ChemicalBook > CAS DataBase List > CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE

CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE

Product Name
CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE
CAS No.
130465-39-3
Chemical Name
CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE
Synonyms
A 68930;A68930HCl;A 68930 hydrochlorid;A 68930 HYDROCHLORIDE;A-68930 hydrochloride (A68930);cis-1-(AMinoMethyl)-3-phenylisochroMan-5,6-diol hydrochloride;(1R,3S)-1-(AMinoMethyl)-3-phenylisochroMan-5,6-diol hydrochloride;(1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran;1-(aminomethyl)-3,4-dihydro-3-phenyl-1H-2-Benzopyran-5,6-diol hydrochloride;cis-(±)-1-Aminoethyl-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride
CBNumber
CB0174886
Molecular Formula
C16H18ClNO3
Formula Weight
307.77
MOL File
130465-39-3.mol
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CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE Property

storage temp. 
−20°C
solubility 
H2O: ~9 mg/mL, soluble
form 
solid
color 
off-white
Water Solubility 
Soluble to 50 mM in water
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris
Product number
1534
Product name
A-68930 hydrochloride
Purity
≥98%(HPLC)
Packaging
50
Price
$682
Updated
2021/12/16
Tocris
Product number
1534
Product name
A-68930 hydrochloride
Purity
≥98%(HPLC)
Packaging
10
Price
$162
Updated
2021/12/16
Usbiological
Product number
254474
Product name
A 68930 hydrochloride
Packaging
10mg
Price
$446
Updated
2021/12/16
TRC
Product number
A965318
Product name
A-68930 hydrochloride
Packaging
1mg
Price
$105
Updated
2021/12/16
ApexBio Technology
Product number
B6779
Product name
A-68930 hydrochloride
Packaging
50mg
Price
$990
Updated
2021/12/16
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CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

A 68930 Hydrochloride is a potent and selective agonist at the D1-like dopamine receptor. It demontrated neuroprotective and anti-stress effects in rat model (1,2).

Biological Activity

Potent and selective D 1 -like dopamine receptor agonist (EC 50 values are 2.1 and 3910 nM for D 1 -like and D 2 -like receptors respectively). Centrally active following systemic administration in vivo .

storage

Desiccate at +4°C

References

[1]. kebabian jw, briggs c, britton dr, et al. a68930: a potent and specific agonist for the d-1 dopamine receptor. am j hypertens, 1990, 3(6 pt 2): 40s-42s.
[2]. salmi p. independent roles of dopamine d1 and d2/3 receptors in rat thermoregulation. brain res, 1998, 781(1-2): 188-193.
[3]. deveney am, waddington jl. psychopharmacological distinction between novel full-efficacy "d1-like" dopamine receptor agonists. pharmacol biochem behav, 1997, 58(2): 551-558.
[4]. rasheed n, ahmad a, al-sheeha m, et al. neuroprotective and anti-stress effect of a68930 in acute and chronic unpredictable stress model in rats. neurosci lett, 2011, 504(2): 151-155.

CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE Suppliers

China 19 Germany 2 Switzerland 1 United Kingdom 1 United States 7 USA 1 Global 31
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130465-39-3, CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDERelated Search:

2-AMINO-1-(2-IODO-PHENYL)-ETHANOL HYDROCHLORIDE C-ISOCHROMAN-1-YL-METHYLAMINE CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE L-NORADRENALINE HYDROCHLORIDE A-METHYLBENZYL ETHER

  • A 68930 HYDROCHLORIDE
  • CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE
  • A 68930
  • A68930HCl
  • cis-(±)-1-Aminoethyl-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride
  • cis-1-(AMinoMethyl)-3-phenylisochroMan-5,6-diol hydrochloride
  • (1R,3S)-1-(AMinoMethyl)-3-phenylisochroMan-5,6-diol hydrochloride
  • 1-(aminomethyl)-3,4-dihydro-3-phenyl-1H-2-Benzopyran-5,6-diol hydrochloride
  • A-68930 hydrochloride (A68930)
  • (1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran
  • A 68930 hydrochlorid
  • 130465-39-3
  • C16H17NO3HCl
  • Dopamine receptor