment of dry mouth, including drug-induced xerostomia. Research suggests that Anethole trithione may exert its therapeutic effects by acting on the alpha-CGRP nerves in the salivary glands, which in turn promotes salivary secretion[1-2].

Definition

ChEBI: Anetholtrithion is a member of methoxybenzenes.

Manufacturing Process

1 mol anethol (1-methoxy-4-propenyl-benzene) and 3 mol sulfur were heated in an open vessel to temperature 190°-200°C. H2S was removed at this temperature. On cooling the reaction mixture was getting solid. The solid product was recrystallizated from acetone or ethanol to give the orange-red needles of 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione; MP 108.5°C.

Therapeutic Function

Salivation stimulant, Choleretic, Neuroprotective

Safety Profile

Poison by intramuscular route.Moderately toxic by ingestion and intraperitoneal routes.Experimental reproductive effects. When heated todecomposition it emits toxic fumes of SOx.

References

[1] TOSHIAKI NAGANO; Masaharu T. Enhancement of salivary secretion and neuropeptide (substance P, α-calcitonin gene-related peptide) levels in saliva by chronic anethole trithione treatment[J]. Journal of Pharmacy and Pharmacology, 2010. DOI:10.1211/0022357011778098.
[2] GLENERT U. Effects of chronic anethole trithione and amitriptyline treatment on rat parotid gland signalling[J]. European Journal of Pharmacology: Molecular Pharmacology, 1992. DOI:10.1016/0922-4106(92)90081-6.

Anethole trithione Preparation Products And Raw materials

Raw materials

Preparation Products

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Anethole trithione Suppliers

Huanggang Saikang Pharmaceutical Co.,Ltd
Tel
0713-8667500 13593655865
Fax
+86-713-8672800
Email
hgsaikang@163.com
Country
China
ProdList
9
Advantage
58
Changzhou Siyao Pharmaceuticals Co., Ltd
Tel
0519-88813110
Fax
0519-88825678
Email
siyao@czsiyao-pharm.com
Country
China
ProdList
26
Advantage
60
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9514
Advantage
66
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19179
Advantage
64
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View Lastest Price from Anethole trithione manufacturers

Sinoway Industrial co., ltd.
Product
Anethol Trithione 532-11-6
Price
US $0.00/Kg/Bag
Min. Order
2Kg/Bag
Purity
0.99
Supply Ability
20 tons
Release date
2022-12-02
Hebei Weibang Biotechnology Co., Ltd
Product
Anethole trithione 532-11-6
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-29
HUBEI VITORCOME PHARMACEUTICAL CO.,LTD
Product
Anethol Trithione 532-11-6
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
20 ton
Release date
2024-09-04

532-11-6, Anethole trithioneRelated Search:


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  • 5-(p-Methoxyphenyl)-1,2-dithiocyclopenten-3-thione
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