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L-QUEBRACHITOL

Product Name
L-QUEBRACHITOL
CAS No.
642-38-6
Chemical Name
L-QUEBRACHITOL
Synonyms
QUEBRACHITOL;L-QUEBRACHITOL;(-)-Quebrachitol;(-)-Quebrachitol,99%;2-o-methyl-l-inositol;QINGYANGSHENGENIN (RG);3-O-METHYL-L-CHIRO-INOSITOL;2-O-METHYL-L-CHIRO-INOSITOL;1L-2-O-METHYL-CHIRO-INOSITOL;L-chiro-Inositol, 2-O-methyl-
CBNumber
CB0169479
Molecular Formula
C7H14O6
Formula Weight
194.18
MOL File
642-38-6.mol
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L-QUEBRACHITOL Property

Melting point:
190-198 °C
Boiling point:
250.62°C (rough estimate)
Density 
1.56±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 
1.572
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO (Slightly), Water (Sparingly)
form 
Solid
pka
12.98±0.70(Predicted)
color 
White to Off-White
LogP
-0.740 (est)
CAS DataBase Reference
642-38-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
Q990090
Product name
L-Quebrachitol
Packaging
500mg
Price
$100
Updated
2021/12/16
TRC
Product number
Q990090
Product name
L-Quebrachitol
Packaging
100mg
Price
$45
Updated
2021/12/16
Usbiological
Product number
300543
Product name
L-Quebrachitol|
Packaging
20mg
Price
$382
Updated
2021/12/16
Biosynth Carbosynth
Product number
FQ02486
Product name
L-Quebrachitol
Packaging
1g
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FQ02486
Product name
L-Quebrachitol
Packaging
10g
Price
$550
Updated
2021/12/16
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L-QUEBRACHITOL Chemical Properties,Usage,Production

Chemical Properties

white to off-white powder

Uses

L-Quebrachitol is a methoxy analog of inositol that can be isolated from plants. L-Quebrachitol has free-radical scavenging, gastroprotection, anti-platelet aggregation and anti-diabetic activity. L-Quebrachitol promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway[1][2][3].

Definition

ChEBI: L-Quebrachitol is a member of cyclohexanols.

in vivo

L-Quebrachitol (125 mg/kg) significantly reduces weight gain, increases bone mineral density and bone calcium content of ovariectomized rats[2].

References

[1] Yodthong T, et al. l-Quebrachitol Promotes the Proliferation, Differentiation, and Mineralization of MC3T3-E1 Cells: Involvement of the BMP-2/Runx2/MAPK/Wnt/β-Catenin Signaling Pathway. Molecules. 2018 Nov 26;23(12). DOI:10.3390/molecules23123086
[2] Li Y, et al. L-quebrachitol extracted from industrial rubber serum: a study on its antioxidant activities and bone mineral density enhancing functions[J]. Industrial Crops and Products, 2023, 201: 116943.
[3] Mu Y, et al. Sea buckthorn leaf l-quebrachitol extract for improved glucose and lipid metabolism in insulin resistant HepG2 Cells[J]. Bioresources, 2022, 17(1): 527.

L-QUEBRACHITOL Preparation Products And Raw materials

Raw materials

Preparation Products

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L-QUEBRACHITOL Suppliers

Belgium 1 Canada 1 China 123 Europe 1 France 1 Germany 2 India 2 Italy 1 Japan 2 New Zealand 1 South Korea 1 Switzerland 4 The Netherlands 1 Ukraine 1 United Kingdom 11 United States 21 USA 1 Global 175
Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
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View Lastest Price from L-QUEBRACHITOL manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
L-QUEBRACHITOL 642-38-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
L-QUEBRACHITOL 642-38-6
Price
US $120.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2018-07-26

642-38-6, L-QUEBRACHITOLRelated Search:

GLUCOTROPAEOLIN Xanthiazone Z-LIGUSTILIDE Camphene Hydroxycitric acid Isorhamnetin menisdaurin 4-Methoxybenzoic acid 2-(4-hydroxyphenyl)ethyl ester ALPHA-CARYOPHYLLENE Xylitol L-(-)-CHIRO-INOSITOL L-QUEBRACHITOL HEXA(2-CYANOETHOXY) CYCLOHEXANE 1,2:3,4-DI-O-CYCLOHEXYLIDENE-5-O-METHYL-L-CHIRO-INOSITOL L-CHIRO-INOSITOL DIACETONIDE INOSITOL HEXAACETATE QUEBRACHITOL DIACETONIDE 1,2:5,6-BIS-O-(1-METHYLETHYLIDENE)-1L-CHIRO-INOSITOL

  • L-CHIRO-INOSITOL 2-METHYL ETHER
  • L-QUEBRACHITOL
  • QUEBRACHITOL
  • 1L-2-O-METHYL-CHIRO-INOSITOL
  • 2-O-METHYL-L-CHIRO-INOSITOL
  • 2-O-METHYL-1,2,4/3,5,6-HEXAHYDROXYCYCLOHEXANE
  • 3-O-METHYL-L-CHIRO-INOSITOL
  • (1R,2S,3S,4S,5R,6R)-6-Methoxycyclohexane-1,2,3,4,5-pentaol
  • L-chiro-Inositol, 2-O-methyl-
  • 2-o-methyl-l-inositol
  • 2-O-Methyl-1,2,4/3,5,6-hexahydroxycyclohexane, 2-O-Methyl-L-inositol, L-chiro-Inositol 2-methyl ether, L-Quebrachitol
  • 2-O-Methyl-1,2,4,3,5,6-hexahydroxycyclohexane, L-chiro-Inositol 2-methyl ether
  • (-)-Quebrachitol,99%
  • (-)-Quebrachitol2-O-Methyl-L-inositol
  • QINGYANGSHENGENIN (RG)
  • L-Quebrachitol, 98%, from Hippophae rhamnoides L.
  • (-)-Quebrachitol
  • L-quebrachitol, 10 mM in DMSO
  • 642-38-6
  • Miscellaneous Natural Products