GALANTIDE

Product Name: GALANTIDE
CAS No.: 138579-66-5
Chemical Name: GALANTIDE
Synonyms: M15;GALANTIDE;M 15 (peptide);Galantide, M15;GalantideGalanti;GALANTIDE| Galantide;Galantide, ≥90% (HPLC);GWTLNSAGYLLGPQQFFGLM-NH2;Galanin(1-13)-substance P(5-11);Rabbit Anti-PKA R2/PKA IIÎ
CBNumber: CB0173935
Molecular Formula: C104H151N25O26S
Formula Weight: 2199.53
MOL File: 138579-66-5.mol

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GALANTIDE Property

Boiling point:: 2345.4±65.0 °C(Predicted)
Density: 1.305±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: Soluble in DMSO
form: Solid
pka: 9.82±0.15(Predicted)
color: White to off-white
Sequence: Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G1278
Product name: Galantide
Purity: ≥90% (HPLC)
Packaging: 0.5mg
Price: $707
Updated: 2023/06/20

ChemScene

Product number: CS-7011
Product name: Galantide
Purity: 99.27%
Packaging: 500ug
Price: $168
Updated: 2021/12/16

ChemScene

Product number: CS-7011
Product name: Galantide
Purity: 99.27%
Packaging: 1mg
Price: $288
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0001405
Product name: GALANTIDE
Purity: 95.00%
Packaging: 0.5MG
Price: $632.94
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0001405
Product name: GALANTIDE
Purity: 95.00%
Packaging: 1MG
Price: $753.12
Updated: 2021/12/16

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GALANTIDE Chemical Properties,Usage,Production

Uses

Galantide, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in the rat hypothalamus. Galantide dose dependently (IC50=1.0 nM) antagonizes the galanin-mediated inhibition of the glucose-induced insulin secretion from mouse pancreatic islets. Galantide appears to bind to a single population of SP receptors (KD~40 nM)[1][2][3].

in vivo

Intracerebroventricular injection of galanin (5 micrograms/rat) inhibited sexual behavior in experienced male rats--without producing any other locomotor or behavioral deficit-, injection of the galanin antagonist, galantide, by the same route (1 or 2 micrograms/rat) stimulated sexual behavior (improving arousal, motivation and performance indexes) and antagonized the effect of galanin^[2]. Galantide ameliorates mild acute pancreatitis (AP). Galantide significantly reduces AP-induced hyperenzymemia by 41–49%^[3]. Galantide has been found to improve social memory in 'socialrecognition' test when i.c.v. administered at doses varying from 6-6000 nM^[4].

References

[1] Langel U, et al. Design of chimeric peptide ligands to galanin receptors and substance P receptors. Int J Pept Protein Res. 1992;39(6):516-522. DOI:10.1111/j.1399-3011.1992.tb00282.x
[2] Lindskog S, et al. The novel high-affinity antagonist, galantide, blocks the galanin-mediated inhibition of glucose-induced insulin secretion. Eur J Pharmacol. 1992;210(2):183-188. DOI:10.1016/0014-2999(92)90669-u
[3] Mulvaney JM, et al. Galantide distinguishes putative subtypes of galanin receptors in mudpuppy parasympathetic neurons. Eur J Pharmacol. 1995;287(1):97-100. DOI:10.1016/0014-2999(95)00623-6

GALANTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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GALANTIDE Suppliers

China 91 France 1 Germany 3 Switzerland 1 United States 12 USA 1 Global 109

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
Fax: 0551-65326641
Email: info@cellmano.com
Country: China
ProdList: 1010
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Watson Biotechnology Co.,Ltd

Tel: 027-59207879 1972026995 18140587686
Fax: QQ：1972026995
Email: sales@3600chem.com
Country: China
ProdList: 4446
Advantage: 55

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9941
Advantage: 58

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View Lastest Price from GALANTIDE manufacturers

Career Henan Chemical Co

Product: GALANTIDE 138579-66-5
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-13

138579-66-5, GALANTIDERelated Search:

Propylene oxide RABBIT COMPLEMENT (HLA-DR) GLY-LEU-MET-NH2 GALANIN (2-11) PORCINE, RAT GALANTIDE SUBSTANCE P (4-11) SUBSTANCE P (5-11)

Galanin(1-13)-substance P(5-11)

Gly-L-Trp-L-Thr-L-Leu-L-Asn-L-Ser-L-Ala-Gly-L-Tyr-L-Leu-L-Leu-Gly-L-Pro-L-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2

L-Methioninamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-

Galanin (1-13)-Substance P (5-11), amide, Galantide

GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET AMIDE

GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2

GALANTIDE

GALANIN (1-13)-SUBSTANCE P (5-11) AMIDE

GWTLNSAGYLLGPQQFFGLM-NH2

H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2

M15

gly-trp-thr-leu-asn-ser-ala-gly-tyr-*leu-leu-gly-

GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-*LEU -LEU-GLY-PR

M 15 (peptide)

Galanin (1-13)-Substance P (5-11) aMide Galantide, M15

Galantide, M15

GalantideGalanti

GALANTIDE| Galantide

Galantide, ≥90% (HPLC)

Rabbit Anti-PKA R2/PKA II&Icirc

138579-66-5

C104H151N25O26S1

C104H151N25O26S

Biochemicals and Reagents

Amino Acids and Peptides

BioChemical

Galanins

Gastrointestinal Products

Peptides

Galanin receptor

Peptide