Anethole trithione
Description- Product Name
- Anethole trithione
- CAS No.
- 532-11-6
- Chemical Name
- Anethole trithione
- Synonyms
- Sulfarlem;AnetholTrithione;Trithio;Heporal;Mucinol;skf1717;Sulfogal;Felviten;SKF 1717;Sufralem
- CBNumber
- CB0168937
- Molecular Formula
- C10H8OS3
- Formula Weight
- 240.36
- MOL File
- 532-11-6.mol
Anethole trithione Property
- Melting point:
- 111°
- Boiling point:
- 353.09°C (rough estimate)
- Density
- 1.4406 (rough estimate)
- refractive index
- 1.5080 (estimate)
- storage temp.
- 2-8°C
- solubility
- soluble in Chloroform
- form
- powder to crystal
- color
- Orange-colored prisms from butyl acetate
- Odor
- very bitter taste
- InChI
- InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3
- InChIKey
- KYLIZBIRMBGUOP-UHFFFAOYSA-N
- SMILES
- S1C(C2=CC=C(OC)C=C2)=CC(=S)S1
- CAS DataBase Reference
- 532-11-6(CAS DataBase Reference)
- NIST Chemistry Reference
- 3H-1,2-Dithiole-3-thione, 5-(4-methoxyphenyl)-(532-11-6)
Safety
- HS Code
- 2934.99.3000
- Toxicity
- LD50 orl-mus: 3850 mg/kg NIIRDN 6,25,82
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A3364
- Product name
- Anethole Trithione
- Packaging
- 5G
- Price
- $70
- Updated
- 2024/03/01
- Product number
- A3364
- Product name
- Anethole Trithione
- Packaging
- 25G
- Price
- $278
- Updated
- 2024/03/01
- Product number
- C6709
- Product name
- Anethole Trithione
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 37633
- Product name
- Anetholetrithione,≥98%(GC)
- Purity
- ≥98%(GC)
- Packaging
- 5G
- Price
- $61.73
- Updated
- 2021/12/16
- Product number
- CS-4781
- Product name
- Anethole Trithione
- Purity
- 99.67%
- Packaging
- 100mg
- Price
- $72
- Updated
- 2021/12/16
Anethole trithione Chemical Properties,Usage,Production
Description
Anise trisulfide, also known as bile vita, is a secretory choleretic drug, which can significantly enhance liver glutathione levels, significantly enhance glutamyl cysteine synthase, glutathione reductase and glutathione sulfur Transferase activity, reduce glutathione peroxidase activity, enhance liver cell viability, and increase bile secretion. Without increasing the burden on the liver, it can reduce liver portal pressure, eliminate liver congestion and other symptoms of hepatitis lesions, promote liver cell activation, and contribute to the improvement and recovery of liver function.
Originator
Sialor,Paladin Labs
Uses
Anethole trithione is a choleretic drug that can be effective in the treatment of dry mouth, including drug-induced xerostomia. Research suggests that Anethole trithione may exert its therapeutic effects by acting on the alpha-CGRP nerves in the salivary glands, which in turn promotes salivary secretion[1-2].
Definition
ChEBI: Anetholtrithion is a member of methoxybenzenes.
Manufacturing Process
1 mol anethol (1-methoxy-4-propenyl-benzene) and 3 mol sulfur were heated in an open vessel to temperature 190°-200°C. H2S was removed at this temperature. On cooling the reaction mixture was getting solid. The solid product was recrystallizated from acetone or ethanol to give the orange-red needles of 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione; MP 108.5°C.
Therapeutic Function
Salivation stimulant, Choleretic, Neuroprotective
Safety Profile
Poison by intramuscular route.Moderately toxic by ingestion and intraperitoneal routes.Experimental reproductive effects. When heated todecomposition it emits toxic fumes of SOx.
References
[1] TOSHIAKI NAGANO; Masaharu T. Enhancement of salivary secretion and neuropeptide (substance P, α-calcitonin gene-related peptide) levels in saliva by chronic anethole trithione treatment[J]. Journal of Pharmacy and Pharmacology, 2010. DOI:10.1211/0022357011778098.
[2] GLENERT U. Effects of chronic anethole trithione and amitriptyline treatment on rat parotid gland signalling[J]. European Journal of Pharmacology: Molecular Pharmacology, 1992. DOI:10.1016/0922-4106(92)90081-6.
Anethole trithione Preparation Products And Raw materials
Raw materials
Preparation Products
Anethole trithione Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from Anethole trithione manufacturers
- Product
- Anethol Trithione 532-11-6
- Price
- US $0.00/Kg/Bag
- Min. Order
- 2Kg/Bag
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2022-12-02
- Product
- Anethole trithione 532-11-6
- Price
- US $10.00/KG
- Min. Order
- 100KG
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-11-29
- Product
- Anethol Trithione 532-11-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 20 ton
- Release date
- 2024-09-04