4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID

Product Name: 4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID
CAS No.: 141179-72-8
Chemical Name: 4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID
Synonyms: TIMTEC-BB SBB006651;RARECHEM AL BO 0635;à,à,à,4-tetrafluoro-o-toluic acid;α,α.α,4-Tetrafluoro-o-toluic Acid;2-trifluoromethyl-4-fluoro-benzoic acid;4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID;Benzoicacid, 4-fluoro-2-(trifluoromethyl)-;4-Fluoro-2-(trifluoromethyl)benzoicacid98%;4-Fluoro-2-(trifluoromethyl)benzoicAcid>4-Fluoro-2-(trifluoromethyl)benzoic acid 98%
CBNumber: CB0177221
Molecular Formula: C8H4F4O2
Formula Weight: 208.11
MOL File: 141179-72-8.mol

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4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID Property

Melting point:: 121-124 °C (lit.)
Boiling point:: 239.0±40.0 °C(Predicted)
Density: 1.4412 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Methanol
pka: 3.17±0.36(Predicted)
form: Needle-Like Crystalline Powder
color: Slightly yellow
InChI: InChI=1S/C8H4F4O2/c9-4-1-2-5(7(13)14)6(3-4)8(10,11)12/h1-3H,(H,13,14)
InChIKey: JUHPDXOIGLHXTC-UHFFFAOYSA-N
SMILES: C(O)(=O)C1=CC=C(F)C=C1C(F)(F)F
CAS DataBase Reference: 141179-72-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29163990
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 436135
Product name: 4-Fluoro-2-(trifluoromethyl)benzoic acid
Purity: 98%
Packaging: 5g
Price: $39.1
Updated: 2022/05/15

TCI Chemical

Product number: F0577
Product name: 4-Fluoro-2-(trifluoromethyl)benzoic Acid
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $28
Updated: 2025/07/31

TCI Chemical

Product number: F0577
Product name: 4-Fluoro-2-(trifluoromethyl)benzoic Acid
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $96
Updated: 2025/07/31

TRC

Product number: F598713
Product name: 4-Fluoro-2-(trifluoromethyl)benzoic acid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: F598713
Product name: 4-Fluoro-2-(trifluoromethyl)benzoic acid
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID Chemical Properties,Usage,Production

Chemical Properties

slightly yellow needle-like crystalline powder

Uses

4-Fluoro-2-(trifluoromethyl)benzoic acid is a substituted benzoic acid derivative. Molecular orbital and empirical methods have been utilized to determine its computed steric and electronic properties.

General Description

4-Fluoro-2-(trifluoromethyl)benzoic acid is a substituted benzoic acid derivative. Molecular orbital and empirical methods have been utilized to determine its computed steric and electronic properties.

Synthesis

Magnesium powder and a small pellet of iodine were added to the reaction flask, which was dried at high temperature, and the reaction system was then nitrogen-protected (air in the reaction system was replaced with nitrogen) through a double-row tube. Anhydrous tetrahydrofuran and 2-bromo-5-fluorobenzotrifluoride were then added to the reaction system under nitrogen atmosphere and the resulting mixture system was heated to reflux in an oil bath and the reaction was stirred at reflux for 2 hours to prepare the corresponding format reagents. The reaction system was cooled to room temperature and then the nitrogen in the reaction system was replaced with the corresponding carbon dioxide and the resulting reaction mixture was stirred and reacted at room temperature overnight. After the reaction, hydrochloric acid was added to the reaction system to acidify the reaction system, the reaction mixture was extracted with ethyl acetate and water, the organic layer was separated and dried, the organic layer was concentrated and the residue was purified by silica gel column chromatography to obtain the target molecule 4-fluoro-2-(trifluoromethyl)benzoic acid.

4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID Suppliers

Americas 1 Belgium 2 CHINA 174 Europe 3 France 1 Germany 5 India 8 Italy 1 Japan 2 Switzerland 2 The Netherlands 1 United Kingdom 19 United States 35 Global 254

Shanghai Harvest Chemical Industrial Co., Ltd.

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View Lastest Price from 4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID manufacturers

Hebei Fengjia New Material Co., Ltd

Product: 4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID 141179-72-8
Price: US $3.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2024-08-16

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID 141179-72-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-11-13

Speranza Chemical Co., Ltd.

Product: 4-fluoro-2-(trifluoromethyl)benzoic acid 141179-72-8
Price: US $250.00/KG
Min. Order: 1KG
Purity: 98%+
Supply Ability: 300 Tons/ year
Release date: 2019-12-25

141179-72-8, 4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACIDRelated Search:

RARECHEM AL BO 0635

TIMTEC-BB SBB006651

à,à,à,4-tetrafluoro-o-toluic acid

4-Fluoro-2-(trifluoromethyl)benzoic acid 98%

4-Fluoro-2-(trifluoromethyl)benzoicacid98%

4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID

ALPHA,ALPHA,ALPHA,4-TETRAFLUORO-O-TOLUIC ACID

α,α.α,4-Tetrafluoro-o-toluic Acid

4-Fluoro-2-(trifluoroMethyl)benzoic acid, 97+%

Benzoicacid, 4-fluoro-2-(trifluoromethyl)-

2-Carboxy-5-fluorobenzotrifluoride, alpha,alpha,alpha,4-Tetrafluoro-o-toluic acid

2-trifluoromethyl-4-fluoro-benzoic acid

4-Fluoro-2-(trifluoromethyl)benzoicAcid&gt

141179-72-8

141179-7208

C8

Carboxylic Acids

Carbonyl Compounds

Building Blocks

Organic Building Blocks

ARYL ACID

Fluorine series

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

Benzoic acid

C8

Carbonyl Compounds

Carboxylic Acids

Fluorobenzene